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Poster Area

Oral Poster Antiretroviral Therapy

Chairs: R. Maserati, P. Nasta

OP 1Evaluation of total HIV-DNA and residual viremia in HIV-1 infected patients who continue a two-drug regimen with dolutegravir plus one reverse transcriptase inhibitor or switch to elvitegravir/cobicistat/emtricitabine/tenofovir alafenamide enrolled in the Be-OnE Study

M.M. Santoro1, N. Gianotti2, L. Galli2, R. Scutari1, C. Alteri3, A. Poli2, L. Piermatteo1, A. Bigoloni2, C.F. Perno3, A. Lazzarin2, F. Ceccherini-Silberstein1, A. Castagna2,4

1University of Rome “Tor Vergata”, Rome, 2Infectious Diseases, IRCCS San Raffaele, Milan, 3University of Milan, Milan, 4Vita-Salute San Raffaele University, Milan

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OP 2Durability and liver safety of InSTI-based regimens in HIV-infected patients with advanced liver fibrosis or cirrhosis: data from the ODOACRE cohort

A. Lanari1, B. Rossetti2, A. Ciccullo3,4, V. Borghi5, A. Dusina3,4, C. Cassol1, G. Cuomo5, A. D’Angelillo3,4, F. Montagnani1, C. Mussini5, S. Di Giambenedetto3,4, M. Fabbiani2

1UOC Malattie Infettive e Tropicali, Dipartimento di Biotecnologie Mediche, Università di Siena, Siena, 2UOC Malattie Infettive e Tropicali, Azienda Ospedaliero-Universitaria Senese, Siena, 3Università Cattolica del Sacro Cuore, Dipartimento di Sicurezza e Bioetica Sezione Malattie Infettive, Rome, 4UOC Malattie Infettive, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, 5Clinica Malattie Infettive e Tropicali, Azienda Ospedaliero Universitaria di Modena, Modena

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OP 3Prevalence of transmitted resistance mutations to rilpivirine and doravirine in treatment-naive patients in a large clinical and resistance database

F. Lombardi1, V. Costabile2, A. Lai3, L. Taramasso4, M. Siano3, B. Bruzzone5, V. Micheli6, A. Callegaro7, E. Paolini8, F. Maggiolo9, G. Colao10, P. Meraviglia6, P. Bagnarelli11, A. Shallvari12, S. Rusconi3

1Università Cattolica del Sacro Cuore, Dipartimento di Sicurezza e Bioetica Sezione Malattie Infettive, Roma, Italy, 2Department of Pathophysiology and Transplantation, University of Milan, Milan, Italy, 3Infectious Disease Unit, DIBIC Luigi Sacco, University of Milan, Milan, Italy, 4Infectious Diseases Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy, 5Hygiene Unit, IRCCSAOU San Martino-IST, Genoa, Italy, 6Laboratorio Microbiologia Ospedale L. Sacco ,Seconda Divisione Malattie Infettive, Milan, Italy, 7Department of Laboratory Medicine, ASST Papa Giovanni XXIII, Bergamo, Italy, 8Servizio Immunoematologia e Medcina Trasfusionale, Cremona Hospital, Cremona, Italy, 9Division of Infectious Diseases, ASST Papa Giovanni XXIII, Bergamo, Italy, 10Laboratory of Virology, Careggi Hospital, Firenze, Italy, 11Virology Unit, Azienda Ospedaliera Universitaria Ospedali Riuniti di Ancona, Ancona, Italy, 12IPRO - InformaPRO S.r.l., Rome

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OP 4Efficacy and tolerability of bictegravir/ tenofovir alafenamide/ emtricitabine as a switch strategy in a cohort of antiretroviral therapy treatment-experienced HIV-1-infected patients

F. Lagi1, A. Botta1, M. Trotta2, B. Borchi2, P. Rogasi2, P. Nizzoli3, A. Bartoloni1,2, G. Sterrantino1

1Department of Experimental and Clinical Medicine, University of Florence, Florence Italy, 2Infectious and Tropical Diseases Unit, Careggi University and Hospital, Florence, Italy, 3Department of Pharmaceuticals, USL Toscana Centro, Careggi- Pharmacy, Florence, Italy

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OP 5Viral rebound in pts with suppressed HIV-RNA on a 2 or 3-drug regimen: a comparison

A. Borghetti1, A. Giacomelli2,3, M. Colafigli4, A. Lanari5, L. Celani6, V. Borghi7, A. Ciccullo8, S. Rusconi2,3, A. Latini4, F. Lombardi8, L. Oreni2,3, C. Mussini7, S. Di Giambenedetto1,8

1Fondazione Policlinico Universitario A. Gemelli IRCCS, Roma Italia, UOC malattie infettive, 2III Infectious Disease Unit, ASST-FBF-Sacco, Milan, Italy, 3Department of Biomedical and Clinical Sciences DIBIC L. Sacco, University of Milan, Milan, Italy, 4Infectious Dermatology and Allergology, IFO San Gallicano, Rome, Italy, 5Hospital Department of Specialized and Internal Medicine, Infectious Diseases Unit, University Hospital of Siena, Siena, Italy, 6Department of Public Health and Infectious Diseases, Sapienza University of Rome, Rome, Italy, 7Clinica delle Malattie Infettive e Tropicali dell'Università di Modena e Reggio Emilia, Modena, Italy, 8Università Cattolica del Sacro Cuore, Roma Italia, Istituto di Clinica Malattie Infettive

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OP 6Optically traceable PLGA Nanoparticles improve the ability of darunavir to cross the blood brain barrier and inhibit MMP-9. Implications for the Treatment of HIV-Associated Neurological Disorders

S. Milella1, N. Depalo2, A. Panniello2, F. Rizzi2, V. Laquintana3, N. Denora3, C.M. Mastroianni4, G.M. Liuzzi1, M.L. Curri5, T. Latronico1

1Dipartimento di Bioscienze, Biotecnologie e Biofarmaceutica, Università degli Studi di Bari Aldo Moro, Italy, 2Consiglio Nazionale delle Ricerche, Istituto per i Processi Chimico-Fisici, Bari, Italy, 3Dipartimento di Farmacia-Scienze del Farmaco, Università degli Studi di Bari Aldo Moro, Bari, Italy, 4Dipartimento di Sanità Pubblica e Malattie Infettive della Facoltà di Farmacia e Medicina, Università degli Studi di Roma "La Sapienza", Roma, Italy, 5Dipartimento di Chimica, Università degli Studi di Bari Aldo Moro, Bari, Italy

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OP 7Effectiveness and long-term durability of rilpivirine-based single tablet regimens in a large cohort of HIV-infected patients. A preliminary analysis

L. Magnasco1, R. Pincino1, G. Sarteschi1, S. Lo Caputo2, S. Bruno2, S. Ferrara2, F. Briano1, D. Malucelli3, S. Beltramini4, E. Sasso4, A. Di Biagio1

1U.O. Clinica Malattie Infettive, University of Genoa (DISSAL) and Ospedale Policlinico San Martino-IRCCS per L'Oncologia, Genova, 2U.O. Clinica Malattie Infettive, University of Foggia, 3SANTALUCIA PHARMA APPS©, Località Gragnanino, Gragnano Trebbiense, 4U.O. Farmacia, Ospedale Policlinico San Martino-IRCCS per l'Oncologia, Genoa

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OP 8Increase in body weight after a year of INI-exposure in a multicenter italian cohort

A. Ciccullo1, G. Baldin1,2, G. Sterrantino3, M. Colafigli4, G. d’Ettorre5, A. Lanari6, G. Greco7, A. De Vito8, L. Celani5, A. Giacomelli9, F. Lagi3, S. Rusconi9, S. Di Giambenedetto1,10, G. Madeddu8

1Section of Infectious Diseases, Department of Safety and Bioethics, Catholic University of the Sacred Heart, Rome, Italy, 2Mater Olbia Hospital, Olbia, Italy, 3Infectious Diseases Unit, Department of Clinical and Experimental Medicine, University of Florence, Florence, Italy, 4Infectious Dermatology and Allergology Unit, S. Gallicano Institute IRCCS, Rome, Italy, 5Department of Public Health and Infectious Diseases, Azienda Policlinico Umberto I, Rome, Italy, 6Infectious Diseases Unit, Siena University Hospital, Siena, Italy, 7Department of Medical and Surgical Sciences, Unit of Infectious and Tropical Diseases, "Magna Graecia" University, Catanzaro, Italy, 8Department of Medical, Surgical and Experimental Sciences, University of Sassari, Sassari, Italy, 9Infectious Diseases Unit, DIBIC Luigi Sacco, University of Milan, Milan, Italy, 10Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Roma, Italia

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OP 9Treatment outcome among HIV-1 infected patients who started first-line ART pending GRT results from 2015 to 2018

D.F. Bavaro1, G. Pasculli2,3, A. De Vito4, R. Lattanzio1, F. Saladini5, L. Magnasco6, R. Yagai Bouba7, R. Pincino6, R. Corsini8, S. Arima9, F. Incardona3,10, B. Rossetti11, A. Bezenchek10, V. Borghi12, A. Di Biagio6

1Department of Biomedical Sciences and Human Oncology, Clinic of Infectious Diseases, University of Bari, Bari, Italy, 2Department of Computer, Control, and Management Engineering Antonio Ruberti (DIAG), La Sapienza University, Rome, Italy, 3EuResist Network, ROme, Italy, 4Unit of Infectious Diseases, Department of Medical, Surgical and Experimental Sciences, University of Sassari, Sassari, Italy, 5Department of Medical Biotechnologies, University of Siena, Italy, 6Department of Health’s Sciences, University of Genoa, Genoa, Italy, 7Department of experimental medicine, University of Rome “Tor Vergata”, Rome, Italy. 8Infectious Diseases Unit, Azienda USL-IRCCS di Reggio Emilia, 9Department of Methods and Model for Economy Territory and Finance, University of Rome “La Sapienza”, Rome, Italy, 10INFORMAPRO Srl, Rome, Italy, 11Infectious Diseases Unit, Azienda Ospedaliero-Universitaria Senese, Siena, Italy, 12Clinic of Infectious Disease, Azienda Ospedaliero Universitaria di Modena

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OP 10Retrospective analysis of reasons and characteristics of switches in a cohort of women affected by HIV infection referring to D. Cotugno Hospital, Naples, period 2017-2019

F.M. Fusco1, V. Rizzo2, M.A. Carleo2, S. Mascolo2, R. Viglietti1, M. D’Abbraccio2, V. Esposito2

1UOC Infezioni Sistemiche e dell’Immunodepresso, P.O. “D. Cotugno”, Azienda Ospedaliera dei Colli, Naples, Italy, 2UOC Immunodeficienze e Malattie Infettive di Genere, P.O. “D. Cotugno”, Azienda Ospedaliera dei Colli, Naples, Italy

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OP 11Assessing the feasibility of 2-drug regimens as switch strategies in a multicenter cohort

A. Borghetti1,2, A. Ciccullo2, M. Colafigli3, E. Anzalone4, A. Pennica5, A. Dusina2, D. Farinacci2, A. Latini3, F. Di Sora6, S. Di Giambenedetto1,2

1Fondazione Policlinico Universitario Agostino Gemelli IRCCS, UOC Malattie Infettive, Roma, Italy, 2Dipartimento di Sicurezza e Bioetica, Sezione di Malattie Infettive, Università Cattolica del Sacro Cuore, Roma, Italy, 3Dermatologia Infettivologica ed Allergologica, Istituto Dermatologico San Gallicano IRCCS, Roma, Italy, 4UOSD AIDS, Presidio Ospedaliero Frosinone, Italy, 5Facoltà di Medicina e Psicologia "La Sapienza", Presidio Ospedaliero S. Andrea, Roma, Italy, 6Dipartimento di Malattie Infettive, Ospedale S. Giovanni Addolorata, Roma, Italy

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OP 12Risk of failure in dual vs triple therapy in naïve HIV-patients: a meta-analysis

A. Russo, M. Pisaturo, L. Onorato, S. Martini, S. Simona, P. Maggi, N. Coppola

University of Campania Luigi Vanvitelli, Naples, Italy

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Oral Poster Basic Science and Immunology

Chairs: L. Butini, S. Piconi

OP 13DAA treatment fails to restore the inflammatory profile both in HCV/HIV and in HCV infected patients

V. Bordoni, A. Vergori, S. Notari, C. Gruber, C. Montaldo, M. Tripodi, E. Cimini, R. Casetti, G. Grassi, A. Sacchi, E. Tartaglia, R. Lionetti, M. Bibas, G. D’Offizi, E. Grilli, A. Antinori, C. Agrati

National Institute for Infectious Diseases L Spallanzani - IRCCS - Rome

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OP 14Sterol metabolism modulates susceptibility to HIV-1 Infection

I. Saulle1, S.V. Ibba1, C. Vittori1, C. Fenizia1, V. Mercurio1, F. Vichi2, S. Lo Caputo3, D. Trabattoni1, M. Clerici1,4, M. Biasin1

1Department of Biomedical and Clinical Sciences “L. Sacco”, University of Milan, Milan, Italy, 2S. Maria Annunziata Hospital, Florence, Italy, 3Clinica delle Malattie Infettive dell’Azienda Ospedaliero Universitaria Consorziale Policlinico di Bari, 4Don C. Gnocchi Foundation ONLUS, IRCCS, Milan, Italy

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OP 15Different amounts of activated or exhausted effector memory T cells among differentiated CD4+ or CD8+ T lymphocytes during primary, acute HIV infection

D. Lo Tartaro1, A. Camiro-Zúñiga2, S. Perez-Patrigeon2, A. Paolini1, M. Nasi1, C. Mussini1, A. Cossarizza1, S. De Biasi1

1Department of Medical and Surgical Sciences for Children and Adults, University of Modena and Reggio Emilia, Modena, Italy, 2National Institute for Medical Sciences and Nutrition "Salvador Zubirán", Tlalpan, Mexico City, Mexico

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OP 16HIV+ patients: modulating effects of antiretroviral therapy on cytokines' profile and microbiota composition

G. Nannini1, E. Russo1, V. Di Pilato2, M. Coppi1, F. Ricci3, E. Niccolai1, S. Tekle Kiros4, S. Baldi1, A. Bartoloni4,5, G.M. Rossolini1,6, A. Amedei1

1Department of Clinical and Experimental Medicine, University of Florence, Florence, Italy, 2Department of Surgical Sciences and Integrated Diagnostics, University of Genoa, Genoa, Italy, 3Department of Biomedical, Experimental and Clinical Sciences “Mario Serio” University of Florence, Florence, Italy, 4Infectious Disease Unit, Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy, 5Infectious and Tropical Disease Unit, Azienda Ospedaliero - Universitaria Careggi, Florence, Italy, 6Department of Experimental and Clinical Medicine, University of Florence, Italy; Clinical Microbiology and Virology Unit, Florence Careggi University Hospital, Florence, Italy

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OP 17Association between subclinical atherosclerosis and IFN-I response in HIV-1 infected patients

G. De Girolamo1, L. Santinelli1, C. Borrazzo1, C. Pinacchio1, G.P. Innocenti1, P. Vassalini1, E. Nelson Cavallari1, M,. Statzu2, F. Frasca2, M. Scordio2, M. Mancone3, G. Antonelli2, G. d’Ettorre1, C. Scagnolari2

1Department of Public Health and Infectious Diseases, Sapienza University of Rome, Rome, Italy, 2Department of Molecular Medicine, Laboratory of Virology, Sapienza University of Rome, Rome, Italy, 3Department of Cardiovascular, Respiratory, Nephrologic and Geriatric Sciences, Sapienza University of Rome, Rome, Italy

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OP 18p53/mir34a/SIRT1 loop and immune reconstitution relationship during chronic HIV infection

V. Bordoni, E. Tartaglia, A.Sacchi, A. Vergori, R. Gagliardini, A. Antinori, C. Agrati

National Institute for Infectious Diseases “L. Spallanzani” IRCCS

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OP 19Lower Immune Activation in Perinatally than in Horizontally HIV-Infected Adults

L. Taramasso1,2, D. Fenoglio3,4, A. Parodi5, F. Kalli3, A. Bandera1,2, C. Dentone6, T. Altosole3, M. Berruti6, S. Mora7, M. Giacomini3,7, G. Filaci3,5, A. Di Biagio6

1Infectious Diseases Unit, Department of Internal Medicine, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, University of Milan, Milan, Italy, 2MultidisciplinAry ResearCh in Health Science (MACH), Milan, Italy, 3Centre of Excellence for Biomedical Research (CEBR), University of Genova, Genoa, Italy, 4Department of Internal Medicine, University of Genoa- IRCCS Ospedale Policlinico San Martino, Genoa, Italy, 5Biotherapy Unit, IRCCS Policlinico San Martino Hospital, Genoa Italy, 6Department of Health Science (DISSAL), University of Genova and Infectious Disease Clinic, IRCCS Policlinico San Martino Hospital, Genoa, Italy, 7Department of Informatics, Bioengineering, Robotics and System Engineering (DIBRIS), University of Genoa, Genoa, Italy

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OP 20Microbiota Composition in HIV-Positive and HIV-Exposed Uninfected Pediatric Subjects

E. Merlini1, M. Ficara2, E.S. Cannizzo1, F. Ferrari2, C. Tincati1, L. Dotta3, C. Tagliabue4, A. Diana5, V. Camelli6, L. Iughetti2,7, A. d'Arminio Monforte1, M. Cellini2, G. Marchetti1 for the MIRROR Study Group

1Clinic of Infectious Diseases, Dept Health Sciences, University of Milan, ASST Santi Paolo e Carlo, Milan, Italy, 2Division of Paediatric Oncology-Haematology, Policlinico Hospital, Modena, Italy, 3Clinica Pediatrica and "A. Nocivelli" Institute for Molecular Medicine, Department of Clinical and Experimental Sciences, University of Brescia, Spedali Civili Hospital, Brescia, 4Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Milan, Italy, 5Department of Translational Medical Science, Section of Pediatrics, University Federico II, Naples, Italy, 6Dept of Sciences of Public Health and Pediatrics, University of Turin, Italy, 7Pediatric Unit, Azienda Ospedaliero-Universitaria Policlinico, Modena, Italy

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OP 21Switching to integrase inhibitors is not linked to weight increase in young adults and adolescents perinatally infected with HIV, results from a 10-years observational study

L. Taramasso1,2, A. Di Biagio3, F. Bovis4, F. Forlanini5, E. Albani5, R. Papaioannu3, V. Giacomet5

1Infectious Diseases Unit, Department of Internal Medicine, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, University of Milan, Milan, Italy, 2MultidisciplinAry ResearCh in Health Science (MACH), Milan, Italy, 3Infectious Diseases Clinic, Department of Health Sciences (DiSSal), University of Genoa, IRCCS Ospedale Policlinico San Martino, Genoa, Italy, 4Biostatistics Unit, Department of Health Sciences (DiSSal), University of Genoa, Italy, 5Clinic of Paediatrics, ASST Fatebenefratelli-Sacco, Milan, Italy

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OP 22An atypical case of HIV-1 elite controller: 15 years of follow up

C. Fimiani1, F. Falasca2, C. Cerboni2, H. Stabile2, C. Scagnolari2, O. Turriziani2

1Department of Internal Medicine and Infectious Disease, University Hospital Policlinico Umberto I, Rome, 2Department of Molecular Medicine, Sapienza University of Rome

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Oral Poster Clinical HIV

Chairs: M. Borderi, A. Ruggieri

OP 23Newly diagnosed HIV infected patients in Brescia, Northern Italy: epidemiological and clinical characteristics and possible targets of prevention and early diagnosis campaign

I. Izzo, G. Zuglian, C. Carriero, A. Celotti, E. Focà, M.A. Forleo, I. El Hamad, P. Nasta, M.C. Pezzoli, E. Quiros-Roldan, F. Castelli

University Department of Infectious and Tropical Diseases, University of Brescia and Spedali Civili General Hospital, Brescia, Italy

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OP 24Rosuvastatin decreases serum inflammatory markers and slows atherosclerosis progression rate in HIV-infected patients with metabolic syndrome

L. Calza, V. Colangeli, M. Borderi, D. Testi, A. Amedeo, M.A. Di Bari, C. Fulgaro, P. Viale

Department of Medical and Surgical Sciences, Unit of Infectious Diseases, S.Orsola-Malpighi Hospital, University of Bologna

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OP 25Durability of InSTI-based regimen in geriatric people living with HIV. Data from the Italian Multicenter GEPPO Cohort

E. Focà1, A. Calcagno2, S. Calza3, S. Renzetti3, A. Riva4, G.V. De Socio5, S. Piconi6, G. Orofino7, A. Chiesa1, G. Madeddu8, A. Cattelan9, S. Nozza10, J. Milic11, B.M. Celesia12, F. Castelli1, G. Di Perri2, G. Guaraldi11

1Division of Infectious and Tropical Diseases, University of Brescia and ASST Spedali Civili Hospital,Brescia, Italy, 2Unit of Infectious Diseases, Department of Medical Sciences, University of Torino, Torino, Italy, 3Unit of Biostatistics and Biomathematics & Unit of Bioinformatics, Department of Molecular and Translational Medicine, Università degli Studi di Brescia – Italy, 43rd Division of Infectious Diseases, University of Milano, Ospedale L. Sacco, Milano, Italy, 5Department of Infectious Diseases, Azienda Ospedaliero-Universitaria di Perugia, Perugia, Italy, 61st Division of Infectious Diseases Unit, University of Milano, Ospedale L. Sacco, Milano, Italy, 7Unit of Infectious Diseases, 'Divisione A', Ospedale Amedeo di Savoia, ASLTO2, Torino, Italy, 8Infectious and Tropical Diseases Unit, Department of Medical, Surgical and Experimental Sciences, University of Sassari, Sassari, Italy, 9Unit of Infectious Diseases, Department of Internal Medicine, Azienda Ospedaliero-Universitaria di Padova, Padova, Italy, 10Department of Infectious Diseases, San Raffaele Scientific Institute, Milano, Italy, 11University of Modena and Reggio Emilia, Department of Mother, Child and Adult Medicine and Surgical Science, Infectious Disease Clinic, Modena, Italy, 12Department of Clinical and Molecular Biomedicine, Division of Infectious Diseases, University of Catania, ARNAS Garibaldi, Catania, Italy

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OP 26Weight gain and body composition changes in people living with HIV treated with Integrase Strand Transfer Inhibitors: a longitudinal assessment with Bioimpedance Vectorial Analysis

M. Poliseno1, D.F. Bavaro1, P. Laghetti1, G. De Vita, N. de Gennaro1, S. Lo Caputo2, L. Monno1, G. Angarano1, A. Saracino1

1Department of Biomedical Sciences and Human Oncology, Clinic of Infectious Diseases, University of Bari Medical School, Bari, Italy, 2Clinic of Infectious Diseases University of Foggia, Foggia, Italy

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OP 27Transmitted drug resistance in newly diagnosed HIV-1-infected patients in a large teaching hospital of the Northern Italy

L. Calza2, M. Tamburello1, M. Borderi2, V. Colangeli2, D. Testi2, A. Amedeo2, M.C. Re1, I. Bon1

1Unit of Microbiology, University of Bologna (Italy), 2Unit of Infectious Diseases, University of Bologna (Italy)

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OP 28Same day treatment and rapid antiretroviral therapy introduction in a cohort of unselected newly-diagnosed HIV-positive individuals

G. Lapadula, M. Rossi, P. Vitiello, N. Squillace, A. Soria, P. Columpsi, F. Sabbatini, E. Colella, V. Cogliandro, A. Spolti, I. Beretta, A. Gambaro, G.M. Migliorino

Clinic of Infectious Diseases, “San Gerardo” Hospital, ASST-Monza, University of Milan-Bicocca, Italy

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OP 29Changes in homeostatic model assessment for insulin resistance (HOMA-IR) index in treated HIV-1 infected people on virological suppression

C. Muccini1, L. Galli2, A. Poli2, S. Bossolasco2, P. Cinque2, L. Fumagalli2, D. Canetti2, H. Hasson2, M. Ranzenigo1, M. Chiurlo1, A. Lazzarin2, A. Castagna1,2

1Vita-Salute San Raffaele University, Milan, Italy, 2Infectious Diseases, IRCCS San Raffaele Scientific Institute, Milan, Italy

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OP 30A descriptive analysis on dual regimens' discontinuations in a multicentre Italian cohort

D. Farinacci1, A. Ciccullo1, A. Dusina1, A. D’Angelillo1, D. Moschese1, A. Borghetti2, V. Borghi3, C. Mussini3, S. Di Giambenedetto1,2

1Istituto di Malattie Infettive, Università Cattolica del Sacro Cuore, Roma, Italy, 2Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Roma, Italy, 3Azienda Ospedaliero Universitaria di Modena, Clinica Malattie Infettive e Tropicali, Modena, Italy

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OP 31Virological response and resistance profile in highly treatment-experienced HIV-1 infected patients switching to dolutegravir plus boosted-darunavir in clinical practice

D. Armenia1,2, L. Fabeni3, R. Gagliardini4, V. Borghi5, G. Berno3, A. Vergori4, S. Cicalini4, C. Mussini5, A. Antinori4, F. Ceccherini-Silberstein1, C.F. Perno3, M.M. Santoro1

1Department of Experimental Medicine, University of Rome “Tor Vergata”, Rome, Italy, 2Saint Camillus International University of Health Sciences, Rome, Italy, 3Laboratory of Virology, INMI "Lazzaro Spallanzani"-IRCCS, Rome, Italy, 4Clinical Department, INMI "Lazzaro Spallanzani"-IRCCS, Rome, Italy, 5Clinic of Infectious Diseases, University Hospital, University of Modena and Reggio Emilia, Modena, Italy

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OP 32Does rapid initiation of ART at HIV diagnosis impact on virological response and retention in care? A single center experience (Brescia, Northern Italy)

A. Comelli, N. Gregori, A. Celotti, S. Renzetti, S. Calza, I. Izzo, C. Pezzoli, I. El Hamad, P. Nasta, M. Properzi, A. Chiesa, M. Degli Antoni, G. Faletti, B. Fumarola, E. Quiros-Roldan, F. Castelli, E. Focà

University Department of Infectious and Tropical Diseases, University of Brescia and Spedali Civili General Hospital, Brescia, Italy

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OP 33Efficacy and durability of dolutegravir- or darunavir-based regimens in ART-naïve AIDS- or late-presenter patients

M. Masini1, B. Rossetti2, A. Ciccullo3,4, V. Borghi5, F. Lagi6, A. Capetti7, M. Colafigli8, D. Moschese3,4, C. Mussini5, G. Sterrantino6, C. Picarelli3,4, F. Montagnani1, S. Di Giambenedetto3,4, M. Fabbiani2

1UOC Malattie Infettive e Tropicali, Dipartimento di Biotecnologie Mediche, Università di Siena, Siena, Italy, 2UOC Malattie Infettive e Tropicali, Azienda Ospedaliero-Universitaria Senese, Siena, Italy, 3Università Cattolica del Sacro Cuore, Dipartimento di Sicurezza e Bioetica Sezione Malattie Infettive, Rome, Italy, 4UOC Malattie Infettive, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy, 5Azienda Ospedaliero Universitaria di Modena, Clinica Malattie Infettive e Tropicali, Modena, Italy, 6Department of Experimental and Clinical Medicine, University of Florence, Florence Italy, 7Divisione di Malattie Infettive, Dipartimento di Malattie Infettive, Ospedale Universitario Luigi Sacco, Milano, Italy, 8Unità di Dermatologia Infettiva e Allergologia, Istituto S. Gallicano IRCCS, Roma, Italy

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OP 34Efficacy Safety and Tolerability of the switch from efavirenz/emtricitabine/tenofovir disoproxil on alternate days or continuous treatment to bictegravir/emtricitabine/tenofovir alafenamide in virologically suppressed HIV+ (EBONY Study)

M. Camici, A. Mondi, F. De Zottis, G. Passavanti, E. Grilli, A. Vergori, R. Gagliardini, S. Ottou, M.M. Plazzi, S. Cicalini, A. Antinori, R. Bellagamba

HIV/AIDS Clinical Unit, National Institute for Infectious Diseases Lazzaro Spallanzani IRCCS, Rome, Italy

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Oral Poster Clinical HIV II

Chairs: R. Bellagamba, V. Giacomet

OP 35Allogenic hematopoietic stem cell transplantation in HIV-positive recipients: a case series

C. Oltolini1, S. Piemontese2, R. Greco2, D. Clerici2, F. Giglio2, L. Galli1, M. Ripa1,3, B. Castiglioni1, C. Tassan Din1, S. Nozza1, C. Corti2, M. Bernardi2, J. Peccatori2, P. Scarpellini1, A. Lazzarin1, F. Ciceri2,3, A. Castagna1,3

1Clinic of Infectious Diseases, Division of Immunology, Transplantation and Infectious Diseases, IRCCS San Raffaele Scientific Institute, Milan, Italy, 2Hematology and Bone Marrow Transplantation, IRCCS San Raffaele Scientific Institute, Milan, Italy, 3University Vita-Salute San Raffaele, Milan, Italy

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OP 36Italian survey on clinicians' approach to Latent Tubercular Infection in people living with HIV

L. Caiazzo1,2, A. Calcagno3, F. Vignale1, M. Pontolillo1,4, A. Brandimarte4, A. Auricchio1,4, K. Falasca1,4, J.Vecchiet1,4

1Clinica di Malattie infettive, Chieti, 2Scuola di specializzazione in Malattie infettive e tropicali, Università politecnica delle Marche, Ancona, 3Unità di Malattie Infettive, Università di Torino, Torino, 4Scuola di specializzazione in Malattie infettive e tropicali, Università D'Annunzio, Chieti

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OP 37A poor immunological recovery is associated with non-AIDS-defining cancers in the era of HAART: a case-control study

A. Emiliozzi1,2, A. Ciccullo1, A. Dusina1, D. Moschese1, D. Farinacci1, C. Picarelli1, A. D’Angelillo1, S. Lamonica1, F. Lombardi1, G. Baldin1, A. Borghetti3, M. Fabbiani4, S. Di Giambenedetto1,3

1Università Cattolica del Sacro Cuore, Dipartimento di Sicurezza e Bioetica Sezione Malattie Infettive, Roma, Italy, 2UOC Malattie Infettive e Tropicali, Dipartimento di Biotecnologie Mediche, Università di Siena, Siena, Italy, 3Fondazione Policlinico Universitario A. Gemelli IRCCS, Roma Italia, UOC Malattie Infettive,4UOC Malattie Infettive e Tropicali, Azienda Ospedaliero-Universitaria Senese, Siena, Italy

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OP 38HPV infection in HIV+, MSM patients followed at a large HIV Clinic in Northern Italy

E. Asperges, V. Zuccaro, L. Pagnucco, R. Gulminetti, R. Maserati, R. Bruno

Infectious Disease Dept, Foundation IRCCS Policlinico “San Matteo” and University of Pavia

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OP 39Risk of multiple primary neoplasms and impact on survival of person living with HIV (PLWH)

V. Mazzotta1, P. Lorenzini1, A. Bandera2, A. Gori2, L. Sighinolfi3, S. Rusconi4, P. Bonfanti5, A. Cingolani6, G. Marchetti7, C. Mussini8, A. d’Arminio Monforte7, A. Antinori1 ICONA FOUNDATION STUDY GROUP

1HIV/AIDS Unit, INMI L. Spallanzani IRCCS, Roma, 2IRCCS Policlinico Ospedale Maggiore, University of Milano, 3Division of Infectious Disease, Hospital of Ferrara, Ferrara, 4ASST L. Sacco Hospital, University of Milano, 5Division of Infectious Disease, ASST Lecco, Lecco, 6Fondazione Policlinico A. Gemelli, Catholic University, Roma, 7ASST Santi Paolo e Carlo, University of Milano, 8Clinic of Infectious Disease, University hospital of Modena, Modena

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OP 40Development and standardization of a real time PCR for the quantification of HTLV-1 proviral load

A. Primavera1, A. Bertoldi1, I. Bon1, V. D’Urbano1, M. Tamburello1, L. Calza2, M.C. Re1, G. Gallinella3

1Microbiology Section, Department of Experimental, Diagnostic and Specialty Medicine, School of Medicine, University of Bologna, Italy, 2Clinics of Infectious Diseases, Department of Medical and Surgical Sciences, School of Medicine, University of Bologna, Italy, 3Department of Pharmacy and Biotechnology, University of Bologna, Bologna, Italy

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OP 41Is pretreatment HIV-1 integrase resistance increasing? A large Italian centre experience

D. Canetti1,2, L. Galli1, A. Poli1, N. Gianotti1, M. Ripa1,2, S. Nozza1, A. Bigoloni1, M. Guffanti1, L. Fumagalli1, M. Sampaolo1, E. Boeri1, A. Lazzarin1, A. Castagna1,2

1Clinic of Infectious Diseases, IRCCS San Raffaele, Milano, Italy, 2Clinic of Infectious Diseases, Vita-Salute San Raffaele University, Milano, Italy

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OP 42Association between low levels of HIV-1 DNA and HLA class I molecules in chronic HIV-1 infection

C. Muccini1, L. Galli2, A. Poli2, A. Bigoloni2, A. Mastrangelo1, E. Bruzzesi1, C. Uberti Foppa2, M. Guffanti2, G. Tambussi2, M. Cernuschi1, A. Lazzarin1, A. Castagna1,2

1Vita-Salute San Raffaele University, Milan, Italy, 2Infectious Diseases, IRCCS San Raffaele Scientific Institute, Milan, Italy

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OP 43Evolving epidemiology of HIV/AIDS in Campania Region, 2008-19: is HIV/AIDS population in Campania different?

F.M. Fusco1, A. Menna2, A. Galano2, L. Anna2, A. Mariniello2, M. De Cenzo2, S. Mascolo3, M. Sardo4, R. Viglietti1, G. Parrella1, O. Tambaro1, V. Iodice1, M.A. Pisaturo1, G. Di Flumeri1, E. Manzillo4, V. Esposito3, A. Chirianni1, V. Sangiovanni1

1UOC Infezioni Sistemiche e dell’Immunodepresso, P.O. “D. Cotugno”, Azienda Ospedaliera dei Colli, Naples, Italy, 2Servizio Ospedalizzazione Domiciliare, P.O. “D. Cotugno”, Azienda Ospedaliera dei Colli, Naples, Italy, 3UOC Immunodeficienze e Malattie Infettive di Genere, P.O. “D. Cotugno”, Azienda Ospedaliera dei Colli, Naples, Italy, 4U.O.C. Immunodeficienze e malattie dell’immigrazione, P.O. “D. Cotugno”, Azienda Ospedaliera dei Colli, Naples, Italy

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OP 44Impact of boosted vs unboosted antiretroviral regimen on Dolutegravir plasma and intracellular pharmacokinetics

M. Ferrara, C. Alcantarini, A. Lazzaro, A. Di Stefano, S. Biffi, M. Trunfio, M. Tettoni, V. Avataneo, A. Ianniello, E. De Vivo, A. De Nicolò, A. D’Avolio, A. Calcagno, G.D. Perri, S. Bonora

Unit of Infectious Diseases, Department of Medical Sciences, University of Torino, Torino

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Oral Poster Comorbidities

Chairs: F. Carli, P. Maggi, I. Maida

OP 45Inflammatory and neurometabolite changes among patients switching away from efavirenz and their correlation with neurotoxicity: results from the sub-study of a randomized controlled trial

I. Baldisserotto1, E. Bresciani1, D.P. Bernasconi1, M. Rossi2, E. Focà3, A. di Biagio4, F. Bai5, F. Castelli3, A. Calcagno6, A. d’Arminio Monforte7, A. Torsello1, G.M. Migliorino2, G. Lapadula2 for the Swear Study Group

1University of Milan-Bicocca, Milan, Italy, 2San Gerardo Hospital, Monza, Italy, 3University of Brescia, Brescia, Italy, 4San Martino Hospital, Genoa, Italy, 5San Paolo Hospital, Milan, Italy, 6University of Turin, Turin, Italy, 7University of Milan, Milan, Italy

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OP 46Contribution of INSTI, BMI, physical activity or caloric intake to weight gain in PLWH

G. Guaraldi1, J. Milic1, G. Dolci1, A. Malagoli1, F. Carli1, M. Menozzi1, I. Franconi1, A. Raimondi1, G. Ciusa1, V. Masi1, M. Belli1, S. Guaraldi1, C. Mussini1, T.T. Brown2, J.E. Lake3, K. Erlandson4

1Infectious Disease Unit, University of Modena and Reggio Emilia, Modena, Italy, 2Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, 3David Geffen School of Medicine, University of California, Los Angeles, CA, USA, 4University of Colorado-Anschutz Medical Center, Aurora, Colorado

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OP 47Cerebrospinal Fluid CXCL13 as a marker of Intrathecal Immunoglobulin Synthesis and Immune-activation in treatment-naïve People Living with HIV

M. Trunfio1, L. Mighetto2, E. Borgogno1, C. Atzori3, A. Di Stefano1, M. Nigra2, D. Imperiale3, S. Bonora1, G. Di Perri1, A. Calcagno1

1Infectious Diseases unit, Amedeo di Savoia hospital, University of Torino, Torino, Italy, 2Diagnostic Laboratory unit, Maria Vittoria hospital, ASL Città di Torino, Torino, Italy, 3Neurology unit, Maria Vittoria hospital, ASL Città di Torino, Torino, Italy

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OP 48Evaluation of the association between cognitive performance and HAND diagnosis with the cognitive reserve in naïve HIV-infected patients

A.C. Brita, A. Vergori, G. Passavanti,P. Lorenzini, S. Cicalini, R. Gagliardini, R. Bellagamba, E. Grilli, A. Mondi, S. Grisetti, V. Mazzotta, F. Baldini, A. Giannetti, A. Antinori, C. Pinnetti

National Institute for Infectious Diseases, IRCCS, L. Spallanzani-HIV/AIDS Unit,Rome,Italy

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OP 49Are Low vitamin D plasma levels associated with intrathecal immuneactivation in PLWH?

A. Vergori1, V. Bordoni2, P. Lorenzini1, G. Passavanti1, S. Notari2, V. Mazzotta1, S. Cicalini1, A. Giannetti1, F. Forbici3, C. Agrati2, A. Antinori1 ,C. Pinnetti1

1HIV/AIDS Unit, National Institute for Infectious Diseases L.Spallanzani, IRCCS, 2Cellular immunology and Pharmacology Unit, National Institute for Infectious Diseases L.Spallanzani, IRCCS, 3Virology Unit,National Institute for Infectious Diseases L. Spallanzani, IRCCS

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OP 50Gender differences in neurocognitive functions in PLWK

V. Delle Donne1, N. Ciccarelli2, V. Massaroni1, F. Lombardi1, C. Picarelli1, A. Borghetti1, A. Emiliozzi1, A. Dusina1, A. Ciccullo1, D. Moschese1, G. Baldin1,5, D. Farinacci1, S. Di Giambenedetto1,4, M.Fabbiani3

1Università Cattolica del Sacro Cuore, Roma Italia, Istituto di Clinica Malattie Infettive, 2Dipartimento di Psicologia, Università Cattolica di Milano, 3UOC Malattie Infettive e Tropicali, Azienda Ospedaliero-Universitaria Senese, Siena, Italy, 4Fondazione Policlinico Universitario A. Gemelli IRCCS, Roma Italia, UOC malattie infettive, 5Mater Olbia Hospital, Olbia, Italy

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OP 51Menopause in aging women living with HIV: changes in bone mineral density and trabecular bone score

D. Morini1, A. Malagoli2, J. Milic2,3, F. Carli2, A. Raimondi2, I. Franconi2, C. Mussini2, V. Rochira4, G. Guaraldi2

1University of Modena and Reggio Emilia, Modena, Italy, 2Modena HIV Metabolic Clinic, University of Modena and Reggio Emilia, Italy, 3Clinical and Experimental Medicine PhD Program, University of Modena and Reggio Emilia, Modena, Italy, 4Unit of Endocrinology, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Modena, Italy

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OP 52NAFLD phenotype and prevalence across the menopause spectrum in women with HIV

J. Milic1, A. Cervo2, A. Malagoli1, V. Menozzi1, D. Morini1, F. Carli1, A. Raimondi1, M. Menozzi1, I. Franconi1, C. Mussini1, G. Sebastiani3, G. Guaraldi1

1University of Modena and Reggio Emilia, 2Infectious Diseases Unit, PROMISE, University of Palermo, Palermo, Italy, 3Chronic Viral Illness Service, McGill University Health Centre, Montreal, Canada

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OP 53Incidence of diabetes in a cohort of PLWH people living with HIV in Perugia

M. Nofri1, E. Schiaroli1, S. Parrettini2, M. Cavallo2, V. Bianconi 3, V.G. De Socio1, R. Calafiore2, D. Francisci1

1Unit of Infectious Diseases, Department of Medicine, University of Perugia, Perugia, Italy, 2Division of Endocrinology and Metabolism, Department of Medicine,University of Perugia, Perugia, Italy, 3Unit of Internal Medicine, Department of Medicine, University of Perugia, Perugia, Italy

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OP 54Standard vs higher dose of Rifampicin in patients with tuberculosis: a meta-analysis

V. Gentile1, L. Onorato1, A. Russo1, L. Alessio2, G. DiCaprio2, N. Coppola1

1Department of Mental Health and Public Medicine – Infectious Diseases Unit, University of Campania Luigi Vanvitelli; Napoli, 2Infectious Diseases Unit, Sant' Anna e San Sebastiano Hospital; Caserta

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Oral Poster Hepatitis and Coinfections

Chairs: O. Armignacco, M. Massari, C. Sagnelli

OP 55Rapid Detection of Mycobacterium tuberculosis DNA in pulmonary and extrapulmonary paraffinized samples by ddPCR

M. Antonello1, R. Scutari2, C. Lauricella3, S. Renica1, V. Motta3, S. Torri4, S.M. Veronese3, L.R. Codecasa5, E. Bonoldi3, C. Vismara4, A. Bandera6, E. Mazzola4, A. Gori6, C.F.Perno1,4, C. Alteri1 on behalf of IFALT study group

1Department of Oncology and Hemato-Oncology, University of Milan, Milan, 2Department of Experimental Medicine, University of Rome "Tor Vergata", Rome, 3Department of Pathology, ASST Grande Ospedale Metropolitano Niguarda, Milan, 4Unit of Microbiology, Department of Chemical-clinical and Microbiology Analyses, ASST Grande Ospedale Metropolitano Niguarda, Milan, 5Regional TB Reference Centre, Villa Marelli Institute, ASST Grande Ospedale Metropolitano Niguarda, Milan, 6Infectious Unit, IRCCS Policlinico Maggiore, Milan

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OP 56Pharyngeal contamination is a major driver for sexually transmitted infections epidemic in Men who have Sex with Men

R. Rossotti1, C. Baiguera1, C. Vismara2, M. Merli1, A.Nava2, S. Chiappetta1, M.C. Moioli1, D. Fanti2, L.G. Chianura1, D. Motta1, C.F. Perno2,3, M. Puoti1

1Department of Infectious Diseases, ASST Grande Ospedale Metropolitano Niguarda, Milan, 2Chemical-Clinical and Microbiological Analysis, ASST Grande Ospedale Metropolitano Niguarda, Milan, 3Department of Oncology and Hemato-Oncology, Università degli Studi di Milano, Milan

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OP 57HCV infection in PWUD: a microelimination intervention in Rome

C. Taibi1, I. Luzzitelli1, A.R. Garbuglia2, L. Rapisarda3, G. Monacelli3, U. Visco Comandini1, R. Lionetti1, E. Girardi4, G. D'Offizi1

1Hepatology and Infectious Disease Department, National Institute for Infectious Diseases “Lazzaro Spallanzani” IRCCS, Rome, 2Virology Unit, National Institute for Infectious Diseases “Lazzaro Spallanzani” IRCCS, Rome, 3Service for Addictions Department. ASL RM3, Rome, 4Epidemiology Unit, National Institute for Infectious Diseases “Lazzaro Spallanzani” IRCCS, Rome

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OP 58Direct-acting antiviral based treatment for HCV-infected persons who inject drugs: a multi-centre real-life study

L. Onorato1, V. Messina1, G. Di Caprio1, A. Russo1, C. Caruso2, V. Rosato3, E. Claar3, V. Iovinella2, N. Coppola4

1Infectious Diseases Unit, AORN Sant’Anna e San Sebastiano, Caserta, Italy, 2Department of Internal Medicine, San Paolo Hospital, Naples, Italy, 3Hepatology Unit, "Villa Betania" Evangelical Hospital, Naples, Italy, 4Department of Mental Health and Public Medicine, Section of Infectious Diseases, University of Campania L. Vanvitelli, Naples, Italy

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OP 59Are Non-Injecting Drug Users at risk of HCV-infection? Data from the San Patrignano cohort

A. Boschini1, P. Piselli2, R. Poletti1, M. Begnini1, P. Ottogalli1, C. Cimaglia2, P. Parracino2, E. Girardi2

1Comunità San Patrignano (Rimini), 2INMI “L. Spallanzani” IRCCS, Rome

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OP 60Real Life DAAs in a large cohort of people who use drugs with hepatitis C virus infection in Tor Vergata Hospital in Rome: adherence, efficacy and reinfections of a key population

T. Mulas, E. Teti, L. Foroghi, G. De Simone, L. Campogiani, L. Ferrari, C. Stingone, M. De Masi, L. Coppola, M. Compagno, M. Iannetta, L. Sarmati, M. Andreoni

Infectious Diseases Clinic, Tor Vergata Hospital, Rome, Italy

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OP 61Effects of HCV eradication on liver function in haemophilic HIV/HCV co-infected patients

V. Castelli1, L. Taramasso1, F. Portunato2, G. Bozzi1, A. Gori1, A. Bandera1, A. Muscatello1, M.E. Mancuso3

1Infectious Diseases Unit, Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico, Milano, 2Infectious Diseases Unit, Azienda Ospedaliera Universitaria Federico II, Napoli, 3Angelo Bianchi Bonomi Hemophilia and Thrombosis Center, Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico, Milano

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OP 62Virological patterns of HCV-patients with failure to second generation direct-acting antivirals

M. Starace1, M. Pisaturo1, C. Minichini1, S. De Pascalis1, M. Macera1, L. Occhiello1, A. Di Fraia1, L. Alessio2, V. Messina2, E. Claar3, T. Ascione4, A. Marrone5, V. Rosato3, I. Gentile6, V. Iovinella7, L. Fontanella8, G. D’Adamo9, R. Santoro10, G.B. Gaeta1, N. Coppola1

1Infectious Diseases Unit, Department of Mental and Physical Health and Preventive Medicine, University L. Vanvitelli, Naples, Italy, 2Infectious Diseases Unit, AO Caserta, Caserta, Italy, 3Internal Medicine Unit, Evangelical Hospital Villa Betania Naples, Italy, 4Internal Medicine Unit, University L. Vanvitelli, Marcianise (CE), Italy , 5Internal Medicine, University of Campania L. Vanvitelli, 6Infectious Diseases Unit, University Federico II, Naples, Italy, 7Internal Medicine Unit, P.O. S.Paolo - ASL Napoli 1, Naples, Italy, 8Internal Medicine Unit, AO Madonna del Buon Consiglio FATEBENEFRATELLI, Naples, Italy, 9Internal Medicine Unit, P.O. Umberto I Nocera Inferiore, 10Internal Medicine and Hepatology Unit, PO G. Da Procida-AOU- San Giovanni e Ruggi D'Aragona, University of Salerno

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OP 63Advanced liver disease outcomes after Hepatitis C viral eradication according to Human Immunodeficiency Virus coinfection in PITER cohort

M.G. Quaranta1, L. Ferrigno1, M. Monti2, R. Filomia3, E. Biliotti4, A. Iannone5, G. Migliorino6, B. Coco7, F. Morisco8, M. Vinci9, R. D'Ambrosio10, L. Chemello11, M. Massari12, D. Ieluzzi13, F.P. Russo14, P. Blanc15, G. Verucchi16, M. Puoti17, M.G. Rumi18, F. Barbaro19, T.A. Santantonio20, A. Federico21, L. Chessa22, I. Gentile23, M. Zuin24, G. Parruti25, G. Morsica26, L.A. Kondili1 on behalf of PITER Collaborating Group*

1Center for Global Health, Istituto Superiore di Sanità, Rome, 2Interdepartmental Centre MASVE, University of Florence, Florence, 3Division of Clinical and Molecular Hepatology, University Hospital of Messina, Messina, 4Hepatology Unit, Department of Clinical Medicine, Sapienza University, Rome, 5Department of Emergency and Organ Transplantation, Gastroenterology Unit, University of Bari, Bari, 6Division of Infectious Diseases, San Gerardo Hospital, Monza, 7Hepatology and Liver Physiopathology Laboratory and Internal Medicine, Department of Clinical and Experimental Medicine, University Hospital of Pisa, Pisa, 8Department of Clinical Medicine and Surgery, Federico II University, Naples, 9Departement of Hepatology and Gastroenterology, Niguarda Hospital, Milan, 10Pathophysiology and Transplantation Department, Gastroenterology and Hepatology, CRC AM e A Migliavacca Center for Liver Diseases, Fondazione Ca' Granda IRCCS Ospedale Maggiore Policlinico, University of Milan, Milan, 11Department of Medicine, University Hospital of Padua, Padua, 12Infectious Diseases, Azienda Unità Sanitaria Locale – IRCCS di Reggio Emilia, Reggio Emilia, 13Clinical Unit of Gastroenterology, University Hospital of Verona, Verona, 14Gastroenterology Unit, Department of Surgery, Oncology and Gastroenterology, University of Padua, Padua, 15Infectious Disease Unit, Santa Maria Annunziata Hospital, Florence, 16Department of Medical and Surgical Sciences, Clinic of Infectious Diseases and Microbiology Unit, Alma Mater Studiorum Bologna University, Bologna, 17Department of Infectious Disease, Niguarda Hospital, Milan, 18Hepatology Unit, San Giuseppe Hospital, University of Milan, Milan, 19Infectious and Tropical Diseases Unit, Azienda Ospedaliera di Padova, Padua, 20Infectious Diseases, Ospedali Riuniti, Foggia, 21Department of Precision Medicine, University of Campania "Luigi Vanvitelli", Naples, 22Liver Unit, University Hospital, Monserrato, Cagliari, 23Department of Clinical Medicine and Surgery, Federico II University, Naples, 24Department of Health Sciences, San Paolo Hospital, University of Milan, Milan, 25Infectious Disease Unit, Spirito Santo General Hospital, Pescara, 26Department of Infectious Diseases, San Raffaele Hospital, Milan, *available at www.progettopiter.it

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OP 64The combination of accurate serological and virological HBV markers can help to predict the occurrence of HBV reactivation and to optimize prophylaxis duration in HBsAg-negative/anti-HBc-positive patients with oncohematological diseases

R. Salpini1, C. Cerva2, M. Alkhatib1, L. Piermatteo1, A. Battisti1, V. Malagnino2, L Fabeni1, M.L. Cantonetti3, W. Arcese3, F. Ceccherini-Silberstein1, C.F. Perno4, M. Andreoni2, L. Sarmati2, V. Svicher1

1Department of Experimental Medicine, Tor Vergata University, Rome, Italy, 2Clinical Infectious Disease, Department of System Medicine, Tor Vergata University, Rome, Italy, 3Department of Hematology, Stem Cell Transplant Unit, Tor Vergata University, Rome, Italy, 4Department of Oncology and Haemato-oncology, University of Milan

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OP 65HBV and HDV infection in immigrants living in South Italy: epidemiological and virological characteristics

L. Onorato2, M. Pisaturo2,6, C. Sagnelli2,4, L. Alessio1,4, C. Monari1, L. Gualdieri5, C. Minichini2, G. Di Caprio1, M. Starace2, M. Caroprese1, L. Occhiello1, G. Scotto6, M. Macera2, E. Sagnelli2, N. Coppola1,2

1UOC di Malattie Infetttive, AORN Sant'Anna e San Sebastiano, Caserta, 2Sezione di Malattie Infettive, Dipartimento di Salute Mentale e Medicina Pubblica, Università della Campania Luigi Vanvitelli, Napoli, 3Centro di Accoglienza "La tenda di Abramo", Caserta, 4Centro Suore Missionarie della Carità, Napoli, 5Centro per la Tutela della Salute degli Immigrati, Napoli, 6Centro sociale ex canapificio Caserta, 7UOC di Malattie Infettive, Foggia

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OP 66HEV infection as an emergent public health issue: is it a concern for Italian blood donors?

L. Colagrossi1, M. Mercuri2, A. Nava2, E. Matarazzo1, D. Campisi2, C.F. Perno1,2, D. Fanti2

1Residency in Microbiology and Virology, Università degli Studi di Milano, Milan; 2Chemical-clinical and Microbiological Analysis, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy

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Oral Poster Social Science and Prevention

Chairs: S. Babudieri, B.M. Celesia, M.G. Di Benedetto

OP 67HIV SelfTesting: a survey of self-tests availability in Italian Pharmacies

M. Maffeo1,2, M.L. Cosmaro2, M. Kall3, S. Nash3

1Scuola di Specializzazione in Igiene e Medicina Preventiva - Università degli Studi Milano Statale, 2Fondazione Lega Italiana per la Lotta contro l’AIDS - LILA Milano, 3Public Health England

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OP 68Testing MSM in cruising venues

D. Zagato1, A. Andolina1,L. Beltrami1, A. Bianchi1, A. Brambilla1, G. Calcagno1, D. Calzavara2, M. Carbonara2, D. Deserti2, A.J. Gallucci2, V. Gambini1, E. Garavaglia2, M.Gucciardi1, V. LaMonica1, S. Lolli1, L. Londei1, F. Maddaloni1, M. Manfredini1, G.M. Mattioli2, V. Nicotera1, D. Pennisi1, P. Peruggia1, A. Pezzotti1, M. Pierini1, C. Romero1, R. Rossotti1, A. Ruggeri2, P. Testoni1, L. Valpreda1, P. Vinti1, A.Ünlü1, M. Cernuschi1

1ASA Associazione Solidarietà AIDS, Milan, 2CIG-Arcigay, Milano

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OP 69Behavioral aspects of MSM tested in community-based settings in 5 cities

M. Breveglieri1, P. Guarino2, A. Bignardi3, D. Pavia3, D. Calzavara4, M. Costacurta2, D. Deserti 4, F. Angeli 5, M. Marocco1, G. Corradini6

1Arcigay, Associazione LGBTI+ Italiana, 2Arcigay Padova, 3Arcigay Modena, 4Arcigay Milano, 5Arcigay Roma, 6Arcigay Verona

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OP 70Pre-exposure prophylaxis in Modena: a wide spread of sexually transmitted infections among users attending the dedicated outpatient Clinic

C. Rogati1, C.G. Cuomo1, A. Raimondi1, M. Tutone1, E. Bacca1, B. Beghetto1, E. Roncaglia1, G. Nardini1, V. Borghi1, G. Guaraldi1, M. Coppini1, C. Mussini1

1Clinic of Infectious Diseases, University of Modena and Reggio Emilia, Modena, Italy, 2Clinic of Dermatology, University of Modena and Reggio Emilia, Modena, Italy

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OP 71Prevalence and risk factors for HPV anal infection in PrEP users: implications for vaccination policy

R. Rossotti1, C. Baiguera1, A. Nava2, M. Merli1, D. Fanti2, S. Chiappetta1, M.C. Moioli1, L. Colagrossi2, L.G. Chianura1, D. Motta1, C.F. Perno2,3, M. Puoti1

1Department of Infectious Diseases, ASST Grande Ospedale Metropolitano Niguarda, Milan, 2Chemical-Clinical and Microbiological Analysis, ASST Grande Ospedale Metropolitano Niguarda, Milan, 3Department of Oncology and Hemato-Oncology, Università degli Studi di Milano, Milan

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OP 72NEETagers for the prevention of HIV and AIDS

V. Corallino, M. Ramadori

Anlaids Umbria Onlus, Corciano (PG)

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OP 73Clinical research integrated with narrative medicine to understand living and coping with HIV: TMC114FD1HTX4011 - DIAMANTE study

A. Antinori1, A. Vergori1, D. Ripamonti2, D. Valenti3, V. Esposito3, M.A. Carleo4, S. Rusconi5, E. Manzillo6, T. Pizzella6, G. Orofino7, G. Madeddu8, A. Cappuccio9, L. Reale9, M.G. Marini9, A. Uglietti10, R. Termini10, M. Portaro10, D. Mancusi10

1HIV/AIDS Unit, National Institute for Infectious Diseases "Lazzaro Spallanzani" IRCCS, Roma, Italy, 2Infectious Diseases Unit, Papa Giovanni XXIII Hospital, Bergamo, Italy
3FROM Research Foundation, Papa Giovanni XXIII Hospital, Bergamo, Italy, 4Immunodeficiencies and Gender Infectious Diseases Unit, Department of Infectious Disease and Infectious Emergencies, Cotugno Hospital, Naples, Italy, 5Infectious Diseases Unit, DIBIC Luigi Sacco, University of Milan, Italy, 6A.O.R.N. Cotugno VIII Divisione di Malattie Infettive Napoli, Italy, 7Amedeo di Savoia Hospital Unit of Infectious Diseases Torino, Italy, 8University of Sassari, Department of Medical, Surgical and Experimental Sciences, Unit of Infectious Diseases Sassari Italy, 9Fondazione ISTUD, Milan, Italy, 10Medical Affairs Department, Infectious Diseases, Janssen-Cilag SpA, Cologno Monzese, Italy

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OP 74Women and HIV in prison setting: a data up date from the Italian ROSE network

E. Rastrelli1, 2, R. Ranieri2,3, S. Marcellini2,4, E. Pontali2,5, R. Bergamaschi6, V. Esposito7, V. Rizzo7, A. Bascià8, M.R. Attianese9, A. Tartaglia10, F. Campanale11, L. Rapisarda12,V. Fiore13, T. Prestileo2,14, G. Leo2,15, M. Giuliano2,15, O. Mollaretti2,15, R. Marocco16, M. Pontolillo17, F. Vignale17, A. Lucarini18, G. Pugliese19, R. Giuliani3, A.M. Ialungo1,2, S. Dell’Isola1,2, L. Testa1,2, Lucania2,20, S. Babudieri2,13,G. Starnini1,2

1U.O.C. Medicina Protetta-Malattie Infettive, Ospedale Belcolle, Viterbo, 2SIMSPe (Società Italiana di Medicina e Sanità Penitenziaria), 3Azienda Ospedaliera Santi Paolo e Carlo Unità di Malattie Infettive, Università di Milano Unità di Malattie Infettive in Ambito Penitenziario, Milano, 4Casa Circondariale Rebibbia Femminile, Roma, 5Unità di Malattie Infettive, Ospedale Galliera, Genova, 6Casa Circondariale Pesaro, 7UOC Immunodeficienze e Malattie Infettive di Genere, Ospedale Cotugno, Napoli, 8Distretto Socio Sanitaria ASL Lecce, Poliambulatorio “Cittadella della Salute, 9ASL Salerno CC Salerno, 10Ambulatorio Malattie Infettive ASL Foggia, 11Specialistica Ambulatoriale ASL Bat, 12CC Catania, 13Unità di Malattie Infettive, Università di Sassari, Sassari, 14ARNAS, Ospedale Civico-Benefratelli Palermo, Palermo, 15Unità di Malattie Infettive, Ospedale Amedeo di Savoia, Torino Casa Circondariale "G. Panzera", 16Unità di Malattie Infettive, Università La Sapienza, Ospedale S. M., Latina, 17Clinica di Malattie Infettive, Dipartimento di Medicina ed Scienze dell'Invecchiamento, Università G. d'Annunzio, Chieti, 18Casa Circondariale di Perugia «Capanne», 19Casa Circondariale Avellino, 20Reggio Calabria ASP Reggio Calabria – Presidio I.P. RC “Panzera” e “Arghillà"

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OP 75First-year experience of an HIV clinic-based stop-smoking service

V. Spagnuolo1,2, E. Lombardi2, A. Poli2, S. Bossolasco2, C. Raddato1, A. Castagna1,2, A. Lazzarin2, N. Gianotti2

1School of Medicine and Surgery, Vita-Salute San Raffaele University, Milan, 2Division of Infectious Diseases, San Raffaele Scientific Institute, Milan

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OP 76Psychiatric disturbances are common in PrEP users: an analysis of comorbidities and comedications in real life

R. Rossotti, C. Baiguera, M. Colaneri, M. Merli, S. Chiappetta, M.C. Moioli, L.G. Chianura, D. Motta, M. Puoti

Department of Infectious Diseases, ASST Grande Ospedale Metropolitano Niguarda

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Oral Poster Virology and Pharmacology

Chairs: R. Cavallo, S. Parisi

OP 77The HIV-1 provirus excised by CRISPR/Cas9 may be integrated back into the cell genome in presence of the viral integrase

M. Lai1,2, P. Quaranta1, F. Maggi1,3, M. Sgarbanti4, O. Turriziani7, G. Freer1, G. Antonelli7, J.L. Heeney2, M. Pistello1,3

1Retrovirus Center and Virology Section, Department of Translational Research and New Technologies in Medicine and Surgery, University of Pisa, Pisa, Italy, 2Laboratory of Viral Zoonotics, Department of Veterinary Medicine, University of Cambridge, Cambridge, United Kingdom, 3Virology Unit, Pisa University Hospital, Pisa, Italy, 4National Institute of Health, Rome, Italy, 5Pharmacology Unit, Department of Clinical and Experimental Medicine, University of Pisa, Italy, 6Hematology Unit, Department of Clinical and Experimental Medicine, University of Pisa, Italy, 7Laboratory of Virology and Pasteur Institute-Cenci Bolognetti Foundation, Department of Molecular Medicine, Sapienza University of Rome, Rome, Italy

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OP 78Analysis of HIV latency establishment and maintenance in CD4 T cells stimulated with IL-15

G.M. Butta1,2, G. Bozzi3, G. Copaloni2, G. Gallo2, M. Crosti1, M. Mancino1, L. Taramasso3,4,5, A. Muscatello3, A. Gori3,4,5, R. De Francesco1,2, A. Bandera3,4,5, L. Manganaro1,3

1INGM-Istituto Nazionale di Genetica Molecolare, Virology, Milan, Italy, 2Università degli Studi di Milano, Department of Pharmacological and Biomolecular Sciences, Milan, 3Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Infectious Diseases Unit, Department of Internal Medicine, Milan, Italy, 4Centre for Multidisciplinary Research in Helath Science (MACH), 5Università degli Studi di Milano, Department of Pathophysiology and Transplantation, Milan, Italy. Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico

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OP 79Phylogenetic analyses applied to the study of transmission variants and their evolution in a HIV-1 positive couple

A. Lai, V. Giacomet, A. Bergna1, G.V. Zuccotti2, G. Zehender1, M. Clerici3,4, D. Trabattoni1, C. Fenizia3

1Department of Biomedical and Clinical Sciences, University of Milan, Milan, 2Clinic of Pediatrics, ASST Fatebenefratelli-Sacco, Sacco Clinical Sciences Institute, Milan, 3Department of Pathophysiology and Transplantation, University of Milan, Milan, 4IRCCS Fondazione Don Carlo Gnocchi, Milan
ǂThe authors consider that the first two authors should be regarded as joint First Authors

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OP 80Creation of an Italian HIV DNA Network for the validation and clinical use of HIV-1 DNA quantification assays

I. Vicenti1, F. Dragoni1, A. Giannini1, A. Callegaro2, G. Napolitano2, O. Turriziani3, D. Di Carlo3, S.Giambenedetto4,14, F. Lombardi4, S. Belmonti4, F. Ceccherini-Silberstein5, R. Scutari5, C. Alteri5,6, A. Lai7, A. Bergna7, S. Racca8, A. Ardemagni8, A. Casabianca9, C. Orlandi9, I. Bon10, A. Bertoldi10, P. Bagnarelli11, L. Di Sante11, I. Abbate12, G. Rozera12, M.R.Capobianchi12, S. Paolucci13, G. Campanini13, F. Saladini1, M. Zazzi1

1Department of Medical Biotechnologies, University of Siena, Siena, 2Microbiology and Virology Laboratory, ASST Papa Giovanni XXIII, Bergamo, 3Department of Molecular Medicine, Sapienza University of Rome, Rome, 4Department of Safety and Bioethics, Infectious Disease Section, Catholic University of Sacred Heart, Rome, 5Department of Experimental Medicine, University of Rome Tor Vergata, Rome, 6Department of Oncology and Hemato-oncology, University of Milan, Milan, 7Department of Biomedical and Clinical Sciences L. Sacco, University of Milan, Milan, 8Laboratory of Microbiology and Virology, IRCCS San Raffaele Scientific Institute, Milan, 9Department of Biomolecular Sciences, University of Urbino "Carlo Bo", Urbino, PU, 10Microbiology Section, Department of Experimental, Diagnostic and Specialty Medicine, School of Medicine, University of Bologna, Bologna, 11Virology Unit, Department of Biomedical Sciences and Public Health, Polytechnic University of Marche, Ancona, 12Virology and Biosafety Laboratories Unit, National Institute for Infectious Diseases IRCCS L. Spallanzani, Rome, 13Molecular Virology Unit, Microbiology and Virology Department, Fondazione IRCCS Policlinico San Matteo, Pavia, 14Fondazione Policlinico Universitario A. Gemelli IRCCS, UOC Infectious Disease Rome

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OP 81Initial characterization of elements detected and quantified exclusively on the basis of LTR region by Aptima HIV-1 Quant Dx dual-target assay in plasma of HIV-positive patients

A. Amendola, G. Sberna, M.R. Capobianchi

National Institute for Infectious Diseases L. Spallanzani IRCCS, Rome, Italy

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OP 82Stable total HIV-DNA after 1 year on switch to TAF-based regimens in real world data

C. Alteri1, A. Cozzi-Lepri2, R. Scutari3, Y. Bouba3, E.S. Cannizzo4, A. Tavelli5, M. Prato6, F. Bai4, A. Antinori7, A. d’Arminio Monforte4, F. Ceccherini-Silberstein3, G. Marchetti4
*on behalf of Icona and TAF-Icona Study Groups

1Dept. of Oncology and Hemato-Oncology, University of Milan, Milan, Italy, 2Centre for Clinical Research, Epidemiology, Modelling and Evaluation (CREME) Institute for Global Health UCL, London, UK, 3Dept. of Experimental Medicine, University of Tor Vergata, Rome, Italy, 4Clinic of Infectious Diseases, Dept Health Sciences, University of Milan, ASST Santi Paolo e Carlo, Milan, Italy, 5Icona Foundation, Milan, Italy, 6Unit of Infectious Diseases, Santa Maria Annunziata Hospital, Florence, Italy, 7HIV/AIDS Clinical Unit, National Institute for Infectious Diseases Lazzaro Spallanzani IRCCS, Rome, Italy

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OP 83HIV-1 RNA and DNA mutational load in HTE patients with MDR virus: a tool for deciding OBR?

M.M. Santoro1, D. Armenia1,2, M.C. Bellocchi1, L. Carioti1, L. Galli3, A. Galli3, R. Scutari1, E. Salsi4, C. Mussini5, G. Sterrantino6, L. Calza7, B. Rossetti8, M. Zazzi9, A. Castagna3,10, on behalf of the PRESTIGIO Registry Study Group

1Department of Experimental Medicine, University of Rome "Tor Vergata", Rome, 2Saint Camillus International University of Health Sciences, Rome, 3Clinic of Infectious Diseases, Istituto Scientifico San Raffaele, Milano, 4Azienda Ospedaliero-Universitaria Parma, 5Malattie Infettive, Policlinico di Modena, Modena, 6Department of Experimental and Clinical Medicine, University of Florence, 7Policlinico Sant`Orsola-Malpighi, Bologna, Italy, 8Azienda Ospedaliera-Universitaria Senese, Siena, Italy, 9University of Siena, Siena, Italy, 10Clinic of Infectious Diseases, Vita-Salute San Raffaele University, Milano

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OP 84Viral tropism does not have any impact on CD4 recovery in acute HIV infection or AIDS

D. Vita, A. Giacomelli, L. Oreni, P. Tau, G.M. Bottani, V. Micheli, D. Mileto, L. Swenson, C. Brumme, M. Galli, S. Rusconi

Università degli studi di Milano, Milano

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OP 85Antiviral effect of HIV1 tat/rev siRNA carried by nanoparticles in human CD4+ T cell line

F. Falasca1, F. Di Fonzo2, L. Chronopoulou2, I. Sciandra3, C. Palocci2, O. Turriziani1

1Department of Molecular Medicine, 2Department of Chemistry; Sapienza University of Roma, Italy, 3National Institute of Gastroenterology “S. de Bellis”, Research Hospital, Castellana Grotte, Italy

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OP 86A real-life experience of vaccination strategies for HBV prevention in HIV patients

D. Tomasoni, L. Gazzola, D. Barbanotti, A. Tavelli, F. Bai, C. Tincati, S. Cianciola, K. Reister, P. Tognetti, A. De Bona, A. d'Arminio Monforte

Department of Health Sciences, Clinic of Infectious Diseases, ASST Santi Paolo e Carlo, University of Milan, Italy

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OP 87A successful experience of an immunization program in HIV-positive adults

G. Chieffo, L. Maboni, M. Farinazzo, F. Franzetti, B. Menzaghi

ASST Valle Olona Ospedale di Busto Arsizio, Busto Arsizio (VA)

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OP 88Plasma exchange and dolutegravir exposure. A case report

M. Mussa1,2, M. Sciarra1, A. Di Filippo1, R. Maserati3, A. Gaballo4, G. Dornini5, A. Maria Di Matteo3, P. Villani6

1Department of Internal Medicine – University of Pavia, Pavia, Italy, 2Unit of Infectious Diseases, SS Antonio e Biagio e Cesare Arrigo Hospital, Alessandria, Italy, 3Unit of Infectious Diseases, IRCCS San Matteo Hospital Foundation, Pavia, Italy, 4Unit of Nephrology, Dialysis and Transplantation, IRCCS San Matteo Hospital Foundation, Pavia, Italy, 5Immunohaematology and Transfusion Service and Cell Therapy Unit, IRCCS San Matteo Hospital Foundation, Pavia, Italy, 6Laboratory of Pharmacology and Clinical Pharmacokinetics, IRCCS San Matteo Hospital Foundation, Pavia, Italy

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Poster: Bacterial and fungal infections in immunocompromised host

P 1A descriptive analysis of bloodstream infections in patients living with HIV in a large Italian center

A. Ciccullo1, A. Dusina1, B. Fiori2,3, A. Borghetti4, T. D’Inzeo2,3, M. Sanguinetti2,3, F. Pallavicini1,4, T. Spanu2,3, S. Di Giambenedetto1,4

1Section of Infectious Diseases, Department of Safety and Bioethics, Catholic University of the Sacred Heart, Rome, Italy, 2Istituto di Microbiologia, Università Cattolica del Sacro Cuore, Rome, Italy, 3Dipartimento di Scienze di Laboratorio e Infettivologiche, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy, 4UOC Malattie Infettive, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy

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P 2Amebic abscess of the spleen with severe sepsis and bronchial fistulisation in HIV+patient: case report

A. Franco1, F. Acconciagioco2, L. Aprea3, R. Filippelli2, R.M. Franco1, C. Palumbo2, T. Pizzella3, M. Sardo3, F. Simioli3 & E. Manzillo3

1UOSD Profilassi Post-Esposizione - AORN "Ospedali dei Colli" - Napoli, 2UOC Radiodiagnostica P.O. "Cotugno" - AORN "Ospedali dei Colli" - Napoli, 3UOC Immunodeficienze e Malattie dell'Emigrazione - AORN "Ospedali dei Colli" - Napoli

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P 3Pneumocystis jirovecii Pneumonia in HIV-negative Patients, a Frequently Overlooked Problem: Case Series from a Large Italian Center

G. Bozzi1, V. Morena2, A.M. Peri1, L. Taramasso1,3, R. Ungaro1, P. Bono4, A. Grancini4, A. Maraschini4, C. Matinato4, A. Gori1,3, A. Bandera1,3

1Infectious Diseases Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, University of Milan, Milan, Italy, 2III Division of Infectious Diseases, ASST Fatebenefratelli Sacco, Milano, Italy; Department of Biomedical and Clinical Sciences "Luigi Sacco", Università degli Studi di, Milano, Italy, 3Centre for Multidisciplinary Research in Health Science (MACH), Milan, Italy, 4Medical Laboratory of Clinical Chemistry and Microbiology, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy

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P 4Infection by Mycobacterium chimaera in two subjected undergoing cardiac surgery

F. Bulla1, V. Vespertini1, M. de Fazio2, T. Alcaro2, S. Nisticò2, L. Cosco1

1S.O.C. Malattie Infettive A.O. “Pugliese-Ciaccio” Catanzaro, 2S.O.C. Microbiologia A.O. “Pugliese-Ciaccio” Catanzaro

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P 5A case of persistent relapsing abdominal mycobacterial infection requiring prolonged intravenous multi-drug treatment

M. Rossi, A. Soria, L. Bisi, F. Sabbatini, A. Cappelletti, P. Columpsi, S. Foresti, E. Colella, F. Iannuzzi, V. Cogliandro, G. Gustinetti, N. Squillace, P. Vitiello, N. Brianese, E. Pollastri, G. Migliorino, G. Lapadula

Unit of Infectious Diseases, San Gerardo Hospital, ASST Monza

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Poster: Basics in viral hepatitis

P 6Comparison of immunoassays for quantitative serum HBsAg

G. Roncarati, S. Galli, A. Moroni, G. Furlini

Operative Unit of Clinical Microbiology, St. Orsola-Malpighi University Hospital, Bologna

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P 7Cryptic HBV replication is frequently revealed in anti-HBc positive/HBsAg negative patients with HIV infection by applying a highly sensitive digital droplet PCR assay

R. Salpini1, V. Malagnino2, M. Alkhatib1, T. Mulas2, L. Piermatteo1, R. Scutari1, R. Chirichiello1, A. Bertoli1, K. Yu La Rosa1, M. Brugneti1, M. Ciotti3, M. Andreoni2, C.F. Perno4, F. Ceccherini-Silberstein1, L. Sarmati1, V. Svicher1

1Department of Experimental Medicine, Tor Vergata University, Rome, Italy, 2Clinical Infectious Disease, Department of System Medicine, Tor Vergata University, Rome, Italy, 3Microbiology and Virology Unit, Tor Vergata University Hospital, Rome, Italy, 4Department of Oncology and Haemato-oncology, University of Milan, Milan, Italy

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Poster: Cancers in HIV

P 8The multidisciplinary group for HPV related disease and STD in Azienda Ospedaliera Universitaria Pisana (AOUP) Cisanello. An opportunity for HIV and HIV at risk people

L. DelBono1, C. Menconi2, S. Verdenelli1, I. Marchetti3, V. Seccia4, C. Cambi4, P. Cuttano5, S. Panduri6, P. Mazzetti7, F. Maggi7, S. Esim8, A. Gallo9, A.G. Naccarato3, G.Naldini2, M. Pistello7, F. Menichetti1

1UO Malattie Infettive AOU Pisa, 2SOD Chirurgia Proctologica e Perineale AOUP, 3UO Anatomia Patologica 1 AOUP, 4ORL 1 Universitaria AOUP, 5UO Urologia Universitaria AOUP, 6UO Dermatologia Universitaria AOUP, 7Virologia AOUP, 8SOD Microbiologia batteriologica AOUP, 9UOC Igiene e Sanità Pubblica Azienda USL Toscana Nord Ovest

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P 9Non-AIDS-defining cancers in a cohort of HIV positive patients

V. Barocci, S. Mazzanti, M. Di Pietrantonio, A. Polenta, P. Mantini, F. Pallotta, S. Olivieri, B. Candelaresi, L. Brescini, G. De Iaco, A. Fiorentini, O. Cirioni, A. Giacometti

Clinica Malattie Infettive e Tropicali, Parassitologia ed Epatiti croniche, Università Politecnica delle Marche, Ancona

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P 10Case report on oncopathology in HIV-infected patients

Z. Akhmedjanova, D. Urunova, V. Barotova, M. Khasanova, D. Akhmedjanov

Institute of Immunology and Human Genomics, Academy of Sciences of the Republic of Uzbekistan, Tashkent; Tashkent Institute of Advanced Medical Studies, Tashkent;
AIDS Center. Tashkent; University of Toronto, Toronto

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P 11Primitive NHL of bone in an HIV patient: case-report and review of literature

A. Amedeo, D. Testi, G. Ferraro, G. Verucchi , P. Viale , L. Calza

Infectious Disease Section, Alma Mater Studiorum University of Bologna, S.Orsola-Malpighi Hospital, Bologna, Italy

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P 12Alexithymia and cancer-related mortality in Human Immunodeficiency Virus-Infected Patients: An Italian Multisite Prospective Cohort Study

F. Vadini1, F. Sozio1, G. Madeddu3, G. De Socio4, P. Maggi5, B.M. Celesia6, G. Nunnari7, F. Vichi8, P. DiStefano1, E.Tracanna1, E. Polilli2, A. Sciacca1, E. Mazzotta9, B. Zizi3, V. Lai3, C. Bartolozzi8, M.E. Flacco10, P. Bonfanti11, F. Santilli12, L. Manzoli13, G. Parruti1; CISAI Study Group

1Infectious Disease Unit, Pescara, 2Clinical Pathology Laboratory, Pescara, 3Department of Clinical and Experimental Medicine, Unit of Infectious Diseases University of Sassari, Sassari, 4Infectious Diseases Unit, Santa Maria Hospital, Perugia, 5Infectious Diseases Clinic, Policlinico Hospital of Bari, Bari, 6Division of Infectious Diseases, Department of Clinical and Experimental Medicine, ARNAS Garibaldi Hospital Catania, Catania, 7Department of Clinical and Experimental Medicine, University of Messina, Messina, 8Infectious Diseases Unit, Santa Maria Annunziata Hospital, Bagno a Ripoli, Florence, 9Infectious Disease Unit, Teramo, 10Local Health Unit of Pescara, Pescara, 11Infectious Diseases Unit, A. Manzoni Hospital, Lecco, 12Department of Medicine and Aging and Center of Aging Science and Translational Medicine, University of Chieti, Chieti, 13Department of Medical Sciences, University of Ferrara

Abstract
Abstract
Poster
Poster

P 13Kaposi Sarcoma among AIDS-presenters in Modena: could it be a cluster?

E. Bacca1, M. Tutone1, G. Ciusa1, G. Cuomo1, A. Jary2, A.G. Marcelin2, V. Calvez2, V. Borghi1, C. Mussini1

1Clinica di Malattie Infettive e Tropicali, Azienda Ospedaliero Universitaria, Modena, Italy, 2Sorbonne Université, INSERM, Institut Pierre Louis d'Epidémiologie et de Santé Publique (iPLESP), AP-HP, Pitié-Salpêtrière hospital, departement of Virology, Paris, France

Abstract
Abstract
Poster
Poster

P 14Oral Human Papillomavirus (HPV) detection in the context of the multidisciplinary HPV group in Azienda Ospedaliero-Universitaria Pisana (AOUP): a screening opportunity for HIV+ and other at risk-patients

C. Cambi1, S. Verdenelli2, L. Del Bono2, C. Menconi3, P. Mazzetti6, I. Marchetti4, G. Cuttano, E. Balestri6, F. Maggi6, S. Esin8, A. Gallo7, A.G. Naccarato4, G. Naldini3, F. Menichetti2, M. Pistello6, V. Seccia1

1U.O. Otorinolaringoiatria Universitaria AOUP, 2U.O. Malattie Infettive AOUP, 3SOD Chirurgia Proctologica e Perineale AOUP, 4U.O. Anatomia Patologica 1 AOUP, 5U.O. Urologia Universitaria AOUP, 6Virologia AOUP, 7UOC Igiene e Sanità Pubblica Azienda USL Toscana Nord Ovest, 8SOD Microbiologia batteriologica AOUP

Abstract
Abstract
Poster
Poster

P 15HCC Recurrence 8 years post Liver-Transplant was linked to Hepatitis Delta Reactivation in a person living with HIV

G. Ciusa1, G. Dolci1, J. Milic1, M. Tutone1, C. Rogati1, M. Di Gaetano1, E. Franceschini1, N. De Maria2, F. Di Benedetto3, C. Mussini1, G. Guaraldi1

1Clinic of Infectious and Tropical Diseases, University of Modena and Reggio Emilia, Modena, Italy, 2Gastroenterology Unit, Department of Internal Medicine, University of Modena and Reggio Emilia, Modena, Italy, 3Epato-Pancreato-Biliary Surgery and Liver Transplantation Unit, University of Modena and Reggio Emilia, Modena, Italy

Abstract
Abstract
Poster
Poster

P 16Epidemiological analysis from a newly established anal HPV screening ambulatory

M. Ridolfi, E.N. Cavallari, C. Borrazzo, L. Santinelli, G.P. Innocenti, L. Celani, G. De Girolamo, G. Ceccarelli, G. d'Ettorre, C.M. Mastroianni

Dipartimento di Sanità Pubblica e Malattie infettive, Sapienza Università di Roma, Rome

Abstract
Abstract
Poster
Poster

Poster: Cancers in HIV

P 8The multidisciplinary group for HPV related disease and STD in Azienda Ospedaliera Universitaria Pisana (AOUP) Cisanello. An opportunity for HIV and HIV at risk people

L. DelBono1, C. Menconi2, S. Verdenelli1, I. Marchetti3, V. Seccia4, C. Cambi4, P. Cuttano5, S. Panduri6, P. Mazzetti7, F. Maggi7, S. Esim8, A. Gallo9, A.G. Naccarato3, G.Naldini2, M. Pistello7, F. Menichetti1

1UO Malattie Infettive AOU Pisa, 2SOD Chirurgia Proctologica e Perineale AOUP, 3UO Anatomia Patologica 1 AOUP, 4ORL 1 Universitaria AOUP, 5UO Urologia Universitaria AOUP, 6UO Dermatologia Universitaria AOUP, 7Virologia AOUP, 8SOD Microbiologia batteriologica AOUP, 9UOC Igiene e Sanità Pubblica Azienda USL Toscana Nord Ovest

Abstract
Abstract
Poster
Poster
Audio
Audio

P 9Non-AIDS-defining cancers in a cohort of HIV positive patients

V. Barocci, S. Mazzanti, M. Di Pietrantonio, A. Polenta, P. Mantini, F. Pallotta, S. Olivieri, B. Candelaresi, L. Brescini, G. De Iaco, A. Fiorentini, O. Cirioni, A. Giacometti

Clinica Malattie Infettive e Tropicali, Parassitologia ed Epatiti croniche, Università Politecnica delle Marche, Ancona

Abstract
Abstract
Poster
Poster

P 10Case report on oncopathology in HIV-infected patients

Z. Akhmedjanova, D. Urunova, V. Barotova, M. Khasanova, D. Akhmedjanov

Institute of Immunology and Human Genomics, Academy of Sciences of the Republic of Uzbekistan, Tashkent; Tashkent Institute of Advanced Medical Studies, Tashkent;
AIDS Center. Tashkent; University of Toronto, Toronto

Abstract
Abstract
Poster
Poster

P 11Primitive NHL of bone in an HIV patient: case-report and review of literature

A. Amedeo, D. Testi, G. Ferraro, G. Verucchi , P. Viale , L. Calza

Infectious Disease Section, Alma Mater Studiorum University of Bologna, S.Orsola-Malpighi Hospital, Bologna, Italy

Abstract
Abstract
Poster
Poster
Audio
Audio

P 12Alexithymia and cancer-related mortality in Human Immunodeficiency Virus-Infected Patients: An Italian Multisite Prospective Cohort Study

F. Vadini1, F. Sozio1, G. Madeddu3, G. De Socio4, P. Maggi5, B.M. Celesia6, G. Nunnari7, F. Vichi8, P. DiStefano1, E.Tracanna1, E. Polilli2, A. Sciacca1, E. Mazzotta9, B. Zizi3, V. Lai3, C. Bartolozzi8, M.E. Flacco10, P. Bonfanti11, F. Santilli12, L. Manzoli13, G. Parruti1; CISAI Study Group

1Infectious Disease Unit, Pescara, 2Clinical Pathology Laboratory, Pescara, 3Department of Clinical and Experimental Medicine, Unit of Infectious Diseases University of Sassari, Sassari, 4Infectious Diseases Unit, Santa Maria Hospital, Perugia, 5Infectious Diseases Clinic, Policlinico Hospital of Bari, Bari, 6Division of Infectious Diseases, Department of Clinical and Experimental Medicine, ARNAS Garibaldi Hospital Catania, Catania, 7Department of Clinical and Experimental Medicine, University of Messina, Messina, 8Infectious Diseases Unit, Santa Maria Annunziata Hospital, Bagno a Ripoli, Florence, 9Infectious Disease Unit, Teramo, 10Local Health Unit of Pescara, Pescara, 11Infectious Diseases Unit, A. Manzoni Hospital, Lecco, 12Department of Medicine and Aging and Center of Aging Science and Translational Medicine, University of Chieti, Chieti, 13Department of Medical Sciences, University of Ferrara

Abstract
Abstract
Poster
Poster

P 13Kaposi Sarcoma among AIDS-presenters in Modena: could it be a cluster?

E. Bacca1, M. Tutone1, G. Ciusa1, G. Cuomo1, A. Jary2, A.G. Marcelin2, V. Calvez2, V. Borghi1, C. Mussini1

1Clinica di Malattie Infettive e Tropicali, Azienda Ospedaliero Universitaria, Modena, Italy, 2Sorbonne Université, INSERM, Institut Pierre Louis d'Epidémiologie et de Santé Publique (iPLESP), AP-HP, Pitié-Salpêtrière hospital, departement of Virology, Paris, France

Abstract
Abstract
Poster
Poster

P 14Oral Human Papillomavirus (HPV) detection in the context of the multidisciplinary HPV group in Azienda Ospedaliero-Universitaria Pisana (AOUP): a screening opportunity for HIV+ and other at risk-patients

C. Cambi1, S. Verdenelli2, L. Del Bono2, C. Menconi3, P. Mazzetti6, I. Marchetti4, G. Cuttano, E. Balestri6, F. Maggi6, S. Esin8, A. Gallo7, A.G. Naccarato4, G. Naldini3, F. Menichetti2, M. Pistello6, V. Seccia1

1U.O. Otorinolaringoiatria Universitaria AOUP, 2U.O. Malattie Infettive AOUP, 3SOD Chirurgia Proctologica e Perineale AOUP, 4U.O. Anatomia Patologica 1 AOUP, 5U.O. Urologia Universitaria AOUP, 6Virologia AOUP, 7UOC Igiene e Sanità Pubblica Azienda USL Toscana Nord Ovest, 8SOD Microbiologia batteriologica AOUP

Abstract
Abstract
Poster
Poster

P 15HCC Recurrence 8 years post Liver-Transplant was linked to Hepatitis Delta Reactivation in a person living with HIV

G. Ciusa1, G. Dolci1, J. Milic1, M. Tutone1, C. Rogati1, M. Di Gaetano1, E. Franceschini1, N. De Maria2, F. Di Benedetto3, C. Mussini1, G. Guaraldi1

1Clinic of Infectious and Tropical Diseases, University of Modena and Reggio Emilia, Modena, Italy, 2Gastroenterology Unit, Department of Internal Medicine, University of Modena and Reggio Emilia, Modena, Italy, 3Epato-Pancreato-Biliary Surgery and Liver Transplantation Unit, University of Modena and Reggio Emilia, Modena, Italy

Abstract
Abstract
Poster
Poster

P 16Epidemiological analysis from a newly established anal HPV screening ambulatory

M. Ridolfi, E.N. Cavallari, C. Borrazzo, L. Santinelli, G.P. Innocenti, L. Celani, G. De Girolamo, G. Ceccarelli, G. d'Ettorre, C.M. Mastroianni

Dipartimento di Sanità Pubblica e Malattie infettive, Sapienza Università di Roma, Rome

Abstract
Abstract
Poster
Poster

Poster: Gender issues

P 17Behavioural and awareness changes in a HIV prevention program based on women empowerment in Uganda

G. Micheli2, C. Seguiti2, F.V. Segala2, A. Pierantozzi3, F. Opira4, S. Di Murro2, A. D’Angelillo2, T. Tabu4, M. Chiuchiarelli2, D. Faliero2, B. Odong6, R. Lukwiya4, F.S. Aloi5, K. De Gaetano Donati1, A. Cingolani1,2 for 'Pe Atye Kena, no longer alone' study group

1Fondazione Policlinico A. Gemelli, IRCCS, Istituto di Clinica delle Malattie Infettive, Roma, 2Università Cattolica S. Cuore, Malattie Infettive, Roma, 3AIFA-Agenzia Italiana del farmaco, Roma, 4"Comboni Samaritans of Gulu” Health Center, Gulu, Uganda, 5Università Cattolica S. Cuore, Patologia Speciale Medica e Semeiotica Medica, Roma, 6Medical Teams International, Kitgum, Uganda

Abstract
Abstract
Poster
Poster

P 18Therapy burdens of Italian women living with HIV - Findings from the Positive Perspectives 2 Study

G.M. Corbelli1, S. Marcotullio2, P. Rizzini2, P. de los Rios3, A. Appiah4

1Plus Onlus, Bologna, Italy, 2ViiV Healthcare Verona VR, Italy, 3ViiV Healthcare Laval, Quebec, Canada, 4ViiV Healthcare Brentford, UK

Abstract
Abstract
Poster
Poster
Audio
Audio

P 19Transgender people and HIV

M. Formisano1, M. Errico2, A. Giacomelli3, D. Bernacchia4, G. Casella5, A. Tosano6, L. Brogonzoli7

1NPS Italia Onlus Vice President, Milan, 2NPS Italia Onlus President, Milan, 3III Infectious Diseases Unit, ASST-FBF-Sacco, Department of Biomedical and Clinical Sciences DIBIC Luigi Sacco, University of Milan, member of SIMIT, Milan, 4III Infectious Diseases Unit, ASST-FBF-Sacco, Department of Biomedical and Clinical Sciences DIBIC Luigi Sacco, University of Milan, member of SIMIT, Milan, 5NPS Italia Onlus Junior Researcher, Milan, 6NPS Italia Onlus Senior Researcher, Milan, 7NPS Italia Onlus Head Researcher, Milan

Abstract
Abstract
Poster
Poster

P 20HIV-positive transgender people in follow-up at an Italian single tertiary care hospital in Florence: a cross-sectional study

F. Lagi1, A. Botta1, S.T. Kiros1, M. Mazzetti2, A. Bartoloni1,2, G. Sterrantino1

1Department of Experimental and Clinical Medicine, University of Florence, Florence Italy, 2Infectious and Tropical Diseases Unit, Careggi University and Hospital, Florence, Italy

Abstract
Abstract
Poster
Poster

P 21HPV and bacterial vaginal infection impact on immune system in a cohort of HIV female population under suppressive ART

A. Carraro1, P. Nijhawan1, S. Vita2, R. Marocco2, L. Fondaco1, B. Kertusha1, L. Ansaldo1, V. Petrozza1,3, J. Cacciotti3, M. Renzelli2, C.M. Mastroianni1, M. Lichtner1,2

1Dept. Of Public health and Infection Disease, Sapienza, University of Rome, Italy, 2Infectious Disease Unit, SM Goretti Hospital, Latina, 3Pathological Anatomy, ICOT, Sapienza, University of Rome, Italy

Abstract
Abstract
Poster
Poster

Poster: HCV elimination

P 22Qualitative analysis of significant clinical events in a cohort of patients after DAA treatment for chronic HCV infection after virological eradication

M. Mazzitelli, C. Costa, V. Pisani, G. Greco ,F. Serapide, V. Scaglione, R. Lionello, V. La Gamba, E.M. Trecarichi, C. Torti

Infectious and Tropical Disease Unit, “Magna Graecia University”, Catanzaro, Italy

Abstract
Abstract
Poster
Poster

P 23A fast track city micro-project to eradicate HCV infection in PLWHIV

F. Maggiolo, L. Comi, E. Di Filippo, R. Teocchi, D. Valenti, A. Callegaro, M. Rizzi

ASST Papa Giovanni XXIII, Bergamo

Abstract
Abstract
Poster
Poster
Audio
Audio

P 24A pilot intervention for HCV elimination among MSM in Rome: preliminary results

P. Piselli1, M. Giuliani2, M. Farinella3, C. Cimaglia1, A. Latini2, F. Carduccelli3, C. Ancona2, O. Bruzzi1, G. De Carli1, R. Esvan1, F. Gili1, M. Marra3, N. Orchi1, E. Piscitelli1, S. Pittalis1, A.R. Garbuglia1, A. Amendola1, S. Meschi1, S. Cicalini1, M. De Palo1, E. Grilli1, A. Antinori1, M.R. Capobianchi1, A. Cristaudo2, G. D’Offizi1, V. Puro1, E. Girardi1

1INMI “L. Spallanzani” IRCCS, Rome, 2Istituto Dermatologico San Gallicano, IRCCS, Rome, 3Circolo di Cultura Omosessuale “Mario Mieli”, Rome, Italy

Abstract
Abstract
Poster
Poster

P 25HCV eradication in people living with HIV in Sassari: the final countdown?

A. De Vito, N. Geremia, S. Malnati, V. Fiore, E. Princic, A.A. Muredda, M.A. Seazzu, I. Maida, S. Babudieri, G. Madeddu

Unit of Infectious Diseases, Department of Medical, Surgical and Experimental Sciences, University of Sassari, Sassari, Italy

Abstract
Abstract
Poster
Poster

P 26Glecaprevir/Pibrentasvir and Sofosbuvir/Velpatasvir/Voxilaprevir failure in a young man with genotype 1a congenital HCV infection: a case presentation

P. Columpsi*1, A.Soria1, E. Colella1, N. Squillace1, P. Vitiello1, M. Rossi1, G. Migliorino1, S. Paolucci2, F. Baldanti2,3, G. Lapadula1

1Unit of Infectious Diseases, San Gerardo Hospital, ASST Monza, 2Molecular Virology Unit, Microbiology and Virology Department, Fondazione Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Policlinico, San Matteo, Pavia, Italy, 3Department of Clinical, Surgical, Diagnostic and Pediatric Sciences, University of Pavia, Pavia, Italy

Abstract
Abstract
Poster
Poster

P 27Acute hepatitis C treatment with direct antiviral agents (DAAs) in patients with solid organ cancer

V. Bianco1, C. Dell'Isola1, F. Martucci1, B. Matteis1, G. Morelli1, P. Pierri1, R. Punzi2

1Infectious Disease Specialist, "D. Cotugno" hospital, Naples, Italy, 2Head of Infectious Disease, "D. Cotugno" hospital, Naples, Italy

Abstract
Abstract
Poster
Poster

P 28How to eliminate HCV in people who inject drugs? Preliminary results of a provincial multi-targeted approach involving three different settings: addictions services, prison, outreach mobile unit for active users

A. Soria1, E. Colella1, P. Columpsi1, E. Chiesa2, A. Cardia3, M. Bramani Araldi4, D. Leto3, G. Scaffidi4, S. Mancastroppa2, C. De Ferrari3, A. Caruso4, S. Marangon2, M. Pecoraro5, B. Tinghino5, G. Galimberti2, L. Vaira6, M. Grilli7, A. Cocchini7, C. Bregamo8, R. Galizzi8, G. Marconi9, G. Migliorino1, G. Lapadula1

1Unit of Infectious Diseases, San Gerardo Hospital, ASST Monza, 2Addiction service (SERD) of Monza, ASST Monza, 3Addiction service (SERD) of Limbiate, ASST Monza, 4Addiction service (SERD) of Carate Brianza, ASST Vimercate, 5Service of Alcohol disorders and new addictions (NOA) of Seregno, ASST Vimercate, 6Presidio Sanitario Penitenziario, ASST Monza, 7SERD Casa Circondariale Monza, 8Cooperativa Lotta Contro L’Emarginazione, 9UOS Raccordo della Rete Territoriale dei Servizi, ATS Brianza

Abstract
Abstract
Poster
Poster
Audio
Audio

P 29Innovative procedures for micro-elimination of HCV infection in persons who use drug (PWUD)

M. Pisaturo2,4, V. Messina1, A. Russo1,2, E. Parente3, G. Russo3, T. Raimondo3, A. Salzillo1, F. Simeone1, L. Onorato1, G. Di Caprio1, N. Coppola1,2,

1Infectious Diseases Unit, AORN Sant’Anna e San Sebastiano, Caserta, Italy; 2Department of Mental Health and Public Medicine, Section of Infectious Diseases, Second University of Naples, Italy, 3SerD Teano, Piedimonte Matese (Caserta); Italy, 4AORN Dei Colli, Ospedale Cotugno, Naples

Abstract
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Poster
Poster

P 30Short course therapy for chronic hepatitis C infection

G. Stroffolini, T. Lupia, G. Cariti, L. Boglione , G. Di Perri

Amedeo di Savoia Hospital, University of Torino, department of medical science

Abstract
Abstract
Poster
Poster

P 31DAA failure in HCV genotype 3: virological features and efficacy of re-treatment

M. Pisaturo1,4, L. Occhiello1, M. Starace1, C. Minichini1, A. Di Fraia1, S. De Pascalis2, M. Macera2, V. Messina3, V. Sangiovanni4, E. Claar5, D. Precone6, G. Stornaiuolo2, M.Stanzione2, I. Gentile8, G. Brancaccio2, S. Martini9, A. Masiello10, A. Salomone Megna11, C. Coppola12, A. Federico13, E. Sagnelli1, M. Persico14, A. Galeota Lanza15, A.Marrone16, G.B. Gaeta2, N. Coppola1,3

1Laboratory for the identification of prognostic factors of response to the treatment against infectious diseases, University of Campania "L. Vanvitelli", Napoli, Italy, 2Infectious Diseases and Viral Hepatitis, Department of Mental and Physical Health and Preventive Medicine, University of Campania "L. Vanvitelli", Napoli, Italy, 3Infectious Diseases Unit, A.O. S Anna e S Sebastiano Caserta, Italy, 4Third Infectious Diseases Unit, AORN deiColli, P.O. Cotugno, Naples, Italy, 5Internal Medicine Unit, Evangelical Hospital Villa Betania Naples, Italy, 6Internal Medicine Unit A.O Sarno, Sarno (SA) Campania L. Vanvitelli, &Infectious and Transplant Medicine, AORN Ospedali dei Colli- Monaldi Hospital, Naples, Italy, 7Gastroenterology Unit, AOU San Giovanni di Dio Ruggi d'Aragona, Salerno Italy, 8Infectious Diseases Unit, University Federico II, Naples, Italy, 9HIV Unit, University of Campania L.Vanvitelli, Naples, Italy, 10Infectious Diseases Unit, A.O S.G. Moscati, Avellino Italy, 11Infectious Diseases Unit, A. OG.Rummo, Benevento, 12Hepatology Unit, Gragnano Hospital, Gragnano, 13Internal Medicine and Hepatology Department of Clinical and Experimental Medicine, University of Campania "L. Vanvitelli", 14Internal Medicine and Hepatology Unit, PO G. Da Procida-AOU- San Giovanni e Ruggi D'Aragona,University of Salerno, 15Hepatology Unit,Cardarelli Hospital, Naples, Italy, 16Department of Medical, Surgical, Neurological, Metabolic, and Geriatric Sciences, University of Campania "L. Vanvitelli"

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Poster

P 32Therapy of Hepatitis C in Prison: Experience of Systematic Treatment Program in Rome

S. Rosati1, S. Lardo1, S. Marcellini2, G. Iannicelli1, P. Magrini3, C. Leonardi4, M. Zaccarelli1

1INMI L. Spallanzani, Rome (Italy), 2Infectivologist Doctor for Rebibbia Prison, 3Health Director ASL Frosinone, 4Health Director ASL RM 2 for Drug Addictions and Prisons

Abstract
Abstract
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Poster
Audio
Audio

P 33Five years real-life experience with direct-acting antivirals for hepatitis C in a suburban setting in Rome: a retrospective analysis

L. Foroghi Biland, E. Teti, G. De Simone, T. Mulas, L. Campogiani, C. Stingone, L. Ferrari, M. De Masi, L. Coppola, M. Compagno, M. Iannetta, L. Sarmati, M. Andreoni

Infectious Diseases Clinic, Tor Vergata University Hospital, Rome, Italy

Abstract
Abstract
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Poster

P 34Association Between Polymorphism in the Enhancer Gene and Hepatitis C Virus-induced Hepatocellular Cancer Risk

G. Greco1, V. Folliero2, V. Valastro1, D. D’orio1, F. Pinto1, S.A. Maiella1, M.V. Morone1, G. Franci3, L. Rinaldi4, M. Galdiero1

1Department of Experimental. Medicine, Section of Virology and Microbiology University of Campania “Luigi Vanvitelli”, Naples, Italy, 2Section of Microbiology and Virology, University Hospital Luigi Vanvitelli of Naples, Naples, Italy, 3Department of medicine, Surgery and Dentistry “Scuola Medica Salernitana”, University of Salerno, Baronissi (SA), Italy, 4Department of Advanced Medical and Surgical Sciences, University of Campania "Luigi Vanvitelli", Naples, Italy

Abstract
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Poster
Audio
Audio

P 35Genotyping and treatment issues with unusual 1e and 1g HCV subtypes from African subjects: report of two cases

C. Caudai1, P. Pierotti2, P. Galluzzi3, B. Rossetti3, P. Blanc2, M. Zazzi4

1Microbiology and Virology Unit, Siena University Hospital , Siena, Italy, 2Infectious Diseases Unit, S. Maria Annunziata Hospital, Florence , Italy, 3Infectious Diseases Unit, Siena University Hospital , Siena, Italy, 4Department of Medical Biotechnologies, University of Siena, Siena, Italy

Abstract
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Poster

P 36Feasibility and impact of HCV treatment in a HRS in Milan

G. Cocca1, V. Casigliani2, T. Sebastiani1, S. Mazzilli2,3, D. Bugatti1, G. Visi2, A. Stemat4, G. Arzilli2, P. Vigezzi1, C. Nicola1, P. Selva1, C. Catani1, L. Tavoschi2, R. Ranieri4

1Local Harm Reduction Service, San Paolo University Hospital, Milan, Italy Department of 2Translational Research and New Technologies in Medicine and Surgery, University of Pisa, Italy, 3Scuola Normale Superiore, Pisa, 4Penitentiary Infectious Diseases Unit, San Paolo University Hospital, Milan, Italy

Abstract
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Audio
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P 37An effective strategy to achieve HCV micro-elimination: HCV test and treatment into two Harm Reduction Services in Milan

T. Sebastiani1, S. Mazzilli2,3, G. Cocca1, V. Casigliani2, A. Stemat4, G. Arzilli2, P. Vigezzi1, G. Visi2, D. Bugatti1, C. Nicola1, P. Selva1, C. Catani1, L. Tavoschi2, R. Ranieri4

1Local Harm Reduction Servece, San Paolo University Hospital, Milan, Italy Department of, 2Translational Research and New Technologies in Medicine and Surgery, University of Pisa, Italy, 3Scuola Normale Superiore, Pisa, 4Penitentiary Infectious Diseases Unit, San Paolo University Hospital, Milan, Italy

Abstract
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P 38Long follow up of monocyte-macrophage immuneactivation markers in HCV mono-infected patients undergoing DAA treatment

B. Kertusha1, P. Nijhawan1, L. Fondaco1, A. Curtolo1, C. Mascia1, I. Pozzetto1, R. Marocco2, A. Carraro1, F. Cogliati Dezza1, V. Rossi2, T. Tieghi2 , S. Vita2, C. Mastroianni1, M. Lichtner1,2

1Department of Public health and Infectious disease, Sapienza, University of Rome, 2Infectious Disease Unit, SM Goretti Hospital Latina

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P 39EradichiamoCi: HCV micro-eradication project among 5 psychoactive substances user services using a DAA delivery strategy

P. Zuccala’1, R. Marocco1, G. Di Palma2, B. Kertusha2, L. Fondaco2, M. D’Achille1, V. Rossi1, A. Mecozzi3, T. Franci3, C. De Mei4, E. Mattacchioni4, W. Kebebe4, G. Papa4, G.Padula5, T. Danieli5, O. Coletta6, A. Parente6, F. Aiuti7, E. Montanari7, P. Spina8, C. Paiano8, A. Vetica1, M.P. Giardino5, M. Lichtner1,2

1UOC Infectious Disease, Ospedale S.Maria Goretti, Latina, 2Sapienza University of Rome, Polo Pontino, Latina, 3Hospital Farmacy, Ospedale S.Maria Goretti, Latina, 4Ser.D Latina, ASL Latina, Latina, 5Ser.D Terracina, ASL Latina, Terracina, 6Ser.D Formia, ASL Latina, Formia, 7Ser.D Priverno, ASL Latina, Priverno, 8Ser.D Aprilia, ASL Latina, Aprilia

Abstract
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Poster

P 40Effect of direct antiviral therapy against HCV on CD4+ T cell count in patients with HIV-HCV coinfection

B. Pinchera, A.R. Buonomo, R. Scotto, E. Zappulo, F. Borrelli, M.R. Cotugno, G. Di Filippo, I. Gentile

Department of Clinical Medicine and Surgery, University of Naples "Federico II", Naples, Italy

Abstract
Abstract
Poster
Poster

P 41HCV treatment in PWID: a linkage to care model in Cagliari

F. Pes1, C. Balestrieri1, M. Casale2, M. Buffa1, C. Guiso3, R. Altea4, O. Angioni5, L. Barca1, A. Cola2, S. Onali1, L. Chessa1,2

1Department of Medical Sciences and Public Health; Monserrato (CA) Italy, 2Liver Unit, University Hospital, Monserrato (CA) Italy, 3Ser.D. via Liguria, ATS, Cagliari, Italy , 4Ser.D. Via dei Valenziani, ATS, Cagliari, Italy, 5Ser.D., Quartu S.E. (CA), ATS, Italy

Abstract
Abstract
Poster
Poster

Poster: Hepatitis epidemiology

P 42Hepatitis A: has the outbreak ended?

E. Garlatti Costa1, P. Martelli2, R. Giacomello2, A. Berto3, A. Grembiale1, S. Grazioli1, R. De Rosa3, D. Villalta2, M. Tonizzo1

1Department of Internal Medicine, ASFO, Pordenone, 2Department of Immunology and Allergology, ASFO, Pordenone, 3Department of Microbiology and Virology, ASFO, Pordenone

Abstract
Abstract
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Poster

P 43Re-treatment of HCV infection following failure to DAAs: data from the SCOLTA cohort

L.A. Nicolini1, B. Menzaghi2, P. Bonfanti3, F. Vichi4, A. Cascio5, A. Parisini6, G. V. De Socio7, K. Falasca8, A. Di Biagio1,9

1Infectious Diseases, Policlinico San Martino-IRCCS, Genova, Italy, 2Unit of Infectious Diseases, ASST della Valle Olona, Busto Arsizio Hospital, Busto Arsizio, Italy, 3Infectious Disease Unit, Ospedale A. Manzoni, Lecco, Italy, 4Infectious Diseases Unit, Santa Maria Annunziata Hospital, Bagno a Ripoli, Florence, Italy, 5Department of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties, University of Palermo, Palermo, Italy, 6Infectious Diseases Unit, SS. Antonio e Biagio e Cesare Arrigo Hospital, Alessandria, Italy, 7Unit of Infectious Diseases, Department of Medicine 2, Azienda Ospedaliera di Perugia, Santa Maria Hospital, Perugia, 8Clinic of Infectious Diseases, Department of Medicine and Science of Aging, University 'G. d'Annunzio' Chieti-Pescara, Chieti, Italy, 9Department of Health Sciences (DISSAL), University of Genoa, Genova, Italy

Abstract
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Poster

P 44HEV in Southern Italy. Still a chimera?

C. Dell'Isola, B.M. Matteis, F. Martucci, G. Morelli, P. Pierri, V. Bianco, R. Punzi

Division of hepatic diseases- AORN "dei Colli" Monaldi-Cotugno-CTO, Naples

Abstract
Abstract
Poster
Poster

P 45Evaluation of early HCC occurrence rate and its risk factors in HCV patients treated with direct-acting antivirals

V. Valastro1, F. Foglia1, G. Greco1, D. D’orio1, F. Pinto1, S.A. Maiella1, M.V. Morone1, G. Franci2, M. Galdiero1

1Department of Experimental. Medicine, Section of Virology and Microbiology University of Campania “Luigi Vanvitelli”, Naples, Italy, 2Department of Medicine, Surgery and Dentistry “Scuola Medica Salernitana”, University of Salerno, Baronissi (SA), Italy

Abstract
Abstract
Poster
Poster
Audio
Audio

Poster: HIV and COVID

P 46Covid-19 in patients with HIV-1 infection: a single-centre experience in Northern Italy

L. Calza1, I. Bon2, V. Colangeli1, M. Borderi1, G. Beci1, F. Esposito1, L. Badia1, M. Tadolini1, M.C. Re2, P. Viale1

1Unit of Infectious Diseases and 2Unit of Microbiology, S.Orsola Hospital, University of Bologna, Bologna (Italy)

Abstract
Abstract
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Poster

P 47A case of acute hepatitis C in a patient with HIV, occult HBV and SARS-CoV-2 co-infection

E. Garlatti Costa1, A. Grembiale1, C. Mazzaro2, A. Rosso1, A. Berto3, S. Grazioli1, O. Schioppa4, R. De Rosa3, M. Tonizzo1

1Department of Internal Medicine, Azienda Sanitaria Friuli Occidentale (ASFO), Pordenone, Italy, 2Department of Experimental Onco-Hematology, Centro Riferimento Oncologico (CRO), IRCCS, Aviano, Italy, 3Department of Microbiology and Virology, Azienda Sanitaria Friuli Occidentale (ASFO), Pordenone, Italy, 4Department of Oncology, Centro Riferimento Oncologico (CRO), IRCCS, Aviano, Italy

Abstract
Abstract
Poster
Poster

P 48SARS-CoV-2 infection in a highly-experienced person living with HIV

A. Ciccullo1,2, P. Del Giacomo1, A. Porfidia3, G. De Matteis3, R. Cianci3, F. De Vito3, A. Dusina1,2, A. Borghetti1, M. Tumbarello1,2, S. Di Giambenedetto1,2

1Fondazione Policlinico Universitario Agostino Gemelli IRCCS, UOC Malattie Infettive, Rome, Italy, 2Section of Infectious Diseases, Department of Safety and Bioethics, Catholic University of the Sacred Heart, Rome, Italy, 3Fondazione Policlinico Universitario Agostino Gemelli IRCCS, UOC Medicina Generale, Rome, Italy

Abstract
Abstract
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Poster

P 49SARS-CoV-2 infection in a HIV+ patient on darunavir-based ART monotherapy: a case report

G.E. Recchia1, M. Ridolfi1, G. Siccardi1, F. Cogliati Dezza1, F. Alessi1, C. Pinacchio1, L. Santinelli1, G.P. Innocenti1, C. Scagnolari2, G. Ceccarelli1, G. d'Ettorre1, C. Mastroianni1

1Department of Public Health and Infectious Diseases, Sapienza University of Rome, Rome, Italy, 2Laboratory of Virology, Department of Molecular Medicine, affiliated to Istituto Pasteur Italia - Cenci Bolognetti Foundation, Sapienza University, Rome, Italy

Abstract
Abstract
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Poster

P 50COVID-19 in people living with HIV (PLWH): clinical picture, viral clearance, cellular and antibody response in a case series of a reference HIV/AIDS center in a COVID Hospital in Rome

A. Mondi1, E. Cimini2, F. Colavita3, S. Cicalini1, C. Pinnetti1, G. Matusali3, R. Casetti2, A. Vergori1, V. Mazzotta1, R. Gagliardini1, V. Schininà4, E. Girardi5, V. Puro6, G Ippolito7, M. Capobianchi3, C. Castilletti3, C. Agrati2, A. Antinori1

1HIV/AIDS Department, National Institute for Infectious Diseases, Lazzaro Spallanzani IRCCS, Rome, Italy, 2Cellular Immunology and Pharmacology Laboratory, National Institute for Infectious Diseases, Lazzaro Spallanzani IRCCS, Rome, Italy, 3Laboratory of Virology, National Institute for Infectious Diseases, Lazzaro Spallanzani IRCCS, Rome, Italy, 4Radiology Unit, National Institute for Infectious Diseases Lazzaro Spallanzani IRCCS, Rome, Italy, 5Clinical Epidemiology Unit, National Institute for Infectious Diseases Lazzaro Spallanzani, IRCCS, Rome, Italy, 6AIDS Reference Center - National Institute for Infectious Diseases Lazzaro Spallanzani IRCCS, Rome, Italy, 7Scientific Direction, National Institute for Infectious Diseases Lazzaro Spallanzani, IRCCS, Rome, Italy

Abstract
Abstract
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Poster
Audio
Audio

P 51Clinical course and viroimmunological impact of COVID-19 in HIV infected patients: a single-center report from Milan, Italy

A. Mastrangelo1, C. Muccini1, E. Bruzzesi1, M. Ranzenigo1, M. Chiurlo1, L. Galli2, A. Poli2, A. Castagna1,2, A. Lazzarin2, P. Cinque2
on behalf of the HIV-COVID OSR Study Group2 (E. Messina, A. Danise, M. Guffanti, R. dell’Acqua, S. Nozza, N. Gianotti, V. Spagnuolo, L. Fumagalli, H. Hamid, S. Bossolasco, G. Morsica, G. Gaiera, M. Cernuschi, M. Ripa, B. Castiglioni, C. Oltolini, D. Canetti, C. Tassan-Din, A. Andolina, P. Scarpellini, G. Tambussi, C. Uberti-Foppa)

1Vita-Salute San Raffaele University, Milan, 2Unit of Infectious Diseases, San Raffaele Hospital, Milan

Abstract
Abstract
Poster
Poster

P 52Management of emergency COVID-19 in prison, Monza experience

L.M. Vaira1, V. Costa1, M. Pitaniello2

1Medical Prison Unit, San Gerardo Hospital, ASST-Monza, Monza, Italy, 2Prison director of Monza

Abstract
Abstract
Poster
Poster

P 53Psychological impact and awareness of COVID-19 in young people with HIV

S. Bernardi1, E. Mozzo2, M. Di Pastena1, F. Leone3, C. Novello2, A. Oletto2, N. Cotugno4, P. Zangari4, P. Palma4, V. Santilli4, P. Palma4, O. Rampon5, C. Giaquinto2

1DPUO Immunoinfettivologia, Ospedale Pediatrico Bambino Gesù, Roma, 2Fondazione Penta, Padova, 3Università degli Studi di Roma, 4UOC Immunologia Clinica – DPUO, Ospedale Pediatrico Bambino Gesù, Roma, 5Department of Women's and Children's Health, University of Padova

Abstract
Abstract
Poster
Poster
Audio
Audio

P 54Review of lopinavir and darunavir use in SARS-CoV-2 and HIV co-infection: is it time to find another role and another actor?

E. Garlatti Costa1, R. Ranieri2, G. Basaglia3, R. De Rosa3, M. Tonizzo1

1Department of Internal Medicine, Azienda Sanitaria Friuli Occidentale, Pordenone, Italy, 2Infectious Diseases Service, Penitentiary Health System, San Paolo University Hospital, Milano, Italy, 3Department of Microbiology and Virology, Azienda Sanitaria Friuli Occidentale, Pordenone, Italy

Abstract
Abstract
Poster
Poster

P 55Seroprevalence of SARS-CoV2 antibodies in paediatric HIV patients

S. Bernardi, C. Casamento Tumeo, C. Concato, L. Coltella, S. Ranno, G. Linardos, L. Piccioni, C.F. Perno

Bambino Gesu' Children's Hospital Rome Italy

Abstract
Abstract
Poster
Poster

Poster: HIV and nervous system

P 56Study of the types of the nervous system based on temperaments of HIV-infected patients

Z. Akhmedjanova1, D. Urunova2, Z. Kadyrova3

1Institute of Human Immunology and Genomics, Tashkent, 2Academy of Sciences of the Republic of Uzbekistan, Tashkent, 3Tashkent Institute for Advanced Medical Studies, Tashkent

Abstract
Abstract
Poster
Poster

P 57Persistent activation of CXCL13 axis in the Cerebrospinal fluid of People Living with HIV despite Central Nervous System Viral Suppression

M. Trunfio1, L. Mighetto2, S. Torresan1, C. Atzori3, S. Biffi1, M. Nigra2, D. Imperiale3, S. Bonora1, G. Di Perri1, A. Calcagno1

1Infectious Diseases unit, Amedeo di Savoia hospital, University of Torino, Torino, Italy, 2Diagnostic Laboratory unit, Maria Vittoria hospital, ASL Città di Torino, Torino, Italy, 3Neurology unit, Maria Vittoria hospital, ASL Città di Torino, Torino, Italy

Abstract
Abstract
Poster
Poster

P 58Limited health literacy (HL) ability and low awareness of HL difficulties in people living with HIV

V. Delle Donne1, N. Ciccarelli2, V. Massaroni, F. Lombardi1, C. Picarelli1, A. Borghetti, A. Emiliozzi1, A. Dusina1, A. Ciccullo1, D. Moschese1, G. Baldin1,5, D. Farinacci1, S. Di Giambenedetto1,4, M. Fabbiani3

1Università Cattolica del Sacro Cuore, Roma Italia, Istituto di Clinica Malattie Infettive, 2Dipartimento di Psicologia, Università Cattolica di Milano, 3UOC Malattie Infettive e Tropicali, Azienda Ospedaliero-Universitaria Senese, Siena, Italy, 4Fondazione Policlinico Universitario A. Gemelli IRCCS, Roma Italia, UOC malattie infettive, 5Mater Olbia Hospital, Olbia, Italy

Abstract
Abstract
Poster
Poster
Audio
Audio

P 59Evolution of cognitive performance at a 2 years follow-up in a group of HIV-infected patients

V. Delle Donne1, N. Ciccarelli2, V. Massaroni1, F. Lombardi1, C. Picarelli1, A. Borghetti1, A. Emiliozzi1, A. Dusina1, A. Ciccullo1, D. Moschese1, G. Baldin1,5, D. Farinacci1, S. Di Giambenedetto1,4, M. Fabbiani3

1Università Cattolica del Sacro Cuore, Roma Italia, Istituto di Clinica Malattie Infettive, 2Dipartimento di Psicologia, Università Cattolica di Milano, 3UOC Malattie Infettive e Tropicali, Azienda Ospedaliero-Universitaria Senese, Siena, Italy, 4Fondazione Policlinico Universitario A. Gemelli IRCCS, Roma Italia, UOC malattie infettive, 5Mater Olbia Hospital, Olbia, Italy

Abstract
Abstract
Poster
Poster
Audio
Audio

P 60Cerebrospinal fluid viral replication and burden of resistance in HIV-1-infected people with multidrug resistance treated with Ibalizumab

C. Muccini1, D. Canetti2, A. Bigoloni2, V. Spagnuolo1,2, L. Galli2, A. Poli2, M. Cernuschi2, P. Cinque2, E. Boeri3, M. Sampaolo3, A. Lazzarin2, A. Castagna1,2

1Vita-Salute San Raffaele University, Milan, Italy, 2Infectious Diseases, IRCCS San Raffaele Scientific Institute, Milan, Italy, 3Laboratory of Microbiology and Virology, IRCCS San Raffaele, Milan, Italy

Abstract
Abstract
Poster
Poster
Audio
Audio

P 61In Vitro Effect of Efavirenz on Cultured Primary Astrocytes: Analysis of Neurotoxicity and Matrix Metalloproteinase Inhibition

I. Pati1, T. Latronico1, S. Milella1, A. Fasano1, F. Mengoni2, M. Lichtner3, C.M. Mastroianni2, G.M. Liuzzi1

1Department of Biosciences, Biotechnology and Biopharmaceutics, University of Bari "A. Moro", Bari, Italy, 2Department of Public Health and Infectious Diseases, Sapienza University, Rome, Italy, 3Infectious Diseases Unit, Sapienza University, Latina, Italy

Abstract
Abstract
Poster
Poster
Audio
Audio

P 62Evaluation of Patient-Reported Outcomes (PROs) and cognitive performance in HIV naïve patients with advanced disease: results from the PRO-Advance study

A.C. Brita, C. Pinnetti, A. Vergori, G. Passavanti, P. Lorenzini, R. Gagliardini, R. Bellagamba, E. Grilli, A. Mondi, S. Grisetti, V. Mazzotta, F. Baldini, A. Giannetti, A. Antinori, S. Cicalini

National Institute for Infectious Diseases, IRCCS, L. Spallanzani - HIV/AIDS Unit, Rome, Italy

Abstract
Abstract
Poster
Poster
Audio
Audio

P 63Cerebrospinal Fluid anti-EBV Viral Capsid Antigen IgG Production associates with poorer Performance in Attention, Memory and Executive functions domains among People living with HIV

M. Trunfio1, A. Sacchi2, D. Vai3, F. Pittaluga2, A. Gaviraghi1, G. Guastamacchia3, G. Di Perri1, R. Cavallo2, S. Bonora1, A. Calcagno1

1Infectious Diseases unit, Amedeo di Savoia hospital, University of Torino, Torino, Italy, 2Microbiology and Virology unit, Città della Salute e della Scienza, University of Torino, Torino, Italy, 3Neurology unit, Maria Vittoria hospital, ASL Città di Torino, Torino, Italy

Abstract
Abstract
Poster
Poster

P 64Cryptococcal meningitis in a young woman HIV late presenter: a case report

V. Fortunato, A. Campagna, L. Iapicco, S. Madonia, R. Santoro, A. Spera, R. Verrioli, A. Masullo

AOU " San Giovanni di Dio E Ruggi D'Aragona" Salerno

Abstract
Abstract
Poster
Poster

Poster: HIV cure

P 65A multidisciplinary approach to imprint a successful long term adherence skill to Antiretroviral Therapy in naive patients: background and preliminary data of a pilot project of the GLAD group

G.C. Orofino1, M. Guastavigna1, M.C. Tettoni2, G. Mosso1, R. Interdonato1, C. Grassone2, R. Casciaro2, G. Cinnirella3, S. Bertini3, M.E. Bersia3, F. Busso4, S. Lupo4, S.Ferrero Merlino4

1Division A of Infectious Diseases, Amedeo di Savoia Hospital, Turin, Italy, 2Unit of Infectious Diseases, Department of Medical Sciences, University of Turin, Turin, Italy, 3Pharmacy Department, Amedeo di Savoia Hospital, Turin, Italy, 4Hospital Clinical Psychology, Amedeo di Savoia Hospital, Turin, Italy

Abstract
Abstract
Poster
Poster

P 66Switching Dolutegravir/Abacavir/Lamivudine single tablet regimen (STR) to a less-costly multi-tablet regimen of Dolutegravir+Abacavir/Lamivudine (generic) in the setting of virologic suppression: data at 48 weeks

S. Gardin, L. Sasset, S. Cavinato, E. Di Meco, A.M. Cattelan

Infectious Diseases Division, Azienda Ospedaliera Padova

Abstract
Abstract
Poster
Poster

P 67Complementary-alternative medicines and self prescribed drugs use in women living with HIV

L. Sasset1, E. Di Meco1, A. Frater1, A. Londero2, R. Luzzati3, V. Vazzoler1, A. Cattelan1

1Infectious Diseases Division, Azienda Ospedaliera di Padova, Italy, 2Infectious Diseases Division, Santa Maria della Misericordia University Hospital, Udine, Italy, 3Department of Infective Diseases, University Hospital of Trieste, Italy

Abstract
Abstract
Poster
Poster

Poster: HIV epidemiology and retention in care

P 68Availability of rapid HIV self-test in Italian pharmacies: a survey

P. Piselli1, C. Cimaglia1, C. Pellegris2, C. Castelli3, V. Calvino4, S. Negri4, S. Penon5, M. Farinella6, E. Bendetti6, E. Teti7, R. Marchetti7, N. Catucci5, F. Laura2, G.M. Corbelli8, L. Solagna8, A. Riccio9, M.G. Di Benedetto5, S. Bellini5, A. Camposeragna10, M.L. Circosta2, F. Corona2, A. Caraglia11, L. Rancilio3, M. Oldrini5, E. Girardi1 for the project “Linkage to Care in HIV: a further piece to the analysis of continuum of care in HIV in Italy”*

1INMI L. Spallanzani IRCCS, Rome, 2CICA, 3Caritas Ambrosiana, Milan, 4ANLAIDS, 5LILA, 6Circolo Mario Mieli, Rome, 7Villa Maraini Onlus, Rome, 8PLUS, rete persone LGBT+ sieropositive, 9NPS, 10CNCA, 12Minister of Health, Rome

Abstract
Abstract
Poster
Poster

P 69REducing LAte Presenters Patients rate in Milan area (RELAPP Study): preliminary results

M. Bonfanti1, T. Quirino2, U. Restelli3, N. Astuti4, M.V. Cossu5, A. De Silvestri6, D. Croce7, G. Rizzardini8

1Centre for Research on Health Economics, Social and Health Care Management, LIUC – Università Cattaneo, Castellanza, Varese, Italy, 2Freelance expert in infectious diseases, 3Centre for Research on Health Economics, Social and Health Care Management, LIUC – Università Cattaneo, Castellanza, Varese, Italy; School of Public Health, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa, 4Department of Infectious Diseases, ASST Fatebenefratelli Sacco, University Hospital, 5Department of Infectious Diseases, ASST Fatebenefratelli Sacco, University Hospital, 6Clinical Epidemiology and Biometrics Service - IRCCS Policlinico San Matteo Foundation, 7Centre for Research on Health Economics, Social and Health Care Management, LIUC – Università Cattaneo, Castellanza, Varese, Italy, 8Department of Infectious Diseases, ASST Fatebenefratelli Sacco, University Hospital; School of Clinical Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa

Abstract
Abstract
Poster
Poster
Audio
Audio

P 70May administering routine HIV test be useful to uncover the iceberg in a University Hospital setting? Our experience

C. Picarelli1, F. Lombardi1, A. Ciccullo1, D. Farinacci1, A. Dusina1, D. Moschese1, A. D’Angelillo1, A. Borghetti2, S. Di Giambenedetto1,2

1Università Cattolica del Sacro Cuore, Roma Italia, Istituto di Clinica Malattie Infettive, 2Fondazione Policlinico Universitario A. Gemelli IRCCS, Roma Italia, UOC malattie infettive

Abstract
Abstract
Poster
Poster

P 71High rates of lost-to-follow-up among naive HIV+ female population: real-life data from UOC "Immunodeficienze e Malattie Infettive di Genere", D. Cotugno Hospital, Naples, 2017-19

V. Rizzo1, F.M. Fusco2, M.A. Carleo1, S. Mascolo1, R. Pisapia3, P. Rosario1, V. Esposito1

1UOC Immunodeficienze e Malattie Infettive di Genere, P.O. “D. Cotugno”, Azienda Ospedaliera dei Colli, Naples, Italy, 2UOC Infezioni Sistemiche e dell’Immunodepresso, P.O. “D. Cotugno”, Azienda Ospedaliera dei Colli, Naples, Italy, 3UOC Malattie Infettive ad indirizzo Neurologico, P.O. “D. Cotugno”, Azienda Ospedaliera dei Colli, Naples, Italy

Abstract
Abstract
Poster
Poster

P 72Risk Factors for Late HIV Presentation in a Tertiary Care University Hospital

C. Rovelli, L. Clerici, N.W. Delfrate, Z. Di Rosa, P.A. Grossi

University of Insubria, Varese

Abstract
Abstract
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Poster

P 73Epidemiology and clinical characteristics of HIV/AIDS among foreign in Campania Region, 2008-19: which differences with Italian population?

F.M. Fusco1, A. Menna2, A. Galano2, A. Laudiero2, A. Mariniello2, M. De Cenzo2, S. Mascolo3, M. Sardo4, R. Viglietti1, G. Parrella1, O. Tambaro1, V. Iodice1, M.A. Pisaturo1, G. Di Flumeri1, E. Manzillo4, V. Esposito3, A. Chirianni1, V. Sangiovanni1

1UOC Infezioni Sistemiche e dell’Immunodepresso, P.O. “D. Cotugno”, Azienda Ospedaliera dei Colli, Naples, Italy, 2Servizio Ospedalizzazione Domiciliare, P.O. “D. Cotugno”, Azienda Ospedaliera dei Colli, Naples, Italy, 3UOC Immunodeficienze e Malattie Infettive di Genere, P.O. “D. Cotugno”, Azienda Ospedaliera dei Colli, Naples, Italy, 4U.O.C. Immunodeficienze e malattie dell’immigrazione, P.O. “D. Cotugno”, Azienda Ospedaliera dei Colli, Naples, Italy

Abstract
Abstract
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Poster

P 74The efficacy of cART regimens and retention in care in an HIV-infected cohort of naïve patients

G. Piazza1, S. Vitale1, S. Meneghetti1, L. Appolloni1, G. Pensalfine1, L. Calza2, M. Morotti1

1Clinical Pharmacy, S. Orsola-Malpighi Polyclinic, Bologna, 2Infectious Disease S. Orsola-Malpighi Polyclinic, Bologna

Abstract
Abstract
Poster
Poster

P 75Characterization of HIV-1 transmission dynamics in North and Central Italy over the years 2012-2019

C. Alteri1,2, R. Scutari3, V. Costabile4, S. Carta2, L. Colagrossi5, C. Gori6, A. Bertoli3,7, N. Orchi8, G. De Carli8, S. Pittalis8, L.G. Chianura9, R. Rossotti9, V. Malagnino10, S. Cicalini11, R. Gagliardini11, A. Latini12, A. Nava1, D. Fanti1, M. Lichtner13, M.C. Moioli9, F. Ceccherini-Silberstein3, E. Girardi14, M.M. Santoro3, M. Andreoni10, M. Puoti9, A. Antinori11, C.F. Perno1,2,6

1Department of Oncology and Hemato-oncology, University of Milan, Milan, Italy, 2Chemical-clinical and Microbiological Analysis, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy, 3Department of Experimental Medicine, University of Rome “Tor Vergata”, Rome, Italy, 4Department of Pathophysiology and Transplantation, University of Milan, Milan, Italy, 5Residency in Microbiology and Virology, University of Milan, Milan, Italy, 6Laboratory of Virology, INMI "Lazzaro Spallanzani"-IRCCS, Rome, Italy, 7Virology Unit, University Hospital “Tor Vergata”, Rome, Italy, 8AIDS Reference Center, INMI "Lazzaro Spallanzani"-IRCCS, Rome, Italy, 9Infectious Diseases, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy, 10Infectious Diseases, University Hospital "Tor Vergata", Rome, Italy, 11Clinical Department, INMI "Lazzaro Spallanzani"-IRCCS, Rome, Italy, 12Unit of Dermatology and Sexually Transmitted Diseases, San Gallicano Dermatological Institute IRCCS, Rome, Italy, 13Infectious Diseases Unit, "Sapienza" University, Polo Pontino, Latina, Italy, 14Clinical Epidemiology, INMI "Lazzaro Spallanzani" IRCCS, Rome, Italy

Abstract
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Poster
Poster

P 76"EXTERNA": QoL Perception in PLWHIV during ID checkup

A. Antonino1, A. Bianchi1, F. Rossi1, S. Bossolasco2, E. Messina2, M. Cernuschi1,2, L. Galli2, A. Poli2, A. Castagna2, N. Gianotti2

1ASA Milano, 2San Luigi(HSR), Milano

Abstract
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Poster
Poster

P 77HIV screening in migrant population living in "ghetti" in Apulia

R. Lattanzio1,3, F. Di Gennaro1,2, A. Volpe3, D.F. Bavaro1, G. Putoto2, C. Marotta2, L. Raho3, R. Laforgia3, S. Lo Caputo4, C. Falanga5, L. Monno1, G. Angarano1, A. Saracino1

1Clinic of Infectious Diseases, University of Bari, Bari, Italy, 2Research Unit, Cuamm Medici con l'Africa, Padova, Veneto, Italy, 3Doctors with Africa CUAMM, Bari, Apulia, Italy, 4Clinic of Infectious Diseases, University of Foggia, Foggia, Italy, 5ANLAIDS Sezione Lombardia, Milan, Italy

Abstract
Abstract
Poster
Poster

P 78Geographic distribution of delayed presentation of HIV infection in HIV Emilia Romagna Surveillance System

V. Borghi1, A. Navarra2, S. Leone2, A. Degli Antoni3, E. Barchi4, L. Sighinolfi5, A. Boschi6, E. Massimiliani7, E. Girardi2, C. Mussini1

1Azienda Ospedaliero Universitaria di Modena, Modena, Italy, 2Istituto Nazionale di Malattie Infettive “L. Spallanzani”, I.R.C.C.S, Roma, Italy, 3Azienda Ospedaliero Universitaria di Parma, Parma, Italy, 4Presidio Ospedaliero Provinciale di Reggio Emilia, Reggio Emilia, Italy, 5Azienda Ospedaliero Universitaria di Ferrara, Ferrara, Italy, 6Azienda Unità Sanitaria Locale della Romagna, Rimini, Italy, 7Regione Emilia Romagna, Servizio Prevenzione Collettiva e Sanità Pubblica, Bologna, Italy

Abstract
Abstract
Poster
Poster

P 79Immunological evolution of a cohort of HIV-2 infected patients: peculiarities of an underestimated infection

B. Fumarola, G. Renisi, S. Calza, S. Renzetti, I. El Hamad, C. Pezzoli, I. Izzo, M. Properzi, M. Degli Antoni, A. Celotti, A. Chiesa, P. Nasta, M. De Francesco, E. Quiros-Roldan, A. Caruso, F.Castelli, E. Focà

Spedali Civili di Brescia, Brescia

Abstract
Abstract
Poster
Poster

P 80HIV testing offer and services to improve linkage to Care in public services for HIV test: a survey

P. Piselli1, C. Cimaglia1, L. Rancilio2, P. Meli3, M. Farinella4, E. Teti5, V. Calvino6, G.M. Corbelli7, A. Camposeragna8, M. Errico9, F. von Schloesser10, M. Breveglieri11, A. Caraglia12, M. Oldrini13, E. Girardi1 for the project “Linkage to Care in HIV: a further piece to the analysis of continuum of care in HIV in Italy”

1INMI “L. Spallanzani” IRCCS, Rome, 2Caritas Ambrosiana, Milan, 3CICA, 4Circolo Mario Mieli, Rome, 5Fondazione Villa Maraini, Rome, 6Anlaids, 7PLUS, 8CNCA, 9NPS Italia, 10Nadir, 11Arcigay, 12Minister of Health, 13LILA, Milan

Abstract
Abstract
Poster
Poster

P 81Gap in care and loss to follow up due to administrative barriers among migrants living with HIV in the city of Padova

E. Di Meco, F. Raumer, S. Gardin, L. Sasset, S. Cavinato, A. Cattelan

Division of Infectious Diseases, Azienda Ospedaliera di Padova, Italy

Abstract
Abstract
Poster
Poster

P 82Long-term survivors in a cohort of HIV+ patients diagnosed between 1985 and 1994: predictive factors associated with more than 25 years of survival

F. Cosentino, L. Anile, M. Ceccarelli, A. Marino, A. Pampaloni, D. Scuderi, M.E. Locatelli, V. Moscatt, M. Gussio, V. Boscia, F. Benanti, R.S. Grasso, A. Onorante, R. Bruno, B. Cacopardo, B.M. Celesia

Unit of Infectious Diseases University of Catania ARNAS Garibaldi, Catania

Abstract
Abstract
Poster
Poster

P 83New diagnoses of HIV infection: what has changed in 10 years

T. Alessandra1, S. Ferrara2, S. Sica2, S.R. Bruno2, R. De Benedictis2, T. Santantonio2, S. Lo Caputo2

1Malattie Infettive ASL Foggia, 2Clinica Malattie Infettive, Università degli Studi di Foggia - Foggia, Italy

Abstract
Abstract
Poster
Poster

Poster: HIV immunology and immune-based therapies

P 84Acne vulgaris as possible Immune Recovery Folliculitis driven by the lymphocyte T CD8+ immunological recovery in naïve and experienced patients

M. Camici1, A. Scarabello2, R. Gagliardini1, A. Antinori1

1HIV/AIDS Clinical Unit, National Institute for Infectious Diseases Lazzaro Spallanzani IRCCS, Rome, Italy, 2Dermatological Clinical Unit, National Institute for Infectious Diseases Lazzaro Spallanzani IRCCS, Rome, Italy

Abstract
Abstract
Poster
Poster

P 85Influence of HLA haplotype on immunological recovery in HIV-infected patients

D. Fiordelisi, R. Casciaro, D.F. Bavaro, G. Angarano, L. Monno, A. Saracino

Azienda Ospedaliero Universitaria Consorziale Policlinico, Bari

Abstract
Abstract
Poster
Poster

Poster: HIV pathogenesis

P 86Oxidative Stress and gut microbiota composition in primary HIV infection

E.S. Cannizzo, E. Merlini, M. Allegrini, G. Ancona, C. Tincati, F. Bai, F. Gelpi, A. d’Arminio Monforte, G. Marchetti

Clinic of Infectious Diseases, Department of Health Sciences, ASST Santi Paolo e Carlo, University of Milan

Abstract
Abstract
Poster
Poster

Poster: HIV prevention (PrEP and PEP)

P 87PrEP awareness and attitudes in a survey among Italianclinicians

A. Ciccullo1, G. Baldin1, S. Rusconi2, G. Sterrantino3, G. Madeddu4, V. Borghi5, C. Fimiani6, I. Uccella7, E. Trecarichi8, B. Rossetti9, F. Vignale10, G. d’Ettorre6, M. Scuderi11, A. Latini12, S. Di Giambenedetto1,13

1Section of Infectious Diseases, Department of Safety and Bioethics, Catholic University of the Sacred Heart, Rome, Italy, 2Infectious Diseases Unit, DIBIC Luigi Sacco, University of Milan, Milan, Italy, 3Infectious Diseases Unit, Department of Clinical and Experimental Medicine, University of Florence, Florence, Italy, 4Department of Medical, Surgical and Experimental Sciences, University of Sassari, Sassari, Italia, 5Clinic of Infectious Diseases, University Hospital, University of Modena and Reggio Emilia, Modena, Italy, 6Department of Public Health and Infectious Diseases, Sapienza University of Rome, Rome, Italy, 7UOC Malattie Infettive, Frosinone, Italy, 8Unit of Infectious and Tropical Diseases, Department of Medical and Surgical Sciences, University 'Magna Graecia', Catanzaro, Italy, 9Hospital Department of Specialized and Internal Medicine, Infectious Diseases Unit, University Hospital of Siena, Siena, Italy, 10Clinic of Infectious Diseases, Department of Medicine and Science of Aging, University "G. d'Annunzio" Chieti-Pescara, Italy, 11Unità di Malattie Infettive, Ospedale San Camillo de Lellis, Rieti, Italia, 12Unit of Dermatology and Sexually Transmitted Diseases, San Gallicano Dermatological Institute IRCCS, Rome, Italy,13UOC Malattie Infettive, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Roma, Italia

Abstract
Abstract
Poster
Poster

P 88PrEP: the stories about who used the therapy

M. Zetti, A. Bianchi, P. Vinti

ASA-Associazione Soilidarietà Aids

Abstract
Abstract
Poster
Poster

P 89Young People Inform Young People - Speak to the students with the Peer Section of the School Project

R. Galipò1, E. Farinola1, A. Ferraroni1, P. Ferri1, N. Orchi2, M. Ghenzer1

1Anlaids Lazio, Rome, 2Infectious Disease Epidemiology Unit - AIDS Reference Centre, National Institute for Infectious Disease “L. Spallanzani” – IRCCS, Rome

Abstract
Abstract
Poster
Poster

P 90Problems and difficulties in the management of a PrEP clinic

A. Franco1, L. Aprea2, R.M. Franco1, T. Pizzella2, M. Sardo2, F. Simioli2, E. Manzillo2

1UOSD Profillassi Post-Esposizione – AORN “Ospedali dei Colli” – Napoli, 2UOC Immunodeficienze e Malattie dell’Emigrazione – AORN “Ospedali dei Colli - Napoli

Abstract
Abstract
Poster
Poster
Audio
Audio

P 91Post-exposure prophylaxis in real life

A. Venturelli1, M. Franzetti2, G.V. Calvino1, C. Balotta1, M. Galli3, B. Marchini1

1Anlaids Onlus, Rome, Italy, 2Infectious Diseases Unit, A. Manzoni Hospital, Lecco, Italy, 3Department of Biomedical and Clinical Sciences, ASST ‘Fatebenefratelli Sacco’, University Of Milan, Italy

Abstract
Abstract
Poster
Poster

P 92Determinants of drug start, schedule change and discontinuation in PrEP users

R. Rossotti, C. Baiguera, M. Merli, M. Colaneri, S. Chiappetta, M.C. Moioli, L.G. Chianura, D. Motta, M. Puoti

Department of Infectious Diseases, ASST Grande Ospedale Metropolitano Niguarda

Abstract
Abstract
Poster
Poster

P 93No increased risk of adverse events and sexually transmitted infections in PrEP users despite the rise in condomless sex

R. Rossotti, C. Baiguera, M. Colaneri, M. Merli, S. Chiappetta, M.C. Moioli, L.G. Chianura, D. Motta, M. Puoti

Department o Infectious Diseases, ASST Grande Ospedale Metropolitano Niguarda

Abstract
Abstract
Poster
Poster

P 94PreP: psychological and emotional aspects

A. Bianchi1,2, A. Tavelli3, M. Lanza1, A. De Bona3, E. Suardi3, P. L. Vinti2, D. Calzavara2, A. Antonino1, F. Rossi1, G. Fracca1, D. Rossotti4, S. Bossolasco5, D. Canetta5, G. Ancona3, M. Cernuschi1,2,5

1ASA. Associazione Solidarietà AIDS, Milan, Italy, 2Milano Checkpoint, Milan, 3San Paolo Hospital, Milan, Italy, 4ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy, 5San Raffaele Hospital, Milano, Italy

Abstract
Abstract
Poster
Poster
Audio
Audio

P 95PrEP use amongst MSM in Italy: data from the EMIS 2017 survey

M. Cordioli1, L. Gios1, M.L. Cosmaro2, M. Breveglieri3, F.M. Nimbi4, G.M. Corbelli5, N. Sherriff6, M. Mirandola1,6

1UOC di Malattie Infettive e Tropicali, Dipartimento di Diagnostica e Sanità Pubblica, Università di Verona / Infectious Diseases Section, Diagnostic and Public Health Department, University of Verona, 2Fondazione Lega Italiana per la Lotta contro l’AIDS – LILA Milano, 3Arcigay, 4Dept of Dynamic and Clinical Psychology, Sapienza University of Rome, 5Plus Network persone LGBT sieropositive, 6School of Health Sciences, University of Brighton, Brighton, UK

Abstract
Abstract
Poster
Poster
Audio
Audio

P 96Pre-Exposure Prophylaxis (PrEP): the one-year experience of the first dedicated service of Tuscany Region in S.M.Annunziata Hospital, Florence

E. Salomoni1, F. Vichi1, F. Baragli1, G.M. Corbelli2, M.A. Di Pietro3, P. Blanc1

1Infectious Diseases Unit, S.M.Annunziata Hospital, Florence, Azienda USL Toscana centro; 2Plus Association, Bologna; 3Coordinator of Infectious Diseases Units of Azienda USL Toscana Centro, S.Jacopo Hospital, Pistoia

Abstract
Abstract
Poster
Poster

P 97In vitro effect of Castanea Sativa Mill. bark extract (ENC®) on HIV-1 infection: a potential microbicide

M. Tamburello1, V. D’Urbano1, M. Micucci2, R. Budriesi2, A. Bertoldi1, A. Primavera1, M.C. Re1, I. Bon1

1Microbiology Section, Department of Experimental, Diagnostic and Specialty Medicine, School of Medicine, University of Bologna, Bologna, Italy, 2Pharmacy and Biotechnology Department, University of Bologna, Bologna, Italy

Abstract
Abstract
Poster
Poster
Audio
Audio

Poster: HIV virology

P 98Undetectable versus low level HIV viremia on patients taking antiretroviral therapy

M. Nofri1, C. Papalini1, G.V. De Socio2, B. Belfiori2, S. Bastianelli1, D. Francisci1

1Clinica di Malattie Infettive, Università degli Studi di Perugia, 2Azienda Ospedaliera S. Maria della Misericordia, Perugia

Abstract
Abstract
Poster
Poster
Audio
Audio

P 99Quantification of total HIV-1 DNA in the peripheral blood of naïve and treated patients

L. Di Sante1, A. Costantini2, R. Longo1, A. Corsi2, P. Sestilli3, S. Caucci1, L. Brescini1, S. Menzo1, P. Bagnarelli1

1Department of Biomedical Sciences and Public Health, Polytechnic University of Marche, Ancona, Italy, 2Department of Molecular and Clinical Sciences, Polytechnic University of Marche, Ancona, Italy, 3Virology Unit, Azienda Ospedaliera Ospedali Riuniti, Ancona, Italy

Abstract
Abstract
Poster
Poster

P 100HIV2-Vpx modulation of MDDCs-CD4+ T cells HIV-1 Trans Infection

G.M. Butta1,2, R. De Francesco1,2, L. Manganaro1,3

1INGM-Istituto Nazionale di Genetica Molecolare, Milan, Italy, 2Department of Pharmacological and Biomolecular Sciences, Università degli Studi di Milano, Milan, Italy, 3Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Infectious Diseases Unit, Department of Internal Medicine, Milan, Italy

Abstract
Abstract
Poster
Poster

P 101New potential anti-HIV agents: the antimicrobial peptide Temporin L

A. Chianese1, C. Zannella1, G. Greco1, V. Valastro1, D. D’orio1, F. Pinto1, S.A. Maiella1, M.V. Morone1, G. Franci2, P. Grieco3, M. Galdiero11

1Department of Experimental. Medicine, Section of Virology and Microbiology University of Campania “Luigi Vanvitelli”, Naples, Italy, 2Department of Medicine, Surgery and Dentistry “Scuola Medica Salernitana”, University of Salerno, Baronissi (SA), Italy, 3Department of Pharmacy, University of Napoli Federico II, Naples, Italy

Abstract
Abstract
Poster
Poster
Audio
Audio

P 102Fast and sensitive qPCR assay for the concomitant quantification of bacterial 16S rDNA and HIV-1 DNA: preliminary data from blood samples of HIV-1 infected patients

C. Orlandi1, E. Merlini2, ES. Cannizzo2, G. Marchetti2, M. Magnani1, A. Casabianca1

1Department of Biomolecular Sciences, University of Urbino "Carlo Bo", 2Clinic of Infectious Diseases ASST Santi Paolo e Carlo, Department of Health Sciences-University of Milan

Abstract
Abstract
Poster
Poster
Audio
Audio

P 103HIV-DNA quantification in PBMC: evaluation of two new real-time PCR commercial test

T. Allice, M.G. Milia, E. Burdino, G. Gregori, G. Morleo, B. Simoncelli, P. Russo, E. Scuccimarra, V. Ghisetti

Laboratory of Microbiology and Virology, ASL Città di Torino, Italy

Abstract
Abstract
Poster
Poster

P 104Influence of HIV-1 V2 domain characteristics on immunological recovery under ART

F. Balena, D.F. Bavaro, A. Ricciardi, E. Pallara, A. Volpe, A. Lagioia, G. Angarano, L. Monno, A. Saracino

Clinica di Malattie Infettive, Bari

Abstract
Abstract
Poster
Poster

P 105Susceptibility to HIV-1 integrase inhibitors in HIV-1 sub-subtype A6 isolates

A. Giannini1, F. Giammarino1, A. Antonova2, E. Ozhmegova2, R. Kaiser3, F. Dragoni1, A. Boccuto1, I. Vicenti1, A. Sönnerborg4,5, M. Bobkova2, M. Zazzi1, F. Saladini1

1Department of Medical Biotechnologies, University of Siena, Italy, 2Gamaleya National Research Center of Epidemiology and Microbiology, Moscow, Russian Federation, 3Institute of Virology, University of Cologne, Faculty of Medicine and University Hospital of Cologne, Germany, 4Division of Clinical Microbiology, Department of Laboratory Medicine, Karolinska Institutet, Sweden, 5Department of Medicine Huddinge, Division of Infectious Diseases, Karolinska Institutet, Sweden

Abstract
Abstract
Poster
Poster

P 106Residual phenotypic susceptibility to second generation NNRTI in multidrug resistant HIV-1 from the PRESTIGIO Registry

F. Saladini1, F. Giammarino1, F. Maggiolo2, M. Ferrara3, G. Cenderello4, B.M. Celesia5, F. Martellotta6, V. Spagnuolo7, G.M. Corbelli8, N. Gianotti9, M.M. Santoro10, S. Rusconi11, M. Zazzi1, A. Castagna7,9, for the PRESTIGIO STUDY GROUP

1University of Siena, Siena, Italy, 2Azienda Ospedaliera Papa Giovanni XXIII, Bergamo, Italy, 3Amedeo di Savoia Hospital, Torino, Italy, 4Galliera Hospital, Genoa, Italy, 5Garibaldi Hospital, Catania, Italy, 6Centro di riferimento oncologico, Aviano, Italy, 7San Raffaele Vita-Salute University, Milan, Italy, 8Plus, Bologna, Italy, 9San Raffaele Scientific Institute, Milan, Italy, 10University of Rome Tor Vergata, Rome, Italy, 11DIBIC Luigi Sacco, University of Milan, Italy

Abstract
Abstract
Poster
Poster

P 107In vitro activity of Islatravir against HIV-1 mutants harboring multiple NRTI resistance mutations

F. Giammarino1, F. Saladini1, M. Tavio2, A.M. Cattelan3, B. Menzaghi4, E. Garlassi5, F. Ortu6, G.M. Corbelli7, A. Poli8, M.M. Santoro9, M. Zazzi1, A. Castagna8,10, for the PRESTIGIO STUDY GROUP

1Department of Medical Biotechnologies, University of Siena, Siena, Italy, 2Infectious Diseases Unit, Azienda Ospedaliero Universitaria Ospedali Riuniti, Ancona, Italy, 3Unit of Infectious Diseases, Department of Internal Medicine, Azienda Ospedaliera-Universitaria di Padova, Padova, Italy, 4Busto Arsizio Hospital, ASST Valle Olona, Infectious Diseases, Busto Arsizio, Italy, 5Infectious Disease Unit, Arcispedale Santa Maria Nuova, Azienda USL-IRCCS, Reggio Emilia, Italy, 6Immunology Department, AOU Cagliari, Italy, 7PLUS, Bologna, Italy, 8Department of Infectious Diseases, IRCCS San Raffaele Scientific Institute, Milan, Italy, 9Department of Experimental Medicine, University of Rome "Tor Vergata", Rome, Italy, 10San Raffaele Vita-Salute University, Milan, Italy

Abstract
Abstract
Poster
Poster

P 108Does HLA-C binding stability affect HIV-1 infection?

S. Mutascio, A. Bonomini, C. Stefani, D. Gibellini, M.G. Romanelli, D. Zipeto

University of Verona

Abstract
Abstract
Poster
Poster

P 109Genotipic Resistance test in rapid ART era

M. Rizzo1, L. Montemurro1, M.R. Lipsi2, I.R. Bottalico1, J.F, Fiore1, S. Ferrara1, S. Lo Caputo1 , T.A Santantonio1

1Clinica Malattie Infettive, Università degli Studi di Foggia - Foggia, Italy, 2II Laboratorio analisi sezione Biologia Molecolare AOU Ospedali Riuniti di Foggia

Abstract
Abstract
Poster
Poster

Poster: HIV-associated tuberculosis

P 110Tuberculous and non tuberculous mycobacterial extra-pulmonary infections in HIV

F. Bulla1, P. Scerbo1, S. Nisticò2, L. Cosco1

1S.O.C. Malattie Infettive A.O. “Pugliese-Ciaccio” Catanzaro, 2S.O.C. Microbiologia A.O. “Pugliese-Ciaccio” Catanzaro

Abstract
Abstract
Poster
Poster

Poster: Issues on antiretroviral therapy

P 111Short-Cycle Therapy comprising a lamivudine and dolutegravir regimen of 5 days on and 2 off in a small cohort of suppressed HIV-infected patients

M. Lanzafame1, D. Luise2, S. Rizzardo2, L. Lambertenghi2, G. Be2, L. Motta2, D. Piacentini2, M. Cordioli2, E. Lattuada2

1Unità Semplice Organizzativa “Diagnosi e Terapia dell’infezione da HIV”, Ospedale Policlinico “G.B. Rossi”, Verona, 2Unità Complessa di Malattie Infettive, Ospedale Policlinico “G.B. Rossi”, Verona

Abstract
Abstract
Poster
Poster
Audio
Audio

P 112Are 2-drug regimens with lamivudine plus boosted-PI still a feasible option in the era of integrase inhibitors? A multicenter analysis

A. Ciccullo1, G. Baldin1,2, V. Borghi3, M. Colafigli4, G. Sterrantino5, A. Latini4, C. Mussini3, S. Di Giambenedetto1,6

1Institute of Clinical Infectious Diseases, Catholic University of the Sacred Heart, Rome, Italy, 2Mater Olbia Hospital, Olbia, Italy, 3Azienda Ospedaliero Universitaria di Modena, Clinica Malattie Infettive e Tropicali, Modena, Italy, 4Infectious Dermatology and Allergology Unit, S. Gallicano Institute IRCCS, Rome, Italy, 5Infectious Diseases Unit, Department of Clinical and Experimental Medicine, University of Florence, Florence, Italy, 6UOC Malattie Infettive, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy

Abstract
Abstract
Poster
Poster

P 113HIV-DNA decay in ART-naïve patients starting a DTG-based dual vs triple therapy

F. Lombardi1, R. Scutari2, S. Belmonti1, C. Stingone3, A. Ciccullo1, V. Svicher3, A. Borghetti4, L. Sarmati3, G. Baldin1, C. Alteri5, M. Fabbiani6, C. F. Perno5, M. Andreoni3, S. Di Giambenedetto1,4, F. Ceccherini-Silberstein3

1Università Cattolica del Sacro Cuore, Dipartimento di Sicurezza e Bioetica Sezione Malattie Infettive, Rome, Italy, 2Department of Experimental Medicine, Tor Vergata University, Rome, Italy, 3Department of System Medicine, Clinical Infectious Diseases, Tor Vergata University, Rome, Italy, 4Fondazione Policlinico Universitario A. Gemelli IRCCS, Roma Italia, UOC malattie infettive, 5Department of Oncology and Hemato-oncology, University of Milan, Italy, 6UOC Malattie Infettive e Tropicali, Azienda Ospedaliero-Universitaria Senese

Abstract
Abstract
Poster
Poster
Audio
Audio

P 114Side effects detected in HIV-positive patients depending on the ART regimen

Z. Akhmedjanova1, D. Karimov2, D. Urunova3, M. Mirhoshimov4, D. Akhmedjanov5

1Institute of Immunology and Genomics of the Academy of Sciences of the Republic of Uzbekistan, Tashkent, 2Tashkent Medical Academy, Tashkent,3Tashkent Institute for Advanced Training of Physicians, Tashkent, 4Tashkent Pediatric Medical Institute, Tashkent, 5The University of Toronto, Toronto

Abstract
Abstract
Poster
Poster

P 115Safety and tolerability of tenofovir alafenamide (TAF) on bone mineralization and renal function in a cohort of young adults with HIV infection

A. Manzo1, S. Lazzarin1, K. Maruca2, L. Legramandi3, E. Longoni1, P. Erba1, F.W. Basile1, G.V. Zuccotti4, S. Mora2, V. Giacomet1

1University of Milan, Italy, Paediatric Infectious Disease Unit, ASST-FBF-SACCO, Milan, Italy, 2IRCCS San Raffaele Scientific Institute, Laboratory of Paediatric Endocrinology, Milan, Italy, 3Unit of Statistics – Laboratory of Methodology for Clinical Research, IRCCS Istituto di Ricerche Farmacologiche Mario Negri, Milan, Italy, 4University of Milan, Italy, Children Hospital V. Buzzi, ASST-FBF-SACCO, Milan, Italy

Abstract
Abstract
Poster
Poster
Audio
Audio

P 116A rare case of acute tubular necrosis tenofovir alafenamide-related

M. Pontolillo, L. Caiazzo, L. Piscitani, A. Auricchio, C. Ucciferri, F. Vignale, K. Falasca, J. Vecchiet

Clinic of Infectious Diseases, “G. d’Annunzio” University Chieti-Pescara, Chieti, Italy, Nephrology Department, “G. d’Annunzio” University Chieti-Pescara, Chieti, Italy, Department of Medicine and Health Sciences, University of Molise, Campobasso, Italy

Abstract
Abstract
Poster
Poster
Audio
Audio

P 117New cases of diabetes dolutegravir-associated in HIV patients: a case series

V. Cogliandro, G. Lapadula, N. Squillace, A. Soria, P. Vitiello, M. Rossi, E. Colella, P. Columpsi, G.M. Migliorino

ASST Monza, Ospedale San Gerardo, Unità Operativa di Malattie Infettive, Monza

Abstract
Abstract
Poster
Poster

P 118Reduced Bone catabolism and inflammation in patients switching to TAF-containing cART

E.S. Cannizzo1, A Cozzi-Lepri2, F. Ceccherini S.3, R. Scutari3, C. Alteri4, A. Tavelli5, D. Bernacchia6, E. Merlini1, A. Castagna7, A. Antinori8, A. d’Arminio Monforte1, G. Marchetti1 on behalf of Icona and TAF-Icona Study Groups

1Clinic of Infectious Diseases, Dept Health Sciences, University of Milan, ASST Santi Paolo e Carlo, Milan, Italy, 2Centre for Clinical Research, Epidemiology, Modelling and Evaluation (CREME) Institute for Global Health UCL, London, UK, 3Dept of Experimental Medicine, University of Rome Tor Vergata, Rome, Italy, 4Dept of Oncology and Hemato-Oncology, University of Milan, Milan, Italy, 5Icona Foundation, Milan, Italy, 6Infectious Diseases Unit, ASST FBF-Sacco, DIBIC "L. Sacco", University of Milan, Milan, Italy, 7Division of Infectious Diseases, IRCCS San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan, Italy, 8HIV/AIDS Clinical Unit, National Institute for Infectious Diseases Lazzaro Spallanzani IRCCS, Rome, Italy

Abstract
Abstract
Poster
Poster

P 119Viral outcome on tailored treatment strategyusing cost saving antiretroviral (ARV)

S.T. Kiros1, P. Nizzoli3, M. Pittorru3, L. Rabatti3, M.G. Colao4, D. Bartolozzi2

1Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy, 2Infectious and Tropical Diseases Unit, Careggi University Hospital, Florence, Italy, 3Local health pharmaceutical department of Central Tuscany, 4Microbiology and Virology laboratory, Careggi University Hospital, Florence, Italy

Abstract
Abstract
Poster
Poster

P 120The need for reducing both ARV and medicine-taking burdens among Italian PLHIV - Findings from the Positive Perspectives 2 Study

G.M. Corbelli1, S. Marcotullio2, P. Rizzini2, P. de los Rios3, A. Appiah4

1Plus Onlus, Bologna, Italy, 2ViiV Healthcare Verona VR, Italy, 3ViiV Healthcare Laval, Quebec, Canada, 4ViiV Healthcare Brentford, UK

Abstract
Abstract
Poster
Poster
Audio
Audio

P 121Switch to darunavir/cobicistat/emtricitabine/tenofovir alafenamide in HIV-infected patients not receiving protease inhibitors-based regimens

M. Ranzenigo1,2, N. Gianotti2, L. Galli2, A. Poli2, A. Mastrangelo1,2, C. Muccini1,2, E. Bruzzesi1,2, M. Chiurlo1,2, S. Nozza2, S. Bossolasco2, V. Spagnuolo2, D. Mancusi3, R. Termini3, E. Carini2, A. Lazzarin2, A. Castagna1,2

1Vita-Salute San Raffaele University, Milan, Italy, 2Infectious Diseases, IRCCS San Raffaele Scientific Institute, Milan, Italy, 3Medical Affairs Department, Infectious Disease & PAH, Janssen-Cilag SpA, Cologno Monzese

Abstract
Abstract
Poster
Poster
Audio
Audio

P 122Nevirapine-based therapy in the twenty-first century: still an effective and safe long-term choice

S. Casolari1, G. Fabbri1, P. Tatarelli1, M. Fantini2, E. Fabbri2, V. Sambri3, P. Bassi1

1Infectious Diseases Unit, Santa Maria delle Croci Hospital, Ravenna, AUSL Romagna, Italy, 2Clinical and organizational research unit, AUSL Romagna, Italy, 3Unit of Microbiology, The Great Romagna Hub Laboratory, Pievesestina, Forlì-Cesena, Italy

Abstract
Abstract
Poster
Poster

P 123Switch to dual therapy (3tc+dtg or rpv+dtg) in a cohort of people living with HIV: experience from real life

F. Paciosi, E. Schiaroli, G.V. De Socio, S. Bastianelli, S. Pierucci, C. Busti, D. Francisci

Unit of Infectious Diseases, Department of Medicine, University of Perugia, Perugia, Italy

Abstract
Abstract
Poster
Poster

P 124Changes in lipid profile and subclinical atherosclerosis after switching to tenofovir alafenamide (TAF) containing antiretroviral regimens in people living with HIV

M. Spaziante1, E. Biliotti1, A. Concistrè2, G. Iaiani1, M. Santori1, F. Tamburini1, F. Rufi1, R. Esvan1, C. Letizia2, P. Rucci3, G. Taliani1

1Department of Translational and Precision Medicine, Sapienza University of Rome, Rome, Italy, 2Unit of Secondary Hypertension, Department of Internal Medicine and Medical Specialties, Sapienza University of Rome, Rome, Italy, 3Department of Biomedical and Neuromotor Sciences, University of Bologna, Bologna, Italy

Abstract
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P 125An early proactive switch to elvitegravir/cobicistat/emtricitabine/tenofovir alafenamide (E/C/T/TAF) is effective in maintaining virologic control, reducing low level viral replication and continuing immunological recovery in patients with a primary HIV-1 infection (PHI). An interim analysis of a phase IV clinical trial (ESTER study)

M. Camici1, C. Pinnetti1, R. Gagliardini1, A. Amendola2, I. Abbate2, G. Rozera2, G. Passavanti1, A. Brita1, S. Ottou1, A. Vergori1, M.M. Plazzi1, R. Bellagamba1, S. Cicalini1, M.R. Capobianchi2, A. Antinori1, A. Mondi1

1HIV/AIDS Clinical Unit, National Institute for Infectious Diseases Lazzaro Spallanzani IRCCS, Rome, Italy, 2Laboratory of Virology, National Institute for Infectious Diseases Lazzaro Spallanzani IRCCS, Rome, Italy

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Poster

P 126Efficacy of dolutegravir versus darunavir in first-line regimens according to resistance mutations and viral subtype

A. Borghetti1, C. Picarelli2, A. Ciccullo2, V. Borghi3, P. Laghetti4, S. Rusconi5,6, L. Monno7, W. Gennari3, F. Maggiolo8, B. Bruzzone9, I. Vicenti10, A. Callegaro11, A. Di Biagio12, M. Zazzi10, S. Di Giambenedetto1,2

1Fondazione Policlinico Universitario A. Gemelli IRCCS, Roma Italia, UOC malattie infettive, 2Università Cattolica del Sacro Cuore, Roma Italia, Istituto di Clinica Malattie Infettive, 3Clinica delle Malattie Infettive e Tropicali dell'Università di Modena e Reggio Emilia, Modena, Italy, 4Microbiologia e Virologia, Università degli Studi di Bari, Bari, Italy, 5III Infectious Disease Unit, ASST-FBF-Sacco, Milan, Italy, 6Department of Biomedical and Clinical Sciences DIBIC L. Sacco, University of Milan, Milan, Italy, 7Clinica Malattie Infettive, Università degli Studi di Bari, Bari, Italy, 8Infectious Diseases Unit, Ospedali Riuniti, Bergamo, Italy, 9Hygiene Unit, Policlinico San Martino Hospital, Genoa, Italy, 10Department of Medical Biotechnologies, University of Siena, Siena, Italy, 11Microbiology and Virology Unit, Bergamo Hospital, Bergamo, Italy, 12Infectious Diseases Clinic, Policlinico San Martino Hospital, Department of Health Sciences (DISSAL), University of Genoa, Genova, Italy

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P 127Switch to dolutegravir-based dual therapy: outcomes in ART-experienced patients

G. Tagliaferri, G. Mulè, L. Gazzola, T. Bini, G. Marchetti, A. d’Arminio Monforte

University of Milan, San Paolo Hospital, Milan

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P 128Evaluation of efficacy and durability of raltegravir once-daily: real-life data from an Italian Center

A. Emiliozzi1,2, A. Dusina1, D. Farinacci1, A. D’Angelillo1, A. Ciccullo1, D. Moschese1, C. Picarelli1, G. Baldin1, S. Lamonica1, F. Lombardi1, A. Borghetti3, S. Di Giambenedetto1,3

1Università Cattolica del Sacro Cuore, Dipartimento di Sicurezza e Bioetica Sezione Malattie Infettive, Roma, Italy, 2UOC Malattie Infettive e Tropicali, Dipartimento di Biotecnologie Mediche, Università di Siena, Siena, Italy, 3Fondazione Policlinico Universitario A. Gemelli IRCCS, Roma Italia, UOC Malattie Infettive

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P 129Impact on CD4 count and CD4/CD8 ratio of 3 different integrase inhibitor-based regimens in naïve and experienced patients

V. Moscatt1, M. Ceccarelli1, R. Bruno1, A. Pampaloni1, A. Marino1, M.E. Locatelli1, F. Cosentino1, V. Boscia1, G. Bruno1, M. Gussio1, B. Busà2, G. Nunnari3, B. Cacopardo1, B.M. Celesia1

1Unit of Infectious Diseases University of Catania ARNAS Garibaldi, Catania, 2Unit of Hospital Pharmacy ARNAS Garibaldi, Catania, 3Unit of Infectious Diseases University of Messina Policlinico Universitario G. Martino, Messina

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P 130Alteration of serum lipid profiles in HIV/HCV co-infected patients under treatment with HAART/DAAs combined therapy

A.M. Spera1, V. Fortunato2, S. Madonia2, A. d’Agostino4, R. Santoro2, G. Galasso3, A. Masullo2, P. Pagliano1

1Infectious Disease Department - Universitary Hospital OO RR San Giovanni di Dio e Ruggi d'Aragona (SA), 2Infectious Disease Department - OO RR San Giovanni di Dio e Ruggi d'Aragona (SA), 3Cardiology Department - Universitary Hospital OO RR San Giovanni di Dio e Ruggi d'Aragona (SA), 4Medical Student - Universitary Hospital OO RR San Giovanni di Dio e Ruggi d'Aragona (SA)

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P 131Plasma viral load decay in first-time INSTI-users. A comparison between raltegravir, elvitegravir/cobicistat and dolutegravir

M. Ceccarelli1, V. Moscatt1, E. Venanzi Rullo2,3, G. Nunnari2, F. Cosentino1, A. Marino1, A. Pampaloni1, D. Scuderi1, R. Bruno1, B. Cacopardo1, B.M. Celesia1

1Unit of Infectious Diseases University of Catania ARNAS Garibaldi, Catania, 2Unit of Infectious Diseases, University of Messina, Policlinico Universitario "G. Martino", Messina, 3University of Pennsylvania, Philadelphia, US

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P 132Metabolic profile changes after switching from a PI- to an INI-based regimen in the maintenance treatment of HIV infection

Z. Pasquini1,2, A. Polenta1,2, M. Malandrino1, B. Canovari2, E. Orsetti3, F. Mecozzi3, A. Mataloni4, G. Amadio3, O. Cirioni1, A. Costantini4, M. Tavio4, A. Giacometti1, F. Barchiesi1,2

1Infectious Diseases Clinic, Department of Biological Sciences and Public Health, Marche Polytechnic University, Ancona, Italy, 2Infectious Diseases Unit, Azienda Ospedaliera Ospedali Riuniti Marche Nord, Pesaro, Italy, 3Unit of Infective diseases, Hospital of Fermo, Italy, 4Clinical Immunology Unit, Department of Clinical and Molecular Sciences, Università Politecnica delle Marche, Ancona, Italy, 5Division of Infectious Diseases, Azienda Ospedaliero Universitaria Ospedali Riuniti, Ancona, Italy

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Audio
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P 133Evaluation of lipid profile in HIV naive patients, treated by TAF-based regimens

S. Martini1, P. Maggi1, C. Gervasoni2, L. Onorato1, S. Ferrara3, L. Alessio4, C. Bellacosa5, V. Esposito6, G. Di Filippo7, A. Masiello8, A. Maddaloni9, R. Santoro10, G. D’Alessio11,S.R. Bruno3, V. Rizzo6, S. Parente7, A. Iodice4, N. Coppola1,4

1Infectious Disease, University of Campania, Luigi Vanvitelli, 2ASST FBF Sacco of Milano, 3University of studies of Foggia, 4AORN Sant’Anna e San Sebastiano of Caserta, 5University of studies of Bari, 6IV Division AORN dei Colli, 7University Federico II of Naples, 8AO San Giuseppe Moscati of Avellino, 9VII Divisione AORN dei Colli, 10AOU San Giovanni di Dio e Ruggi d’Aragona of Salerno, 11AORN San Pio of Benevento

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Poster: Management and treatment of viral hepatitis

P 134Younger Age, Male Gender and HCC presence are Associated to anti HCV-DAA failure

U. Visco-Comandini, Italy, R. Lionetti, Italy, C. Taibi, Italy, M. Zaccarelli, Italy, A. Vergori, Italy, M.R. Capobianchi, Italy, A.R. Garbuglia, Italy, G. D’Offizi, Italy

Infectious Disease and Hepatology Division. National Institute for Infectious Diseases Lazzaro Spallanzani, Rome Italy

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Poster

P 135Reactivation of occult HBV infection in HIV patients treated with direct-acting antivirals for chronic hepatitis C: a retrospective study

V. Guardigni1, B. Granozzi1, L. Badia1, S. Galli2, G. Piazza3, I. Bon2, P. Viale1, M.C. Re2, G. Verucchi1

1Department of Medical and Surgical Sciences, University of Bologna, Italy, 2Department of Specialistic, Diagnostic and Experimental Medicine, University of Bologna, Italy, 3Clinical Pharmacy, S. Orsola-Malpighi Polyclinic, Bologna, Italy

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P 136DAA failure in HCV genotype not 1: virological features and efficacy of re-treatment

L. Occhiello1, M. Pisaturo1*, M. Starace1*, C. Minichini1, A. Di Fraia1, S. De Pascalis2, M. Macera2, V. Messina3, V. Sangiovanni4, E. Claar5, D. Precone6, G. Stornaiuolo2, M.Stanzione2, I. Gentile8, G. Brancaccio2, S. Martini9, A. Masiello10, A. Salomone Megna11, C. Coppola12, A. Federico13, E. Sagnelli1, M. Persico14, A. Galeota Lanza15, A. Marrone16, G.B. Gaeta2, N. Coppola1,3

1Laboratory for the identification of prognostic factors of response to the treatment against infectious diseases, University of Campania "L. Vanvitelli", Napoli, Italy, 2Infectious Diseases and Viral Hepatitis, Department of Mental and Physical Health and Preventive Medicine, University of Campania "L. Vanvitelli", Napoli, Italy, 3Infectious Diseases Unit, A.O. S Anna e S Sebastiano Caserta, Italy, 4Third Infectious Diseases Unit, AORN dei Colli, P.O. Cotugno, Naples, Italy, 5Internal Medicine Unit, Evangelical Hospital Villa Betania Naples, Italy, 6Internal Medicine Unit A.O Sarno, Sarno (SA) Campania L. Vanvitelli, & Infectious and Transplant Medicine, AORN Ospedali dei Colli- Monaldi Hospital, Naples, Italy, 7Gastroenterology Unit, AOU San Giovanni di Dio Ruggi d'Aragona, Salerno Italy, 8Infectious Diseases Unit, University Federico II, Naples, Italy, 9HIV Unit, University of Campania L. Vanvitelli, Naples, Italy, 10Infectious Diseases Unit, A.O S.G. Moscati, Avellino Italy, 11Infectious Diseases Unit, A. O G.Rummo, Benevento, 12Hepatology Unit, Gragnano Hospital, Gragnano, 13Internal Medicine and Hepatology Department of Clinical and Experimental Medicine, University of Campania "L. Vanvitelli", 14Internal Medicine and Hepatology Unit, PO G. Da Procida-AOU- San Giovanni e Ruggi D'Aragona, University of Salerno, 15Hepatology Unit, Cardarelli Hospital, Naples, Italy, 16Department of Medical, Surgical, Neurological, Metabolic, and Geriatric Sciences, University of Campania "L. Vanvitelli

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P 137Virological features and efficacy of re-treatment in HCV patients: a real experience in Southern Italy

C. Minichini1, M. Pisaturo1, M. Starace1, A. DiFraia1, S. De Pascalis2, M. Macera2, V. Messina3, V. Sangiovanni4, E. Claar5, D. Precone6, G. Stornaiuolo2, M. Stanzione2, I. Gentile8, G. Brancaccio2, S. Martini9, A. Masiello10, A. Salomone Megna11, C. Coppola12, A. Federico13, E. Sagnelli1, M. Persico14, A. Galeota Lanza15, A. Marrone16, G.B.Gaeta2, N. Coppola1,3

1Laboratory for the identification of prognostic factors of response to the treatment against infectious diseases, University of Campania "L. Vanvitelli", Napoli, Italy, 2Infectious Diseases and Viral Hepatitis, Department of Mental and Physical Health and Preventive Medicine, University of Campania "L. Vanvitelli", Napoli, Italy, 3Infectious Diseases Unit, A.O. S Anna e S Sebastiano Caserta, Italy, 4Third Infectious Diseases Unit, AORN deiColli, P.O. Cotugno, Naples, Italy, 5Internal Medicine Unit, Evangelical Hospital Villa Betania Naples, Italy, 6Internal Medicine Unit A.O Sarno, Sarno (SA) Campania L. Vanvitelli, &Infectious and Transplant Medicine, AORN Ospedali dei Colli- Monaldi Hospital, Naples, Italy, 7Gastroenterology Unit, AOU San Giovanni di Dio Ruggi d'Aragona, Salerno Italy, 8Infectious Diseases Unit, University Federico II, Naples, Italy, 9HIV Unit, University of Campania L.Vanvitelli, Naples, Italy, 10Infectious Diseases Unit, A.O S.G. Moscati, Avellino Italy, 11Infectious Diseases Unit, A. OG.Rummo, Benevento, 12Hepatology Unit, Gragnano Hospital, Gragnano, 13Internal Medicine and Hepatology Department of Clinical and Experimental Medicine, University of Campania "L. Vanvitelli", 14Internal Medicine and Hepatology Unit, PO G. Da Procida-AOU- San Giovanni e Ruggi D'Aragona,University of Salerno, 15Hepatology Unit,Cardarelli Hospital, Naples, Italy, 16Department of Medical, Surgical, Neurological, Metabolic, and Geriatric Sciences, University of Campania "L. Vanvitelli

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P 138Overall survival at 3, 5 and 10 years of HIV-positive patients who underwent liver transplantation at the University Hospital of Ancona

V. Iencinella1, S. Castelletti1, R. Del Gobbo1, A. Marigliano1, A. Mataloni1, A. Riva1, S. Staffolani1, L. Brescini2, A. Fiorentini2, D. Nicolini3, M. Vivarelli3, P. Barbadoro4, M. Tavio5

1Malattie Infettive Emergenti e degli Immunodepressi - Ospedali Riuniti di Ancona, 2Clinica di Malattie Infettive tropicali, parassitologia, epatiti croniche - Ospedali Riuniti di Ancona, 3Clinica di chirurgia epatobiliare, pancreatica e dei trapianti - Ospedali Riuniti di Ancona, 4SOD Igiene Ospedaliera - Ospedali Riuniti di Ancona, 5Malattie Infettive Emergenti e degli Immunodepressi - Ospedali Riuniti di Ancona

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Poster

P 139Viro-immunological and histological characterization of a case of HBV-related hepatitis with immune reconstitution inflammatory syndrome after treatment initiation for HBV/HIV-1 co-infection with bictegravir/emtricitabine/tenofovir alafenamide

M. Iannetta1, L. Campogiani1, A. Crea1, A. Di Lorenzo1, E. Teti1, V. Malagnino1, C. Cerva1, G. Palmieri2, C. Cimino2, V. Svicher3, L. Piermatteo3, R. Salpini3, M.A. Zingaropoli4, M.R. Ciardi4, C.M. Mastroianni4, M. Andreoni1, L. Sarmati1

1Department of System Medicine, Tor Vergata University, Rome, Italy, 2Department of Biomedicine and Prevention, Tor Vergata University, Rome, Italy, 3Department of Experimental Medicine and Surgery, Tor Vergata University, Rome, Italy, 4Department of Public Health and Infectious Diseases, Sapienza University, Rome, Italy

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Audio

P 140Indirect hyperbilirubinemia and jaundice during chronic hepatitis C in an HIV-infected patient treated with glecaprevir/pibrentasvir (GLE/PIB) and antiretroviral therapy (ART). The first reported case in Italy

A. Mastroianni1, S. Greco1, G. Apuzzo1, S. De Santis1, V. Vangeli1, G. Guadagnino1, M.V. Mauro2, S. Bonora3, A. De Nicolò4, A. D'Avolio4

1UOC Malattie Infettive e Tropicali, Azienda Ospedaliera di Cosenza, Cosenza, 2UOC Microbiologia e Virologia, Azienda Ospedaliera di Cosenza, Cosenza, 3Clinica delle Malattie Infettive, Università degli Studi di Torino, Torino, 4Laboratorio di Farmacologia e Farmacogenetica, TDM Unit, Università degli Studi di Torino, Torino

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Poster

P 141Current management of hepatitis B in sclerosis patients treated with disease-modify therapies

P. Pasculli1, M.A. Zingaropoli1, M. Iannetta2, V. Perri1, F. Pauri3, M. Altieri3, A. Conte4, C.M. Mastroianni1, M.R. Ciardi1

1Department of Public Health and Infectious Diseases, Sapienza University of Rome, Rome, Italy, 2Department of System Medicine, Tor Vergata University of Rome, Rome, Italy, 3Department of Human Neurosciences, Sapienza University of Rome, Rome, Italy, 4IRCCS Neuromed, Pozzilli (IS), Italy

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Poster

Poster: Management of HIV infection

P 142Effect of 12-week physical activity program on sarcopenia measures in people living with HIV

M. Bonato1, F. Turrini2, L. Galli2, G. Banfi1,2, P. Cinque2

1IRCCS Istituto Ortopedico Galeazzi, Milan Italy, 2IRCCS, San Raffaele Scientific Institute, Milan, Italy, 3Vita-Salute San Raffaele University, Milan, Italy

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Abstract
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Poster

P 143Reasons for starting D/C/F/TAF and characteristics of patients enrolled in an Italian non-interventional study: the DIAMANTE (TMC114FD1HTX4011) study

A. Antinori1, A. Vergori1, G. Rizzardini2, M.V. Cossu2, A. Cascio3, M. Trizzino3, M. Andreoni4, V. Malagnino4, A. Lazzarin5, A. Castagna5,6, F. Castelli7, E. Focà7, A. Uglietti8, R.Termini8, M. Portaro8, D. Mancusi8

1HIV/AIDS Unit, National Institute for Infectious Diseases "Lazzaro Spallanzani" IRCCS, Roma, Italy, 21st Division of Infectious Diseases, ASST Fatebenefratelli Sacco, Milano, Italy, 3Infectious Diseases Clinic, AOU Policlinico “P.Giaccone”, Palermo - Italy, 4Infectious Diseases Clinic, Foundation Policlinico Tor Vergata University Hospital, Rome, Italy, 5IRCSS San Raffaele Scientific Institute, Department of Infectious Diseases, Milan, Italy, 6Università Vita-Salute San Raffaele, Milan, Italy, 7University of Brescia and Spedali Civili General Hospital Department of Infectious and Tropical Diseases Brescia Italy, 8Janssen-Cilag SpA, Medical Affairs Department, Infectious Diseases, Cologno Monzese, Italy

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Poster

P 144HIV-1 DNA quantification: Comparative analysis and validation of two commercial qPCR assays

E. Omiccioli1, E. Carloni1, C. Orlandi2, I. Bon3, A. Bertoldi3, B. Canovari4, Z. Pasquini4,5, F. Barchiesi4,5, V. Ceppetelli1, S. Cicerano1, A. Casabianca2, M. Magnani2

1Diatheva srl, Cartoceto, Fano (PU), 2Dipartimento di Scienze Biomolecolari, Università di Urbino “Carlo Bo”, Urbino (PU), 3Dipartimento di Medicina Specialistica, Diagnostica e Sperimentale, Università di Bologna, Bologna (BO), 4Malattie Infettive, Azienda Ospedaliera Ospedali Riuniti Marche Nord, Pesaro (PU), 5Dipartimento di Scienze Biomediche e Sanità Pubblica, Università Politecnica delle Marche, Clinica Malattie Infettive Ospedali Riuniti di Ancona (AN)

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P 145Intestinal Alkaline Phosphatase levels in HIV infected patients

F. D'Andrea1, C. Micali1, M.G. Coco1, L. Marletta1, D. Larnè1, I.A. Paolucci2, M.R. Lo Presti2, P. Mondello2, P. Scordo2, D. Maranto2, E. Venanzi Rullo1, M. Ceccarelli3, G.F. Pellicanò4, G. Nunnari1

1Dipartimento di Medicina Clinica e Sperimentale, Università degli Studi di Messina, Italia, 2UOC di Malattie Infettive – AOU G. Martino Policlinico di Messina, 3Dipartimento di Medicina Clinica e Sperimentale, ARNAS Garibaldi, Catania, 4Dipartimento di Patologia Umana dell’Adulto e dell’Età Evolutiva “Gaetano Barresi”, Università degli Studi di Messina, Italia

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Poster

P 146Diagnostic performance of different screening strategies for the prevention of HPV-related anal cancer

E.N. Cavallari, L. Santinelli, G.P. Innocenti, G. De Girolamo, M. Ridolfi, C. Pinacchio, L. Celani, G. Ceccarelli, C.M. Mastroianni, G. d'Ettorre

Department of Public Health and Infectious Diseases University of Rome "Sapienza", Rome

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P 147Syphilis in newly HIV-1 diagnosed from 2010 to 2019: a single center report

I.F. Bottalico, M.L. D’Errico, S. Sica, S. Ferrara, J.R. Fiore, S. Lo Caputo, S. Santantonio

Clinica Malattie Infettive, Università degli Studi di Foggia - Foggia, Italy

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Poster

Poster: Non infectious comorbidities in HIV

P 1483TC+DTG versus FTC/TAF plus an integrase inhibitor: comparing changes in bone mineral density

A. Ciccullo1, G. Baldin1,2, V. Borghi3, A.P. Lassandro1, D. Farinacci1, G. Guaraldi3, C. Mussini3, S. Di Giambenedetto1,4

1Institute of Clinical Infectious Diseases, Catholic University of the Sacred Heart, Rome, Italy, 2Mater Olbia Hospital, Olbia, Italy, 3Azienda Ospedaliero Universitaria di Modena, Clinica Malattie Infettive e Tropicali, Modena, Italy, 4UOC Malattie Infettive, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy

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P 149HTA analysis of glatiramer and neuroprotection in HIV-related comorbidities

F. Ferrara1, C. Pelliccia2

1USL Umbria1, Perugia, 2USL Umbria2, Foligno (PG)

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P 150Low Vitamin D concentration is associated with NAFLD and metabolic syndrome in HIV-1-infected patients on combination antiretroviral therapy

L. Calza1, V. Colangeli1, M. Borderi1, D. Testi1, A. Amedeo1, I. Bon2, M.C. Re2, P. Viale1

1Unit of Infectious Diseases, 2Unit of Microbiology, Policlinico S.Orsola, Università di Bologna

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Poster

P 151Cardiovascular disease risk markers in a small cohort of HIV-infetcted patietns switched from abacavir/lamivudine/dolutegravir to lamivudine plus dolutegravir

G. Be2, D. Luise2, S. Rizzardo2, L. Lambertenghi2, L. Motta2, D. Piacentini2, E. Lattuada2, D. Gibellini3 , E. Tacconelli2, M. Lanzafame1

1Unità Semplice Organizzativa “Diagnosi e Terapia dell’infezione da HIV”, Ospedale Policlinico “G.B. Rossi”, Verona, 2Unità Complessa di Malattie Infettive, Ospedale Policlinico “G.B. Rossi”, Verona, 3Sezione di Microbiologia, Dipartimento Diagnostica e Sanità Pubblica, Università di Verona

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P 152Prevalence and incidence of Hepatic Steatosis in SCOLTA cohort

N. Squillace1, E. Ricci2, G. Orofino3, B. Menzaghi4, M. Nofri5, A. Di Biagio6, B.M. Celesia7, G. Pellicanò8, G. Madeddu9, C. Molteni10, R. Gulminetti11, S. Rusconi12, F. Vichi13, L. Valsecchi14, E. Sarchi15, P. Bonfanti9

1Infectious Diseases Clinic, San Gerardo Hospital, University of Milano-Bicocca, Monza, Italy, 2Fondazione ASIA, Milan, Italy, 3Unit of Infectious Diseases, "Divisione A", Amedeo di Savoia Hospital, Torino, Italy, 4Unit of Infectious Diseases, ASST della Valle Olona, Busto Arsizio Hospital, Busto Arsizio, Italy, 5Clinica di Malattie Infettive, Ospedale “Santa Maria della Misericordia” e Università di Perugia, Perugia, Italy, 6Infectious Diseases Clinic, Dept. of Health Sciences, University of Genoa, San Martino Hospital-IRCCS, Genoa, Italy, 7Unit of Infectious Diseases University of Catania ARNAS Garibaldi, Catania, Italy, 8Department of Human Pathology of the Adult and the Developmental Age “G. Barresi”, Unit of Infectious Diseases, University of Messina, Messina, Italy, 9Unit of Infectious and Tropical Diseases, Department of Medical, Surgical and Experimental Sciences, University of Sassari, Sassari, Italy, 10Infectious Disease Unit, Ospedale A. Manzoni, Lecco, Italy, 11Department of Medical Sciences and Infectious Diseases, Fondazione IRCCS Policlinico San Matteo -University of Pavia, Italy, 12Infectious Diseases Unit, DIBIC "Luigi Sacco", University of Milan, Italy, 13Infectious Diseases Unit, Santa Maria Annunziata Hospital, Bagno a Ripoli, Florence, Italy, 141st Department of Infectious Diseases, ASST Fatebenefratelli Sacco, Milan, Italy, 15Infectious Diseases Department, SS Antonio, Biagio, Cesare Arrigo Hospital, Alessandria, Italy

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P 153Factors associated with immunosenescence during early adulthood in HIV-infected patients after durable efficient cART

M. Properzi1, S. Paghera2, L. Imberti2, I. El Hamad1, E. Focà1, M.C. Pezzoli1, I. Izzo1, A. Celotti1, P. Nasta1, B. Fumarola1, M. Degli Antoni1, A. Chiesa1, F. Castelli1, E. Quiros-Roldan1

1Department of Infectious and Tropical Diseases, University of Brescia and ASST Spedali Civili Brescia, Italy, 2Centro di Ricerca Emato-oncologica AIL (CREA), Diagnostic Department, ASST Spedali Civili di Brescia, Italy

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P 154Metabolic changes in HIV-infected patients who continue a two-drug regimen with dolutegravir plus one reverse transcriptase inhibitor or switch to elvitegravir/cobicistat/emtricitabine/tenofovir alafenamide: a randomized study (Be-OnE Study)

M. Chiurlo2, N. Gianotti1, L. Galli1, A. Poli1, L. Della Torre1, C. Vinci1, E. Carini1, S. Nozza1, V. Spagnuolo1,2, C. Muccini2, M. Ranzenigo2, A. Lazzarin1, A. Castagna1,2

1IRCCS Ospedale San Raffaele, Milano, 2Università Vita-Salute San Raffaele, Milano

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P 155A structured smoking cessation intervention in a single centre in patients living with HIV

E. Riguccini1, M. Nofri1, F. Paciosi1, M.B. Pasticci1, M. Dell’Omo2, E. Angelucci2, D. Francisci1, G.V. De Socio1

1Clinica di Malattie Infettive, Ospedale “Santa Maria della Misericordia” e Università di Perugia, Perugia, Italy, 2Sezione di Medicina del Lavoro, Malattie Respiratorie e Tossicologia Professionale ed Ambientale, Ospedale “Santa Maria della Misericordia” e Università di Perugia, Perugia, Italy

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Poster

P 156Physical activity levels in HIV+ cohort of Pavia

S. Ludovisi1, A. Di Filippo1,2, E. Asperges1,2, R. Maserati2, S. Novati2, R. Bruno1,2, M. Mondelli1,2

1Università degli Studi di Pavia, 2Fondazione IRCCS Policlinico San Matteo

Abstract
Abstract
Poster
Poster

P 157Machine learning vs Knowledge based approach in health outcomes' prediction in HIV

G. Guaraldi1, D. Ferrari1,2, J. Milic1,3, A. Caselgrandi1, A. Malagoli1, M. Orsini4, F. D’Imprima1, M. Mancini1, M. Cesari5, R. Martoglia2, G. Lui6, M. Bloch7, C. Mussini1, P. Missier8, F. Mandreoli2

1Modena HIV Metabolic Clinic, University of Modena and Reggio Emilia, Italy, 2Department of Mathematics, University of Modena and Reggio Emilia, Italy, 3Clinical and Experimental Medicine PhD Program, University of Modena and Reggio Emilia, Modena, Italy, 4DataRiver Srl, Italy, 5Geriatric Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milano, Italy, 6Faculty of Medicine, The Chinese University of Hong Kong, 7Holdsworth House Medical Practice, Sydney, NSW, Australia, 8School of Computing, Newcastle University, Newcastle upon Tyne, UK

Abstract
Abstract
Poster
Poster

P 158Use of two drugs regimens (2DR) in a cohort of HIV-infected geriatric patients (GEPPO cohort)

S. Nozza1, S. Calza2, G. Guaraldi3, S. Renzetti3, A. Riva4, G. De Socio5, S. Piconi6, G. Orofino7, G. Madeddu8, G. Di Perri9, A.M. Cattelan10, A. Celotti11, B.M. Celesia12, A. Calcagno9, E. Focà10

1Department of Infectious Diseases, San Raffaele Scientific Institute, Milano, Italy, 2Unit of Biostatistics and Biomathematics & Unit of Bioinformatics, Department of Molecular and Translational Medicine, Università degli Studi di Brescia – Italy, 3University of Modena and Reggio Emilia, Department of Mother, Child and Adult Medicine and Surgical Science, Infectious Disease Clinic, Modena, Italy, 43rd Division of Infectious Diseases, University of Milano, Ospedale L. Sacco, Milano, Italy, 5Department of Infectious Diseases, Azienda Ospedaliero-Universitaria di Perugia, Perugia, Italy, 61st Division of Infectious Diseases Unit, University of Milano, Ospedale L. Sacco, Milano, Italy, 7Unit of Infectious Diseases, 'Divisione A', Ospedale Amedeo di Savoia, ASLTO2, Torino, Italy, 8Infectious and Tropical Diseases Unit, Department of Medical, Surgical and Experimental Sciences, University of Sassari, Sassari, Italy, 9Unit of Infectious Diseases, Department of Medical Sciences, University of Torino, Torino, Italy, 10Unit of Infectious Diseases, Department of Internal Medicine, Azienda Ospedaliero-Universitaria di Padova, Padova, Italy, 11Department of Infectious and Tropical Diseases, University of Brescia, Brescia, Italy, 12Department of Clinical and Molecular Biomedicine, Division of Infectious Diseases, University of Catania, ARNAS Garibaldi, Catania, Italy

Abstract
Abstract
Poster
Poster

P 159Poor concordance between liver stiffness and non-invasive fibrosis scores in HIV-1 monoinfected virologically suppressed patients

V. Borgo1,2, A. Emiliozzi2, M. Colaneri3, G. Zanelli1,2, M. d’Alessandro4, D. Motta3, F. Montagnani1,2, M.C. Moioli3, C. Baiguera3, M. Puoti3, M. Fabbiani1, B. Rossetti1

1Infectious Diseases Unit, Siena University Hospital, Siena, Italy , 2Department of Medical Biotechnologies, University of Siena, Italy, 3Infectious Diseases Unit, Niguarda Hospital, Milan, 4Respiratory Diseases and Lung Transplant Unit, Department of Medical and Surgical Sciences and Neurosciences, Siena University Hospital

Abstract
Abstract
Poster
Poster

P 160Obesity and overweight among people living with HIV in the province of Pavia: a cross-sectional study

A. Di Filippo1,2, S. Ludovisi1, E. Asperges1,2, S. Novati2, R. Maserati2, R. Bruno1,2, U.M. Mondellli1,2

1University of Pavia, Pavia, Italy, 2Fondazione IRCCS Policlinico "San Matteo", Pavia, Italy

Abstract
Abstract
Poster
Poster

P 161Evaluation of resting energy expenditure and body mass composition in a cohort of HIV infected patients on antiretroviral treatment

P. Vitiello1, C. Bertoni2, N. Squillace1, M. Rossi1, F. Sabbatini1, P. Columpsi1, A. Soria1, E. Colella1, M.G. Migliorino1, G. Lapadula1

1Infectious Diseases Unit, S. Gerardo University Hospital, Monza, 2Medical School, Bicocca University, Milan

Abstract
Abstract
Poster
Poster

P 162Archi-Prevaleat project. A National Register of color-Doppler ultrasonography of the epi-aortic vessels in Patients Living with HIV

S. Martini1, S. Ferrara2, C. Bellacosa3, B.M. Celesia4, A. Tartaglia2, P. Maggi1

1Università degli studi della Campania, Luigi Vanvitelli, 2Università degli studi di Foggia, 3Università degli Studi di Bari, 4Università di Catania ARNAS Garibaldi

Abstract
Abstract
Poster
Poster

Poster: Pediatric, adolescent, maternal, fetal aspects

P 163Rethinking the necessity of intrapartum zidovudine administration. A small case series from a single centre in the north of Italy

A. Di Biagio1,2, F. Briano2, R. Pincino2, N. Cusini3, D. Gerbaldo4, A. Allodi5, M. Bassetti1,2

1Infectious Diseases Unit, Policlinico San Martino Hospital, Genoa, 2Department of Health Sciences (DISSAL), University of Genoa, 3Department of Neurosciences, Rehabilitation, Ophtalmology, Genetics, Maternal and Child Health (DiNOGMI), University of Genoa, 4Department of Obstetrics and Gynecology, Policlinico San Martino Hospital, Genoa, 5Neonatal Unit, Policlinico San Martino Hospital, Genoa

Abstract
Abstract
Poster
Poster

Poster: Pharmacology, pharmacogenomics and drug interactions

P 164Antiviral activity of 1-(41-chlorophenyl)-4-(42-methylphenyl)-5,6,7,8-tetrahydro-2a,4a-diazacyclopenta[cd]azulene-2-carboxylic acid derivatives

S. Demchenko1, Yu. Fedchenkova2, O. Bagreeva2, A. Demchenko2

1Institute of Pharmacology and Toxicology of National Academy of Medical Sciences Ukraine, Kyiv, Ukraine, 2Nizhyn Mykola Gogol State University, Nizhyn, Ukraine

Abstract
Abstract
Poster
Poster

P 165Antiviral activity of of 6-(4-methylbenzyl)-3-arylamino-4н-[1,2,4]triazin-5-оne derivatives against yellow fever

E. Novodvorskyi, I. Komarov

Institute of High Technologies Taras Shevchenko National University of Kyiv, Kyiv, Ukraine

Abstract
Abstract
Poster
Poster

P 166Dolutegravir, emtricitabine/tenofovir alafenamide fumarate absorption in a gastrectomized HIV-positive patient

C. Alcantarini, M. Ferrara, M. Tettoni, F. Lipani, S. Biffi, A. Di Stefano, M. Trunfio, A. Lazzaro, V. Avataneo, J. Cusato, A. De Nicolò, A. D’Avolio, A. Calcagno, G. Di Perri, S. Bonora

Unit of Infectious Diseases, Department of Medical Sciences, University of Turin

Abstract
Abstract
Poster
Poster

Poster: Social and behavioural science, marginalized groups, community aspects and community surveys

P 167A survey as a chance of education on U=U in Italian general population

A. Perziano1, S. Patrucco1, G. Orofino2, P. Altini3, G.L. Cipero1, C. Owen4

1Arcobaleno AIDS ODV, Torino, 2Ospedale Amedeo di Savoia, Arcobaleno AIDS ODV, Torino, 3Dipartimento di Scienze della Sanità Pubblica e Pediatriche, Arcobaleno AIDS ODV, Torino, 4Dipartimento di Lingue e Letterature Straniere e Culture Moderne, Arcobaleno AIDS ODV, Torino

Abstract
Abstract
Poster
Poster

P 168Development and management of a web-based system able to collect and analyse data about self-diagnostics HIV test - ULISSE

C. Falanga, D. Mainieri, S. Negri

Anlaids Sezione Lombarda, Milan

Abstract
Abstract
Poster
Poster

P 169HIV prescriptivetrend 2018 vs 2019 in a teaching hospital in Rome

G. Gambarelli1, R. De Feo1, R. Lobello1, C. Bolettieri1. L. Fiorito2, G. Gambarelli3

1A.O.U. Policlinico Umberto Primo Roma, 2Universita' La Sapienza Uniroma1, 3Ospedale S. Eugenio ASL Roma 2

Abstract
Abstract
Poster
Poster

P 170HAARTisticamente An unusual fashion show

A. Infante

Policlinico Tor Vergata di Roma

Abstract
Abstract
Poster
Poster

P 171"La prevenzione va in tournèe" a social experiment and on the field experience on HIV/STIs and social integration

S. Nasta1, C. Nicoara2 , M. Oddo3

1TrinArt ONLUS, Castellammare Del Golfo, 2NPS ONLUS Sicily, Palermo, 3Università degli Studi di Palermo, Palermo

Abstract
Abstract
Poster
Poster

P 172Mono-symptomatic therapeutical group for Chemsex users - an ongoing experience

G. Fracca, M. Manfredini

Asa Milano Onlus, Milano

Abstract
Abstract
Poster
Poster

P 173HIV rapid testing outside healthcare facilities: diagnostic and educational tool

P. Meli1, M. Messina2, P. Pesenti Bolognini3, M. Arlati4, M. Gotti5, R. Carissoli4, F. Maggiolo6

1Caritas Bergamasca & Comunità Emmaus, 2Consiglio di Rappresentanza dei Sindaci & Assessorato alle Politiche Sociali del Comune di Bergamo, 3Croce Rossa Italiana - Comitato di Bergamo OdV, 4ARCIGAY & Cives ARCIGAY Bergamo, 5Associazione La Melarancia, 6ASST Papa Giovanni XXIII, Bergamo

Abstract
Abstract
Poster
Poster
Audio
Audio

P 174Changes in causes of death of people living with HIV in a large teaching hospital in Rome

D. Farinacci1, A. Ciccullo1, A. Dusina1, A. D’Angelillo1, D. Moschese1, C. Picarelli1, A. Borghetti2, S. Di Giambenedetto1,2

1Istituto di Malattie Infettive, Università Cattolica del Sacro Cuore, Roma, Italy, 2Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Roma, Italy

Abstract
Abstract
Poster
Poster

P 175The PLWH perception of long acting injectable therapy

F. von Schloesser, A. Bove, L. Giacomi, D. Osorio, M. Martini

NADIR onlus, Rome

Abstract
Abstract
Poster
Poster

P 176Cohort observational study and HIV brochure in a teaching hospital in Rome

G. Gambarelli1, R. Lobello1, R. De Feo1, C. Bolettieri1, L. Fiorito2, G. Gambarelli3

1Azienda Universitaria Policlinico Umberto 1, Roma, 2Uniroma1 La Sapienza, Roma, 3Ospedale S.Eugenio ASL Roma 2, Roma

Abstract
Abstract
Poster
Poster

P 177HIV Self-Testing in Italy: a usability survey of clients using self-tests at two community organisations

M. Maffeo1,2, M.L. Cosmaro2, M. Kall3, S. Nash3

1Scuola di Specializzazione in Igiene e Medicina Preventiva - Università degli Studi Milano Statale, 2Fondazione Lega Italiana per la Lotta contro l’AIDS - LILA Milano, 3Public Health England

Abstract
Abstract
Poster
Poster

P 178Counselling and HIV rapid test for marginalized groups: data from an Emilia-Romagna Region project*

D. Segala1, A. Zannini2, B. Cantarelli3, A. Giannini4, G. Mattei4, R. Cultrera5, L. Sighinolfi1

1Infectious Disease Dept. Ferrara, 2Addiction treatment service-AUSL Reggio Emilia, 3Addicition treatment service -AUSL Parma, 4Prevention and Public Health Dept. Regione Emilia Romagna, 5Infectious Disese Clinic Ferrara
*Regional project DGR 1698/2015

Abstract
Abstract
Poster
Poster
Audio
Audio

P 179School and HIV. Cognitive and Emotional aspects for effective communication

F. Rossi, A. Bianchi, M. Manfredini, D. Pennisi, D. Zagato, M. Pierini, R. Repossi, E. Garavaglia, M. Cernuschi

ASA ONLUS -Associazione Solidarietà AIDS- Milano

Abstract
Abstract
Poster
Poster
Audio
Audio

P 180Sardinia, first ever institutional Hiv testing and TasP promotion campaign: the communication strategy of Lila Cagliari team

S. Campus, G. Dessì, B. Mocci, A.Pontis

Lila Cagliari, Cagliari

Abstract
Abstract
Poster
Poster
Audio
Audio

P 181"TEST WITH THE STAR": a pre-counselling "dog assistance" pilot project during HIV-HCV screening campaign "1st December World AIDS Day. Communities make the difference. Union makes the difference! HIV LATINA CHALLENGE 2019. U = U"

V. Belvisi1, G. Stella3, R. Marocco1, V.S. Mercurio1, B. Kertusha1,2, L. Fondaco1,2, A. Curtolo1,2, P. Zuccalà1,2, A. Carraro1,2, M. D’Achille1, V. Rossi1, M. Lichtner1,2

1Infectious Diseases Unit, S.M. Goretti Hospital, Latina, 2“Sapienza” University, Rome, 3“Star Golden” E.N.C.I – F.C.I. Golden Retriever Breeding Centre, Nemi

Abstract
Abstract
Poster
Poster
Audio
Audio

P 182Test, condom and chems: how the habits of people in Milan change. A test experience in a premise

A. Bianchi1, F.M. Esposito1, G. Fissore1, A. Antonino1, G. Fracca1, M. Lanza1, F. Rossi1, R. Repossi1, P. Testoni1, D. Zagato1, S. Bossolasco2, M. Cernuschi1,2

1ASA, Associazione Solidarietà AIDS Onlus, Milan, Italy, 2San Raffaele Hospital, Milan, Italy

Abstract
Abstract
Poster
Poster
Audio
Audio

P 183Coming out surrealista

A. Infante, L. Caponera

Policlinico Tor Vergata di Roma

Abstract
Abstract
Poster
Poster

P 184App as tool for Prevention among students: the launch of a new counselling service about HIV/STIs promoted by Anlaids Onlus

M. Pedretti1, E. Zambon2, A. Chinelli3, A. Venturini4, R. Galipò5, V. Calvino6, B. Marchini7

1Anlaids Lombardia, Milano, 2Anlaids Lombardia, Milano, 3Anlaids Liguria, Genova, 4Anlaids Liguria, Genova, 5Anlaids Lazio, Roma, 6Anlaids Onlus, Roma, 7Anlaids Onlus, Roma

Abstract
Abstract
Poster
Poster
Audio
Audio

P 185PrEP between desire and needing: 2020 update

D. Pavia1, L. Gozzi1, A. Toscano1, E. Bacca1,2, G. Cuomo1,2, A. Bignardi3

1Arcigay Modena "Matthew Shepard" (ODV), Modena, Italy, 2Clinica di Malattie Infettive e Tropicali, Azienda Ospedaliero Universitaria, Modena, Italy, 3Arcigay APS, Bologna, Italy

Abstract
Abstract
Poster
Poster
Audio
Audio

P 186Free anonymous HIV Testing and linkage to care activities: data from the Milano Check Point

D. Calzavara1,2, A. Tavelli1,3, A. De Bona1,3, R. Rossotti1,2,4, D. De Cia1,5, I. Gotti1,5, M. Massa1,5, C. Raddato1,6, R. Repossi1,7, J. C. Ritchie1,2, D. Savarino1,8, A. Soldano1,2, A. d’Arminio Monforte1,3, L. Cosmaro1,8, M. Cernuschi1,6,7 for the Milano Checkpoint group

1Associazione Milano Check Point, Milan, Italy, 2Centro d’Iniziativa Gay – Arcigay Milano Onlus, Milan, Italy, 3Clinic of Infectious Diseases, Department of Health Sciences, ASST Santi Paolo e Carlo, University of Milan, Italy, 4Infectious Disease Department ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy, 5Anlaids Sezione Lombardia, Milan, Italy, 6Department of Infectious Diseases, San Raffaele Scientific Institute, Italy, 7ASA - Associazione Solidarietà AIDS Onlus, Milan, Italy, 8Fondazione LILA Milano Onlus, Milano

Abstract
Abstract
Poster
Poster
Audio
Audio

P 187Pleasure and sociality as drivers of chemsex among Italian gay men living with HIV

C. Di Feliciantonio

Manchester Metropolitan University & University of Leicester (UK)

Abstract
Abstract
Poster
Poster

P 188The multidisciplinary (MD) HPV group in Azienda Ospedaliera Universitaria Pisana (AOUP). Impact of HIV-HPV sinergy. Preliminary data analysis

P. Mazzetti1, E. Balestri1, S. Verdenelli2, L. DelBono2, C. Menconi3, I. Marchetti4, V. Seccia5, C. Cambi5, P. Cuttano6 , F. Maggi1, S. Esin7, A. Gallo8, A.G. Naccarato4, G. Naldini3, F. Menichetti2, M. Pistello1

1Virologia AOUP; 2UO Malattie Infettive AOU Pisa, 3SOD Chirurgia Proctologica e Perineale AOUP, 4UO Anatomia Patologica 1 AOUP, 5ORL 1 Universitaria AOUP, 6UO Urologia Universitaria AOUP, 7SOD Microbiologia batteriologica AOUP, 8UOC Igiene e Sanità Pubblica Azienda USL Toscana Nord Ovest

Abstract
Abstract
Poster
Poster
Audio
Audio

P 189HIV and STIs amongst MSM in Italy: data from the EMIS 2017 survey

M. Cordioli1, L. Gios1, M.L. Cosmaro2, M. Breveglieri3, F.M. Nimbi4, G.M. Corbelli5, N. Sherriff6, M. Mirandola1,6

1UOC di Malattie Infettive e Tropicali, Dipartimento di Diagnostica e Sanità Pubblica, Università di Verona / Infectious Diseases Section, Diagnostics and Public Health Department, University of Verona, 2Fondazione Lega Italiana per la Lotta contro l’AIDS – LILA Milano, 3Arcigay, 4Dept of Dynamic and Clinical Psychology, Sapienza University of Rome, 5Plus Network persone LGBT sieropositive, 6School of Health Sciences, University of Brighton, Brighton, UK

Abstract
Abstract
Poster
Poster

P 190Never Infected. Perception of the Risk of HIV Infection in Case of Undetectable Virus

F. Corbisiero1, C. Urciuoli1, E. Zito1, M. Cotugno2, F. Borrelli2, G. Di Filippo2

1Dipartimento di Scienze Sociali dell’Università degli studi di Napoli Federico II, Naples, 2Unità Ospedaliera Complesse Malattie Infettive Azienda Ospedaliera Universitaria Federico II, Naples

Abstract
Abstract
Poster
Poster

P 191Linkage to care in HIV: the point of view of people with recent diagnosis

P. Piselli1, C. Cimaglia1, L. Rancilio2, P. Meli3, M. Farinella4, E. Teti5, V. Calvino6, G.M. Corbelli7, M. Stagnitta8, M. Errico9, F. von Schloesser10, M. Breveglieri11, A. Caraglia12, M. Oldrini13, E. Girardi1 for the project “Linkage to Care in HIV: a further piece to the analysis of continuum of care in HIV in Italy”

1INMI “L. Spallanzani” IRCCS, Rome, 2Caritas Ambrosiana, Milan, 3CICA, 4Circolo Mario Mieli, Rome, 5Fondazione Villa Maraini, Rome; 6 Anlaids, 7PLUS, rete persone LGBT+ sieropositive, 8CNCA, 9NPS Italia, 10Nadir, 11Arcigay, 12Minister of Health, 13LILA, Milan

Abstract
Abstract
Poster
Poster

P 192AIDS and other sexually transmitted diseases: what do young people know? - a Cross Sectional Study

S. Francescon, L. Pisano, A. Zanovello, F. Lacarbonara, D. Gregori, M. Martinato

Servizio Clinical Trials e Biometria - Università degli Studi di Padova, Padova PD

Abstract
Abstract
Poster
Poster

P 193Prevalence and risk factors associated with new diagnosis of STI in individuals attending an in-hospital STI clinic

G. Mulé, D. Tesoro, L. Gazzola, A. Tavelli, G. Ancona, S. Cianciola, P. Tonietti, K. Reister, R. Castoldi, M. Allegrini, A. De Bona, A. d'Arminio Monforte

Department of Health Science, Clinic of Infectious Diseases, ASST Santi Paolo e Carlo, University of Milan, Italy

Abstract
Abstract
Poster
Poster
Audio
Audio

P 194SRHR Sensitization and Education activities from Medical Students

E. Clemente, M. Garbarini

Anlaids, Milan; Fondazione The Bridge, Milan; HIV Coalition, Milan

Abstract
Abstract
Poster
Poster

P 195"Senza la C" - HCV diagnosis and treatment for people who inject drugs in a community-based setting: results from an experience in Bologna

B. Granozzi2, L. Badia2, D. Testi2, E. Rosselli Del Turco2, V. Guardigni2, G.M. Corbelli1, S. Mattioli1, G. Verucchi2, P. Viale2, S. Pieralli3

1Plus onlus, Bologna, 2Policlinico S. Orsola-Malpighi - Dipartimento di Malattie infettive, Bologna, 3Open Group, Bologna

Abstract
Abstract
Poster
Poster

P 196WE TEST - National community-based HIV prevention program

R. Dartenuc1, D. Zagato2

1ARCO - Associazione Ricreativa Circoli Omosessuali, 2ASA - Associazione Solidarietà AIDS Milano

Abstract
Abstract
Poster
Poster

Poster: Vaccines

P 197Anti-body response to pneumococcical vaccination in HIV patient after supplementation with probiotic

M. Pontolillo, A. Auricchio, L. Caiazzo, A. Brandimarte, K. Falasca, C. Ucciferri, F. Vignale, J. Vecchiet

Clinic of Infectious Diseases, “G. d’Annunzio” University Chieti-Pescara, Chieti, Italy

Abstract
Abstract
Poster
Poster
Audio
Audio

P 198Adherence to the influenza vaccination campaign: experience of a large clinical center

D. Moschese1, A. Ciccullo1, A. Borghetti2, F. Lombardi1, A. Dusina1, C. Picarelli1, D. Farinacci1, A. D'Angelillo1, E. Visconti1,2, E. Tamburrini1,2, S. Di Giambenedetto1,2

1Sezione di Malattie Infettive - Dipartimento di Sicurezza e Bioetica - Università Cattolica del Sacro Cuore, Roma, Italia, 2UOC di Malattie Infettive - Fondazione Policlinico Universitario "Agostino Gemelli" IRCCS, Roma, Italia

Abstract
Abstract
Poster
Poster

P 199HPV oral infection and clearance in Men who have Sex with Men and Transgender Women undergoing nonavalent vaccination: preliminary results from an interventional study

R. Rossotti1, A. Nava2, M.C. Moioli1, C. Baiguera1, D. Fanti2, M. Merli1, M. Cernuschi2, L. Colagrossi2, S. Bossolasco3, A. Tamburini4, C.F. Perno2,5, M. Puoti1

1Department of Infectious Diseases, ASST Grande Ospedale Metropolitano Niguarda, Milan, 2Chemical-Clinical and Microbiological Analysis, ASST Grande Ospedale Metropolitano Niguarda, Milan, 3Infectious Diseases, IRCCS San Raffaele Scientific Institute, Milan, 4Gastrointestinal Surgery, IRCCS San Raffaele Scientific Institute, Milan, 5Department of Oncology and Hemato-Oncology, Università degli Studi di Milano, Milan

Abstract
Abstract
Poster
Poster

P 200Immunization status in a pediatric transplanted cohort: the Federico II teaching hospital experience

C. Resnati1,2, F. Di Dato3, F. Manco1, R. Iorio3, M. Cataldi1

1Dipartimento di Neuroscienze, Scienze Riproduttive ed Odontostomatologiche, Università degli Studi di Napoli Federico II, Napoli, 2Scuola di Specializzazione in Farmacologia e Tossicologia Clinica; Università degli Studi della Campania “L. Vanvitelli”, Napoli, 3Dipartimento di Scienze Mediche Traslazionali, Sezione di Pediatria, Università degli Studi di Napoli Federico II, Napoli

Abstract
Abstract
Poster
Poster
Audio
Audio

P 201Vaccination knowledge, attitudes and practices in patients with HIV: a cross-sectional survey

G. Orofino1, C. Alcantarini2, F. Bert4, E. Boietti3, A. Corradi3, M. Farenga1, M.R. Gualano1, S. Rousset1, S. Carosella1, M. Guastavigna1, M.C. Tettoni2, G. Voglino3, R. Siliquini3

1Division A of Infectious Diseases, Amedeo di Savoia Hospital, Turin, Italy, 2Unit of Infectious Diseases, Department of Medical Sciences, University of Turin, Turin, Italy, 3Department of Public Health Sciences, University of Turin, Turin, Italy, 4Molinette Hospital, City of Health and Science of Turin, Turin, Italy

Abstract
Abstract
Poster
Poster

P 202Success rate and evolution of immunological parameter over first vaccination against HBV with Fendrix© in People Living with HIV

C. Davoli, M. Mazzitelli, G. Greco, F. Serapide, P. Fusco, V. La Gamba, R. Lionello, V. Scaglione, C. Costa, V. Pisani, E.M. Trecarichi, C. Torti

Infectious and Tropical Disease Unit, “Magna Graecia University”, Catanzaro, Italy

Abstract
Abstract
Poster
Poster

P 203Organization of a dedicated vaccination service for HIV-positive patients, Pre-Exposure Prophylaxis (PrEP) users, and patients in care for sexually transmitted infections (STIs): the experience of S.M.Annunziata Hospital, Florence

E. Salomoni1, P. Zagli2, F. Vichi1, A. Degli Esposti1, P. Pierotti1, F. Baragli1, S. Esperti1, P. Blanc1

1S.O.C. Malattie Infettive 1, Ospedale Santa Maria Annunziata, Firenze - Azienda USL Toscana Centro, 2U.O. Assistenza Sanitaria, Dipartimento della Prevenzione - Azienda USL Toscana Centro

Abstract
Abstract
Poster
Poster

 
  • Poster Area
     

    Antiretroviral Therapy

    Chairs: R. Maserati, P. Nasta

    188Evaluation of total HIV-DNA and residual viremia in HIV-1 infected patients who continue a two-drug regimen with dolutegravir plus one reverse transcriptase inhibitor or switch to elvitegravir/cobicistat/emtricitabine/tenofovir alafenamide enrolled in the Be-OnE Study
    M. Santoro,
    268Durability and liver safety of InSTI-based regimens in HIV-infected patients with advanced liver fibrosis or cirrhosis: data from the ODOACRE cohort
    A. Lanari,
    281Prevalence of transmitted resistance mutations to rilpivirine and doravirine in treatment-naive patients in a large clinical and resistance database
    F. Lombardi,
    117Efficacy and tolerability of bictegravir/ tenofovir alafenamide/ emtricitabine as a switch strategy in a cohort of antiretroviral therapy treatment-experienced HIV-1-infected patients
    F. Lagi,
    163Viral rebound in pts with suppressed HIV-RNA on a 2 or 3-drug regimen: a comparison
    A. Borghetti,
    191Optically traceable PLGA Nanoparticles improve the ability of darunavir to cross the blood brain barrier and inhibit MMP-9. Implications for the Treatment of HIV-Associated Neurological Disorders
    S. Milella,
    199Effectiveness and long-term durability of rilpivirine-based single tablet regimens in a large cohort of HIV-infected patients. A preliminary analysis
    R. Pincino,
    5Increase in body weight after a year of INI-exposure in a multicenter italian cohort
    A. Ciccullo,
    226Treatment outcome among HIV-1 infected patients who started first-line ART pending GRT results from 2015 to 2018
    D.F. Bavaro,
    92Retrospective analysis of reasons and characteristics of switches in a cohort of women affected by HIV infection referring to D. Cotugno Hospital, Naples, period 2017-2019
    F.M. Fusco,
    217Assessing the feasibility of 2-drug regimens as switch strategies in a multicenter cohort
    A. Ciccullo,
    95Risk of failure in dual vs triple therapy in naïve HIV-patients: a meta-analysis
    A. Russo,

    Basic Science and Immunology

    Chairs: L. Butini, S. Piconi

    309DAA treatment fails to restore the inflammatory profile both in HCV/HIV and in HCV infected patients
    C. Agrati,
    79Sterol metabolism modulates susceptibility to HIV-1 Infection
    I. Saulle,
    270Different amounts of activated or exhausted effector memory T cells among differentiated CD4+ or CD8+ T lymphocytes during primary, acute HIV infection
    A. Cossarizza,
    277HIV+ patients: modulating effects of antiretroviral therapy on cytokines' profile and microbiota composition
    G. Nannini,
    352Association between subclinical atherosclerosis and IFN-I response in HIV-1 infected patients
    G. De Girolamo,
    263p53/mir34a/SIRT1 loop and immune reconstitution relationship during chronic HIV infection
    V. Bordoni,
    19Lower Immune Activation in Perinatally than in Horizontally HIV-Infected Adults
    L. Taramasso,
    151Microbiota Composition in HIV-Positive and HIV-Exposed Uninfected Pediatric Subjects
    S. Cannizzo,
    18Switching to integrase inhibitors is not linked to weight increase in young adults and adolescents perinatally infected with HIV, results from a 10-years observational study
    L. Taramasso,
    143An atypical case of HIV-1 elite controller: 15 years of follow up
    C. Fimiani,

    Clinical HIV

    Chairs: M. Borderi, A. Ruggieri

    276Newly diagnosed HIV infected patients in Brescia, Northern Italy: epidemiological and clinical characteristics and possible targets of prevention and early diagnosis campaign
    G. Zuglian,
    16Rosuvastatin decreases serum inflammatory markers and slows atherosclerosis progression rate in HIV-infected patients with metabolic syndrome
    L. Calza,
    275Durability of InSTI-based regimen in geriatric people living with HIV. Data from the Italian Multicenter GEPPO Cohort
    E. Focà,
    206Weight gain and body composition changes in people living with HIV treated with Integrase Strand Transfer Inhibitors: a longitudinal assessment with Bioimpedance Vectorial Analysis
    M. Poliseno,
    189Transmitted drug resistance in newly diagnosed HIV-1-infected patients in a large teaching hospital of the Northern Italy
    L. Calza,
    28Same day treatment and rapid antiretroviral therapy introduction in a cohort of unselected newly-diagnosed HIV-positive individuals
    G. Lapadula,
    250Changes in homeostatic model assessment for insulin resistance (HOMA-IR) index in treated HIV-1 infected people on virological suppression
    C. Muccini,
    59A descriptive analysis on dual regimens' discontinuations in a multicentre Italian cohort
    D. Farinacci,
    346Virological response and resistance profile in highly treatment-experienced HIV-1 infected patients switching to dolutegravir plus boosted-darunavir in clinical practice
    D. Armenia,
    295Does rapid initiation of ART at HIV diagnosis impact on virological response and retention in care? A single center experience (Brescia, Northern Italy)
    N. Gregori,
    264Efficacy and durability of dolutegravir- or darunavir-based regimens in ART-naïve AIDS- or late-presenter patients
    M. Masini,
    259Efficacy Safety and Tolerability of the switch from efavirenz/emtricitabine/tenofovir disoproxil on alternate days or continuous treatment to bictegravir/emtricitabine/tenofovir alafenamide in virologically suppressed HIV+ (EBONY Study)
    M. Camici,

    Clinical HIV II

    Chairs: R. Bellagamba, V. Giacomet

    56Allogenic hematopoietic stem cell transplantation in HIV-positive recipients: a case series
    C. Oltolini,
    71Italian survey on clinicians' approach to Latent Tubercular Infection in people living with HIV
    L. Caiazzo,
    177A poor immunological recovery is associated with non-AIDS-defining cancers in the era of HAART: a case-control study
    A. Emiliozzi,
    216HPV infection in HIV+, MSM patients followed at a large HIV Clinic in Northern Italy
    E. Asperges,
    335Risk of multiple primary neoplasms and impact on survival of person living with HIV (PLWH)
    V. Mazzotta,
    68Development and standardization of a real time PCR for the quantification of HTLV-1 proviral load
    A. Primavera,
    35Is pretreatment HIV-1 integrase resistance increasing? A large Italian centre experience
    D. Canetti,
    252Association between low levels of HIV-1 DNA and HLA class I molecules in chronic HIV-1 infection
    C. Muccini,
    119Evolving epidemiology of HIV/AIDS in Campania Region, 2008-19: is HIV/AIDS population in Campania different?
    F.M. Fusco,
    324Impact of boosted vs unboosted antiretroviral regimen on Dolutegravir plasma and intracellular pharmacokinetics
    M. Ferrara,

    Comorbidities

    Chairs: F. Carli, P. Maggi, I. Maida

    51Inflammatory and neurometabolite changes among patients switching away from efavirenz and their correlation with neurotoxicity: results from the sub-study of a randomized controlled trial
    G. Lapadula,
    120Contribution of INSTI, BMI, physical activity or caloric intake to weight gain in PLWH
    G. Dolci,
    137Cerebrospinal Fluid CXCL13 as a marker of Intrathecal Immunoglobulin Synthesis and Immune-activation in treatment-naïve People Living with HIV
    M. Trunfio,
    287Evaluation of the association between cognitive performance and HAND diagnosis with the cognitive reserve in naïve HIV-infected patients
    A.C. Brita,
    234Are Low vitamin D plasma levels associated with intrathecal immuneactivation in PLWH?
    A. Vergori,
    175Gender differences in neurocognitive functions in PLWK
    V. Delle Donne,
    246Menopause in aging women living with HIV: changes in bone mineral density and trabecular bone score
    D. Morini,
    230NAFLD phenotype and prevalence across the menopause spectrum in women with HIV
    J. Milic,
    84Incidence of diabetes in a cohort of PLWH people living with HIV in Perugia
    E. Schiaroli,
    203Standard vs higher dose of Rifampicin in patients with tuberculosis: a meta-analysis
    V. Gentile,

    Hepatitis and Coinfections

    Chairs: O. Armignacco, M. Massari, C. Sagnelli

    179Rapid Detection of Mycobacterium tuberculosis DNA in pulmonary and extrapulmonary paraffinized samples by ddPCR
    M. Antonello,
    153Pharyngeal contamination is a major driver for sexually transmitted infections epidemic in Men who have Sex with Men
    R. Rossotti,
    97HCV infection in PWUD: a microelimination intervention in Rome
    C. Taibi,
    98Direct-acting antiviral based treatment for HCV-infected persons who inject drugs: a multi-centre real-life study
    L. Onorato,
    322Are Non-Injecting Drug Users at risk of HCV-infection? Data from the San Patrignano cohort
    A. Boschini,
    187Real Life DAAs in a large cohort of people who use drugs with hepatitis C virus infection in Tor Vergata Hospital in Rome: adherence, efficacy and reinfections of a key population
    T. Mulas,
    342Effects of HCV eradication on liver function in haemophilic HIV/HCV co-infected patients
    V. Castelli,
    248Virological patterns of HCV-patients with failure to second generation direct-acting antivirals
    M. Starace,
    47Advanced liver disease outcomes after Hepatitis C viral eradication according to Human Immunodeficiency Virus coinfection in PITER cohort
    M.G. Quaranta,
    312The combination of accurate serological and virological HBV markers can help to predict the occurrence of HBV reactivation and to optimize prophylaxis duration in HBsAg-negative/anti-HBc-positive patients with oncohematological diseases
    M. Alkhatib,
    134HBV and HDV infection in immigrants living in South Italy: epidemiological and virological characteristics
    L. Onorato,
    130HEV infection as an emergent public health issue: is it a concern for Italian blood donors?
    L. Colagrossi,

    Social Science and Prevention

    Chairs: S. Babudieri, B.M. Celesia, M.G. Di Benedetto

    104HIV SelfTesting: a survey of self-tests availability in Italian Pharmacies
    M. Maffeo,
    106Testing MSM in cruising venues
    D. Zagato,
    370Behavioral aspects of MSM tested in community-based settings in 5 cities
    M. Breveglieri,
    29Pre-exposure prophylaxis in Modena: a wide spread of sexually transmitted infections among users attending the dedicated outpatient Clinic
    C. Rogati,
    154Prevalence and risk factors for HPV anal infection in PrEP users: implications for vaccination policy
    R. Rossotti,
    112NEETagers for the prevention of HIV and AIDS
    V. Corallino,
    90Clinical research integrated with narrative medicine to understand living and coping with HIV: TMC114FD1HTX4011 - DIAMANTE study
    G.C. Orofino,
    292Women and HIV in prison setting: a data up date from the Italian ROSE network
    E. Rastrelli,
    166First-year experience of an HIV clinic-based stop-smoking service
    V. Spagnuolo,
    148Psychiatric disturbances are common in PrEP users: an analysis of comorbidities and comedications in real life
    R. Rossotti,

    Virology and Pharmacology

    Chairs: R. Cavallo, S. Parisi

    271The HIV-1 provirus excised by CRISPR/Cas9 may be integrated back into the cell genome in presence of the viral integrase
    M. Lai,
    192Analysis of HIV latency establishment and maintenance in CD4 T cells stimulated with IL-15
    L. Manganaro,
    76Phylogenetic analyses applied to the study of transmission variants and their evolution in a HIV-1 positive couple
    C. Fenizia,
    74Creation of an Italian HIV DNA Network for the validation and clinical use of HIV-1 DNA quantification assays
    I. Vicenti,
    63Initial characterization of elements detected and quantified exclusively on the basis of LTR region by Aptima HIV-1 Quant Dx dual-target assay in plasma of HIV-positive patients
    A. Amendola,
    208Stable total HIV-DNA after 1 year on switch to TAF-based regimens in real world data
    C. Alteri,
    165HIV-1 RNA and DNA mutational load in HTE patients with MDR virus: a tool for deciding OBR?
    D. Armenia,
    96Viral tropism does not have any impact on CD4 recovery in acute HIV infection or AIDS
    D. Vita,
    291Antiviral effect of HIV1 tat/rev siRNA carried by nanoparticles in human CD4+ T cell line
    F. Falasca,
    344A real-life experience of vaccination strategies for HBV prevention in HIV patients
    D. Tomasoni,
    235A successful experience of an immunization program in HIV-positive adults
    G. Chieffo,
    64Plasma exchange and dolutegravir exposure. A case report
    M. Mussa,

    Poster: Bacterial and fungal infections in immunocompromised host

    10A descriptive analysis of bloodstream infections in patients living with HIV in a large Italian center
    45Amebic abscess of the spleen with severe sepsis and bronchial fistulisation in HIV+patient: case report
    53Pneumocystis jirovecii Pneumonia in HIV-negative Patients, a Frequently Overlooked Problem: Case Series from a Large Italian Center
    111Infection by Mycobacterium chimaera in two subjected undergoing cardiac surgery
    156A case of persistent relapsing abdominal mycobacterial infection requiring prolonged intravenous multi-drug treatment

    Poster: Basics in viral hepatitis

    288Comparison of immunoassays for quantitative serum HBsAg
    330Cryptic HBV replication is frequently revealed in anti-HBc positive/HBsAg negative patients with HIV infection by applying a highly sensitive digital droplet PCR assay

    Poster: Cancers in HIV

    32The multidisciplinary group for HPV related disease and STD in Azienda Ospedaliera Universitaria Pisana (AOUP) Cisanello. An opportunity for HIV and HIV at risk people
    49Non-AIDS-defining cancers in a cohort of HIV positive patients
    116Case report on oncopathology in HIV-infected patients
    145Primitive NHL of bone in an HIV patient: case-report and review of literature
    253Alexithymia and cancer-related mortality in Human Immunodeficiency Virus-Infected Patients: An Italian Multisite Prospective Cohort Study
    320Oral Human Papillomavirus (HPV) detection in the context of the multidisciplinary HPV group in Azienda Ospedaliero-Universitaria Pisana (AOUP): a screening opportunity for HIV+ and other at risk-patients
    351HCC Recurrence 8 years post Liver-Transplant was linked to Hepatitis Delta Reactivation in a person living with HIV
    358Epidemiological analysis from a newly established anal HPV screening ambulatory

    Poster: Gender issues

    139Behavioural and awareness changes in a HIV prevention program based on women empowerment in Uganda
    204Therapy burdens of Italian women living with HIV - Findings from the Positive Perspectives 2 Study
    225Transgender people and HIV
    232HIV-positive transgender people in follow-up at an Italian single tertiary care hospital in Florence: a cross-sectional study
    365HPV and bacterial vaginal infection impact on immune system in a cohort of HIV female population under suppressive ART

    Poster: HCV elimination

    6Qualitative analysis of significant clinical events in a cohort of patients after DAA treatment for chronic HCV infection after virological eradication
    37A fast track city micro-project to eradicate HCV infection in PLWHIV
    43A pilot intervention for HCV elimination among MSM in Rome: preliminary results
    58HCV eradication in people living with HIV in Sassari: the final countdown?
    69Glecaprevir/Pibrentasvir and Sofosbuvir/Velpatasvir/Voxilaprevir failure in a young man with genotype 1a congenital HCV infection: a case presentation
    83Acute hepatitis C treatment with direct antiviral agents (DAAs) in patients with solid organ cancer
    100How to eliminate HCV in people who inject drugs? Preliminary results of a provincial multi-targeted approach involving three different settings: addictions services, prison, outreach mobile unit for active users
    124Innovative procedures for micro-elimination of HCV infection in persons who use drug (PWUD)
    132Short course therapy for chronic hepatitis C infection
    133DAA failure in HCV genotype 3: virological features and efficacy of re-treatment
    186Therapy of Hepatitis C in Prison: Experience of Systematic Treatment Program in Rome
    212Five years real-life experience with direct-acting antivirals for hepatitis C in a suburban setting in Rome: a retrospective analysis
    244Association Between Polymorphism in the Enhancer Gene and Hepatitis C Virus-induced Hepatocellular Cancer Risk
    285Genotyping and treatment issues with unusual 1e and 1g HCV subtypes from African subjects: report of two cases
    313Feasibility and impact of HCV treatment in a HRS in Milan
    338An effective strategy to achieve HCV micro-elimination: HCV test and treatment into two Harm Reduction Services in Milan
    350Long follow up of monocyte-macrophage immuneactivation markers in HCV mono-infected patients undergoing DAA treatment
    353EradichiamoCi: HCV micro-eradication project among 5 psychoactive substances user services using a DAA delivery strategy
    354Effect of direct antiviral therapy against HCV on CD4+ T cell count in patients with HIV-HCV coinfection
    357HCV treatment in PWID: a linkage to care model in Cagliari

    Poster: Hepatitis epidemiology

    142Hepatitis A: has the outbreak ended?
    193Re-treatment of HCV infection following failure to DAAs: data from the SCOLTA cohort
    215HEV in Southern Italy. Still a chimera?
    243Evaluation of early HCC occurrence rate and its risk factors in HCV patients treated with direct-acting antivirals

    Poster: HIV and COVID

    374Covid-19 in patients with HIV-1 infection: a single-centre experience in Northern Italy
    377A case of acute hepatitis C in a patient with HIV, occult HBV and SARS-CoV-2 co-infection
    380SARS-CoV-2 infection in a highly-experienced person living with HIV
    381SARS-CoV-2 infection in a HIV+ patient on darunavir-based ART monotherapy: a case report
    386COVID-19 in people living with HIV (PLWH): clinical picture, viral clearance, cellular and antibody response in a case series of a reference HIV/AIDS center in a COVID Hospital in Rome
    388Clinical course and viroimmunological impact of COVID-19 in HIV infected patients: a single-center report from Milan, Italy
    389Management of emergency COVID-19 in prison, Monza experience
    391Psychological impact and awareness of COVID-19 in young people with HIV
    393Review of lopinavir and darunavir use in SARS-CoV-2 and HIV co-infection: is it time to find another role and another actor?
    395Seroprevalence of SARS-CoV2 antibodies in paediatric HIV patients

    Poster: HIV and nervous system

    140Study of the types of the nervous system based on temperaments of HIV-infected patients
    141Persistent activation of CXCL13 axis in the Cerebrospinal fluid of People Living with HIV despite Central Nervous System Viral Suppression
    173Limited health literacy (HL) ability and low awareness of HL difficulties in people living with HIV
    178Evolution of cognitive performance at a 2 years follow-up in a group of HIV-infected patients
    260Cerebrospinal fluid viral replication and burden of resistance in HIV-1-infected people with multidrug resistance treated with Ibalizumab
    265In Vitro Effect of Efavirenz on Cultured Primary Astrocytes: Analysis of Neurotoxicity and Matrix Metalloproteinase Inhibition
    286Evaluation of Patient-Reported Outcomes (PROs) and cognitive performance in HIV naïve patients with advanced disease: results from the PRO-Advance study
    302Cerebrospinal Fluid anti-EBV Viral Capsid Antigen IgG Production associates with poorer Performance in Attention, Memory and Executive functions domains among People living with HIV
    304Cryptococcal meningitis in a young woman HIV late presenter: a case report

    Poster: HIV cure

    183A multidisciplinary approach to imprint a successful long term adherence skill to Antiretroviral Therapy in naive patients: background and preliminary data of a pilot project of the GLAD group
    329Switching Dolutegravir/Abacavir/Lamivudine single tablet regimen (STR) to a less-costly multi-tablet regimen of Dolutegravir+Abacavir/Lamivudine (generic) in the setting of virologic suppression: data at 48 weeks
    336Complementary-alternative medicines and self prescribed drugs use in women living with HIV

    Poster: HIV epidemiology and retention in care

    44Availability of rapid HIV self-test in Italian pharmacies: a survey
    72REducing LAte Presenters Patients rate in Milan area (RELAPP Study): preliminary results
    81May administering routine HIV test be useful to uncover the iceberg in a University Hospital setting? Our experience
    87High rates of lost-to-follow-up among naive HIV+ female population: real-life data from UOC "Immunodeficienze e Malattie Infettive di Genere", D. Cotugno Hospital, Naples, 2017-19
    149Risk Factors for Late HIV Presentation in a Tertiary Care University Hospital
    157Epidemiology and clinical characteristics of HIV/AIDS among foreign in Campania Region, 2008-19: which differences with Italian population?
    196The efficacy of cART regimens and retention in care in an HIV-infected cohort of naïve patients
    205Characterization of HIV-1 transmission dynamics in North and Central Italy over the years 2012-2019
    224"EXTERNA": QoL Perception in PLWHIV during ID checkup
    233HIV screening in migrant population living in "ghetti" in Apulia
    254Geographic distribution of delayed presentation of HIV infection in HIV Emilia Romagna Surveillance System
    274Immunological evolution of a cohort of HIV-2 infected patients: peculiarities of an underestimated infection
    305HIV testing offer and services to improve linkage to Care in public services for HIV test: a survey
    333Gap in care and loss to follow up due to administrative barriers among migrants living with HIV in the city of Padova
    359Long-term survivors in a cohort of HIV+ patients diagnosed between 1985 and 1994: predictive factors associated with more than 25 years of survival
    371New diagnoses of HIV infection: what has changed in 10 years

    Poster: HIV immunology and immune-based therapies

    91Acne vulgaris as possible Immune Recovery Folliculitis driven by the lymphocyte T CD8+ immunological recovery in naïve and experienced patients
    240Influence of HLA haplotype on immunological recovery in HIV-infected patients

    Poster: HIV pathogenesis

    366Oxidative Stress and gut microbiota composition in primary HIV infection

    Poster: HIV prevention (PrEP and PEP)

    4PrEP awareness and attitudes in a survey among Italianclinicians
    14PrEP: the stories about who used the therapy
    21Young People Inform Young People - Speak to the students with the Peer Section of the School Project
    46Problems and difficulties in the management of a PrEP clinic
    52Post-exposure prophylaxis in real life
    146Determinants of drug start, schedule change and discontinuation in PrEP users
    147No increased risk of adverse events and sexually transmitted infections in PrEP users despite the rise in condomless sex
    159PreP: psychological and emotional aspects
    168PrEP use amongst MSM in Italy: data from the EMIS 2017 survey
    181Pre-Exposure Prophylaxis (PrEP): the one-year experience of the first dedicated service of Tuscany Region in S.M.Annunziata Hospital, Florence
    239In vitro effect of Castanea Sativa Mill. bark extract (ENC®) on HIV-1 infection: a potential microbicide

    Poster: HIV virology

    158Undetectable versus low level HIV viremia on patients taking antiretroviral therapy
    169Quantification of total HIV-1 DNA in the peripheral blood of naïve and treated patients
    174HIV2-Vpx modulation of MDDCs-CD4+ T cells HIV-1 Trans Infection
    184New potential anti-HIV agents: the antimicrobial peptide Temporin L
    194Fast and sensitive qPCR assay for the concomitant quantification of bacterial 16S rDNA and HIV-1 DNA: preliminary data from blood samples of HIV-1 infected patients
    273HIV-DNA quantification in PBMC: evaluation of two new real-time PCR commercial test
    315Influence of HIV-1 V2 domain characteristics on immunological recovery under ART
    318Susceptibility to HIV-1 integrase inhibitors in HIV-1 sub-subtype A6 isolates
    319Residual phenotypic susceptibility to second generation NNRTI in multidrug resistant HIV-1 from the PRESTIGIO Registry
    325In vitro activity of Islatravir against HIV-1 mutants harboring multiple NRTI resistance mutations
    332Does HLA-C binding stability affect HIV-1 infection?
    373Genotipic Resistance test in rapid ART era

    Poster: HIV-associated tuberculosis

    210Tuberculous and non tuberculous mycobacterial extra-pulmonary infections in HIV

    Poster: Issues on antiretroviral therapy

    9Short-Cycle Therapy comprising a lamivudine and dolutegravir regimen of 5 days on and 2 off in a small cohort of suppressed HIV-infected patients
    89Are 2-drug regimens with lamivudine plus boosted-PI still a feasible option in the era of integrase inhibitors? A multicenter analysis
    102HIV-DNA decay in ART-naïve patients starting a DTG-based dual vs triple therapy
    115Side effects detected in HIV-positive patients depending on the ART regimen
    118Safety and tolerability of tenofovir alafenamide (TAF) on bone mineralization and renal function in a cohort of young adults with HIV infection
    129A rare case of acute tubular necrosis tenofovir alafenamide-related
    152New cases of diabetes dolutegravir-associated in HIV patients: a case series
    170Reduced Bone catabolism and inflammation in patients switching to TAF-containing cART
    195Viral outcome on tailored treatment strategyusing cost saving antiretroviral (ARV)
    200The need for reducing both ARV and medicine-taking burdens among Italian PLHIV - Findings from the Positive Perspectives 2 Study
    214Switch to darunavir/cobicistat/emtricitabine/tenofovir alafenamide in HIV-infected patients not receiving protease inhibitors-based regimens
    220Nevirapine-based therapy in the twenty-first century: still an effective and safe long-term choice
    222Switch to dual therapy (3tc+dtg or rpv+dtg) in a cohort of people living with HIV: experience from real life
    245Changes in lipid profile and subclinical atherosclerosis after switching to tenofovir alafenamide (TAF) containing antiretroviral regimens in people living with HIV
    258An early proactive switch to elvitegravir/cobicistat/emtricitabine/tenofovir alafenamide (E/C/T/TAF) is effective in maintaining virologic control, reducing low level viral replication and continuing immunological recovery in patients with a primary HIV-1 infection (PHI). An interim analysis of a phase IV clinical trial (ESTER study)
    284Efficacy of dolutegravir versus darunavir in first-line regimens according to resistance mutations and viral subtype
    289Switch to dolutegravir-based dual therapy: outcomes in ART-experienced patients
    301Evaluation of efficacy and durability of raltegravir once-daily: real-life data from an Italian Center
    314Impact on CD4 count and CD4/CD8 ratio of 3 different integrase inhibitor-based regimens in naïve and experienced patients
    323Alteration of serum lipid profiles in HIV/HCV co-infected patients under treatment with HAART/DAAs combined therapy
    337Plasma viral load decay in first-time INSTI-users. A comparison between raltegravir, elvitegravir/cobicistat and dolutegravir
    339Metabolic profile changes after switching from a PI- to an INI-based regimen in the maintenance treatment of HIV infection
    361Evaluation of lipid profile in HIV naive patients, treated by TAF-based regimens

    Poster: Management and treatment of viral hepatitis

    23Younger Age, Male Gender and HCC presence are Associated to anti HCV-DAA failure
    48Reactivation of occult HBV infection in HIV patients treated with direct-acting antivirals for chronic hepatitis C: a retrospective study
    73DAA failure in HCV genotype not 1: virological features and efficacy of re-treatment
    78Virological features and efficacy of re-treatment in HCV patients: a real experience in Southern Italy
    94Overall survival at 3, 5 and 10 years of HIV-positive patients who underwent liver transplantation at the University Hospital of Ancona
    218Viro-immunological and histological characterization of a case of HBV-related hepatitis with immune reconstitution inflammatory syndrome after treatment initiation for HBV/HIV-1 co-infection with bictegravir/emtricitabine/tenofovir alafenamide
    363Indirect hyperbilirubinemia and jaundice during chronic hepatitis C in an HIV-infected patient treated with glecaprevir/pibrentasvir (GLE/PIB) and antiretroviral therapy (ART). The first reported case in Italy
    364Current management of hepatitis B in sclerosis patients treated with disease-modify therapies

    Poster: Management of HIV infection

    11Effect of 12-week physical activity program on sarcopenia measures in people living with HIV
    85Reasons for starting D/C/F/TAF and characteristics of patients enrolled in an Italian non-interventional study: the DIAMANTE (TMC114FD1HTX4011) study
    135HIV-1 DNA quantification: Comparative analysis and validation of two commercial qPCR assays
    227Intestinal Alkaline Phosphatase levels in HIV infected patients
    321Diagnostic performance of different screening strategies for the prevention of HPV-related anal cancer
    372Syphilis in newly HIV-1 diagnosed from 2010 to 2019: a single center report

    Poster: Non infectious comorbidities in HIV

    33TC+DTG versus FTC/TAF plus an integrase inhibitor: comparing changes in bone mineral density
    8HTA analysis of glatiramer and neuroprotection in HIV-related comorbidities
    15Low Vitamin D concentration is associated with NAFLD and metabolic syndrome in HIV-1-infected patients on combination antiretroviral therapy
    50Cardiovascular disease risk markers in a small cohort of HIV-infetcted patietns switched from abacavir/lamivudine/dolutegravir to lamivudine plus dolutegravir
    65Prevalence and incidence of Hepatic Steatosis in SCOLTA cohort
    101Factors associated with immunosenescence during early adulthood in HIV-infected patients after durable efficient cART
    138Metabolic changes in HIV-infected patients who continue a two-drug regimen with dolutegravir plus one reverse transcriptase inhibitor or switch to elvitegravir/cobicistat/emtricitabine/tenofovir alafenamide: a randomized study (Be-OnE Study)
    185A structured smoking cessation intervention in a single centre in patients living with HIV
    219Physical activity levels in HIV+ cohort of Pavia
    247Machine learning vs Knowledge based approach in health outcomes' prediction in HIV
    249Use of two drugs regimens (2DR) in a cohort of HIV-infected geriatric patients (GEPPO cohort)
    278Poor concordance between liver stiffness and non-invasive fibrosis scores in HIV-1 monoinfected virologically suppressed patients
    290Obesity and overweight among people living with HIV in the province of Pavia: a cross-sectional study
    347Evaluation of resting energy expenditure and body mass composition in a cohort of HIV infected patients on antiretroviral treatment
    367Archi-Prevaleat project. A National Register of color-Doppler ultrasonography of the epi-aortic vessels in Patients Living with HIV

    Poster: Pediatric, adolescent, maternal, fetal aspects

    201Rethinking the necessity of intrapartum zidovudine administration. A small case series from a single centre in the north of Italy

    Poster: Pharmacology, pharmacogenomics and drug interactions

    123Antiviral activity of 1-(41-chlorophenyl)-4-(42-methylphenyl)-5,6,7,8-tetrahydro-2a,4a-diazacyclopenta[cd]azulene-2-carboxylic acid derivatives
    136Antiviral activity of of 6-(4-methylbenzyl)-3-arylamino-4н-[1,2,4]triazin-5-оne derivatives against yellow fever
    360Dolutegravir, emtricitabine/tenofovir alafenamide fumarate absorption in a gastrectomized HIV-positive patient

    Poster: Social and behavioural science, marginalized groups, community aspects and community surveys

    7A survey as a chance of education on U=U in Italian general population
    12Development and management of a web-based system able to collect and analyse data about self-diagnostics HIV test - ULISSE
    13HIV prescriptivetrend 2018 vs 2019 in a teaching hospital in Rome
    24HAARTisticamente An unusual fashion show
    33"La prevenzione va in tournèe" a social experiment and on the field experience on HIV/STIs and social integration
    34Mono-symptomatic therapeutical group for Chemsex users - an ongoing experience
    41HIV rapid testing outside healthcare facilities: diagnostic and educational tool
    60Changes in causes of death of people living with HIV in a large teaching hospital in Rome
    70The PLWH perception of long acting injectable therapy
    82Cohort observational study and HIV brochure in a teaching hospital in Rome
    105HIV Self-Testing in Italy: a usability survey of clients using self-tests at two community organisations
    108Counselling and HIV rapid test for marginalized groups: data from an Emilia-Romagna Region project*
    110School and HIV. Cognitive and Emotional aspects for effective communication
    113Sardinia, first ever institutional Hiv testing and TasP promotion campaign: the communication strategy of Lila Cagliari team
    114"TEST WITH THE STAR": a pre-counselling "dog assistance" pilot project during HIV-HCV screening campaign "1st December World AIDS Day. Communities make the difference. Union makes the difference! HIV LATINA CHALLENGE 2019. U = U"
    160Test, condom and chems: how the habits of people in Milan change. A test experience in a premise
    167Coming out surrealista
    207App as tool for Prevention among students: the launch of a new counselling service about HIV/STIs promoted by Anlaids Onlus
    209PrEP between desire and needing: 2020 update
    237Free anonymous HIV Testing and linkage to care activities: data from the Milano Check Point
    242Pleasure and sociality as drivers of chemsex among Italian gay men living with HIV
    279The multidisciplinary (MD) HPV group in Azienda Ospedaliera Universitaria Pisana (AOUP). Impact of HIV-HPV sinergy. Preliminary data analysis
    282HIV and STIs amongst MSM in Italy: data from the EMIS 2017 survey
    294Never Infected. Perception of the Risk of HIV Infection in Case of Undetectable Virus
    297Linkage to care in HIV: the point of view of people with recent diagnosis
    303AIDS and other sexually transmitted diseases: what do young people know? - a Cross Sectional Study
    343Prevalence and risk factors associated with new diagnosis of STI in individuals attending an in-hospital STI clinic
    348SRHR Sensitization and Education activities from Medical Students
    356"Senza la C" - HCV diagnosis and treatment for people who inject drugs in a community-based setting: results from an experience in Bologna
    369WE TEST - National community-based HIV prevention program

    Poster: Vaccines

    55Anti-body response to pneumococcical vaccination in HIV patient after supplementation with probiotic
    144Adherence to the influenza vaccination campaign: experience of a large clinical center
    155HPV oral infection and clearance in Men who have Sex with Men and Transgender Women undergoing nonavalent vaccination: preliminary results from an interventional study
    161Immunization status in a pediatric transplanted cohort: the Federico II teaching hospital experience
    180Vaccination knowledge, attitudes and practices in patients with HIV: a cross-sectional survey
    190Success rate and evolution of immunological parameter over first vaccination against HBV with Fendrix© in People Living with HIV
    280Organization of a dedicated vaccination service for HIV-positive patients, Pre-Exposure Prophylaxis (PrEP) users, and patients in care for sexually transmitted infections (STIs): the experience of S.M.Annunziata Hospital, Florence

    Poster: Cancers in HIV

    261Kaposi Sarcoma among AIDS-presenters in Modena: could it be a cluster?
     
 
Plenary Room
Room 2
14.00 - 15.00
15.00 - 16.00

Pre-Conference advanced course

New frontiers in medical virology

Pre-Conference advanced course

New challenges in sexually transmitted infections: sexual health, prevention and more
 

Pre-Conference advanced course

Nurse management of patients with comorbidities
16.00 - 16.45

Satellite Symposium

Durable treatment success in HIV
16.45 - 18.30

Plenary Room

ICAR 2020 Opening Session

16.45 - 17.00: Introducing ICAR 2020 and Welcome Addresses

17.00 - 17.15: RaccontART HIV contest Awards

17.15 - 18.15: Keynote Lectures

18.15 - 18.30: Closing Remarks

 
  • Plenary Room
    14.00-15.00

    Pre-Conference advanced course

    New frontiers in medical virology

    Pre-Conference advanced course

    New frontiers in medical virology

    Infectious diseases are of public interest because of their impact on human, animal, and plant health. In this context, viruses play a central role in all aspects of medical research, ranging from molecular biology and immunology to evolution and epidemiology. The course will offer insight into the laboratory tools for the surveillance, diagnosis and monitoring of viral infections. It will also focus on novel aspects of viral pathogenesis and elaboration of therapeutic strategies.

    Chairs: I. Bon, B. Rossetti, C. Tincati

    14.00 - 14.10 Next-generation sequencing: a methodology changing the way to understand genome sequencing, evolution, ecology and discovery viruses
    N. Clementi
    14.10 - 14.20 Serological and molecular tools for detection of emerging viruses
    G. Rossini
    14.20 - 14.30 Role of HIV-1 protein variants in lymphoma pathogenesis
    F. Caccuri
    14.30 - 14.40 New frontiers of antiviral strategies
    O. Turriziani
    14.40 - 15.00 Discussion and conclusions
    15.00-16.00

    Pre-Conference advanced course

    New challenges in sexually transmitted infections: sexual health, prevention and more

    Pre-Conference advanced course

    New challenges in sexually transmitted infections: sexual health, prevention and more

    The consequences of sexually transmitted infections (STIs) on both individual and public health can be severe. The increasing incidence of STIs demands a call to action to ensure that populations at risk have access to comprehensive STIs prevention and care, especially in the context of expanded use of pre-exposure prophylaxis (PrEP) for HIV prevention. Integration of STIs services and PrEP is challenging but also provides a unique opportunity to optimize broader sexual and reproductive health services.

    Chairs: L. Badia, G. Cuomo, R. Rossotti

    15.00 - 15.10 Beyond PrEP: from a clinical management of STIs to a broader approach to sexual health
    M. Cordioli
    15.10 - 15.20 Test and Same Day Treatment in HIV: the role of screening and early ART initiation in the management of HIV
    A. Ciccullo
    15.20 - 15.30 Empowering people for their sexual health: how U=U changed the sexual lives of people living with HIV
    D. Calzavara
    15.30 - 15.40 Focus on vaccinations: are they an effective tool of sexual prevention?
    M. Digaetano
    15.40 - 16.00 Discussion and conclusions
    16.00-16.45

    Satellite Symposium

    Durable treatment success in HIV

    Con la sponsorizzazione non condizionante di:

    Satellite Symposium

    Durable treatment success in HIV

    Thanks to the advent of increasingly effective antiretroviral drugs and the additional knowledge/experience gained, HIV infection is now a manageable chronic condition, in which the achievement of immune-viral control has become a reality for the majority of treated patients. Therefore, it becomes essential to "update" the clinicians' and patients' perspectives of the disease, targeting not only the mere control of the virus (both at the population and patient level) but also the global health of current PLWHIV. This latter aspect becomes even more crucial since patients still are vulnerable due to a residual disease driven by non-AIDS defined comorbidities. Reflecting on current challenges and available strategies to fill these gaps will be essential, also with the support of real-life data. These themes will be addressed in an interactive way, through a direct dialogue between physicians and patients.

    Chair: C. Mussini

    16.30 - 16.45 Global Health in HIV
    S. Vella
    16.45 - 17.15 Round Table "Strategies for durable treatment success"
    Participants: M. Andreoni, G. Di Perri, A. d'Arminio Monforte, G.M. Corbelli
    16.45-18.30

    ICAR 2020 Opening Session

    16.45 - 17.00: Introducing ICAR 2020
    Welcome Addresses

    17.00 - 17.15: RaccontART HIV contest Awards

    17.15 - 18.15: Keynote Lectures

    18.15 - 18.30: Closing Remarks

    ICAR 2020 Opening Session

    16.45 - 17.00 Introducing ICAR 2020
    Chairs: M. Clementi, S. Mattioli, C. Mussini, G. Silvestri, M. Tavio
    17.00 - 17.15 RaccontART HIV contest Awards
    Chairs: A. Caraglia, M. Errico, A. Lazzarin
    17.15 - 18.15 Keynote Lectures
    Chairs: G.V. Calvino, A. Cossarizza, C.F. Perno, S. Vella
    17.15 - 17.35 Mauro Moroni Memorial Lecture "Immune control to reservoir: commencing countdown, control on"
    M. Paiardini
    17.35 - 17.55 Transgender, non-binary and HIV people: peculiarities of a key population between stigma and retaining in care
    O. Voza
    17.55 - 18.15 The public health response to new and future pandemics: lights and shadows from COVID-19
    G. Ippolito
    17.15 - 18.15 Closing Remarks
    Chairs: M. Clementi, S. Mattioli, C. Mussini, G. Silvestri, M. Tavio
  • Room 2
    15.00-16.00

    Pre-Conference advanced course

    Nurse management of patients with comorbidities

    Pre-Conference advanced course

    Nurse management of patients with comorbidities

    Achieving an undetectable viral load is no longer the sole endpoint in treating HIV. Today's challenge is to guide patients towards a proactive management of HIV-associated comorbidities.  Therapies have improved notably: nowadays patients diagnosed with HIV and treated with the latest antiretrovirals have a life expectancy comparable to the general population. A recent study showed that in 2010 patients' mean age was 43.9 years, whereas in 2030 is expected to be 56.6 years, with patients aged over 50 increasing from 28% to 73%.  Nonetheless, there are more challenges to face: aging with HIV puts patients to an increased risk of developing HIV-related illnesses, such as osteoporosis, hepatic, cardiovascular and neurological disease.  It is therefore necessary for the nursing staff to be to able to lead patients to a successful management of their comorbidities through a learning process based on efficient means of communication aimed at patients' empowerment.

    Chairs: E. Bruni, M. Gatti, S. Patrucco

    15.00 - 15.10 Cardiovascular risk factors
    M. Belli
    15.10 - 15.20 Nurse management of frail and elderly HIV-positive patients
    M. Gatti
    15.20 - 15.30 Therapeutic Patient Education in subjects with neurocognitive disorders
    S. Ondedei
    15.30 - 15.40 Nurse management of cancer patients
    A. Meda
    15.40 - 15.50 The nurse's role in managing the risk of infection in HIV-positive patients
    E. Bruni
    15.50 - 16.00 Discussion
 
Plenary Room
Room 2
Room 3
14.30 - 14.50

Plenary Room

Keynote Lecture
15.00 - 16.00
16.00 - 17.00

Symposium

Virus persistence and host interactions

Satellite Symposium

Fighting multi drug resistance - the right moment, the right drugs

Expert Meeting

Hepatitis C Elimination: the winning challenge of the 8-weeks treatment

Oral Communications

Social Science
 
17.00 - 17.20

Plenary Room

Keynote Lecture
17.30 - 18.30
18.30 - 19.30

Symposium

New metabolic challenges in comorbidities

Sponsored Symposium

Streamline ART from the start: the novel approach of 2DR single pill regimen dolutegravir/lamivudine

Oral Communications

Antiretroviral Therapy

Oral Communications

HIV Prevention
Meet the Expert
  • Antiretroviral therapy
  • Transgender
19.30 - 20.30

Plenary Room

ICAR-CROI Awards 2020 for young Italian HIV investigators
 
  • Plenary Room
    14.30-14.50 Keynote Lectures

    Keynote Lecture

    Chairs: M. Farinella, C. Mussini

    14.30 - 14.50 Visions of ART
    A. Pozniak
    15.00-15.55

    Symposium

    Virus persistence and host interactions

    Symposium

    Virus persistence and host interactions

    Antiretroviral therapy (ART) has gained a great deal of success in recent years and succeeded in suppressing viral replication in people infected with HIV. Nevertheless, infected cells persist for decades on ART and HIV-RNA comes back if ART is stopped. Persistence has been attributed to viral replication in cellular/anatomical reservoirs and long-lived and/or proliferating latently infected cells. This symposium aims at shedding light on the fine mechanisms of persistence of retroviruses and their cross-talk with the host immune system.

    Chairs: G. Antonelli, P. Bagnarelli, S. Rusconi

    15.00 - 15.10 Restriction factors and the peculiar function of CIITA
    R. Accolla
    15.10 - 15.20 The persistence of memory: HIV reservoir and adaptive immunity
    F.R. Simonetti
    15.20 - 15.30 Gene editing: from the virus side
    M. Pistello
    15.30 - 15.40 Gene editing: from the cell side
    R. Bella
    15.40 - 15.55 Discussion on Symposium issues
    16.00-17.00

    Satellite Symposium

    Fighting multi drug resistance - the right moment, the right drugs

    Satellite Symposium

    Fighting multi drug resistance - the right moment, the right drugs

    Patients with Multi Drug Resistant (MDR) HIV infection and few residual antiretroviral options are very likely to experience progression of the disease and death. To address this important unmet need, new antiretroviral agents are needed with novel mechanisms of action, good safety profile, no drug-drug interactions and no cross-resistance to other HIV drugs. The Symposium will focus on new modes of action currently in development and share latest clinical data conducted so far with ibalizumab, a new humanized IgG4 monoclonal antibody which blocks the entry of HIV by non-competitive binding to CD4. The Italian experience with the use of ibalizumab will also be presented.

    Chairs: C. Mussini, M. Zazzi

    16.00 - 16.05 Speaker's introduction and scientific rationale
    C. Mussini
    16.05 - 16.15 New treatments, new options
    A. Antinori
    16.15 - 16.25 Resistance to Long-Acting Antivirals
    M. Zazzi
    16.25 - 16.45 Building a fully suppressive regimen for patients with MDR - lessons learned
    B. Emu
    16.45 - 16.55 The Italian experience
    A. Castagna
    16.55 - 17.00 Discussion on Symposium issues
    17.00-17.20 Keynote Lectures

    Keynote Lecture

    Chairs: F. Ceccherini - Silberstein, A. De Rossi

    17.00 - 17.20 Genomics and proteomics approaches for studies of HIV eradication
    M. Lichterfeld
    17.30-18.25

    Symposium

    New metabolic challenges in comorbidities

    Symposium

    New metabolic challenges in comorbidities

    HIV ad cART comorbidities are continuously changing their presentations, in parallel with the evolving spectrum of antiretroviral treatment regimens and the demographic and clinical features of people with HIV (PWH). At present, the current scenario of metabolic comorbidities seems to reflect, on one hand, the extended use of potent antiretroviral drugs with a very high safety profile, and, on another hand, the increasing age of PWH and the persisting immune activation. This symposium discusses emerging issues in the field, including prevalence and impact of these complications and explore the potential of old and new tools for their definition and management.

    Chairs: A. Bandera, P. Bonfanti, F. Castelli

    17.30 - 17.40 The growing burden of nonalcoholic fatty liver disease in people aging with HIV
    G. Sebastiani
    17.40 - 17.50 Weight gain and new antiretrovirals: is a real issue?
    S. Cicalini
    17.50 - 18.00 Immune-metabolic interventions as geroprotective agents in HIV
    G. Guaraldi
    18.00 - 18.10 Artificial intelligence in aging: from data collection to data analitics
    C. Grana
    18.10 - 18.25 Discussion on Symposium issues
    18.30-19.30

    Sponsored Symposium

    Streamline ART from the start: the novel approach of 2DR single pill regimen dolutegravir/lamivudine

    Con il supporto di:

    Sponsored Symposium

    Streamline ART from the start: the novel approach of 2DR single pill regimen dolutegravir/lamivudine

    Remarkable advances in drug development for the treatment of HIV-1 infection have been achieved in recent years. From the co-formulation of combination antiretroviral therapy (cART) into single-tablet regimens to the development new antiretroviral drugs, the treatment of HIV has and will become much more tolerable and less complicated for people living with HIV (PLWH). Moreover, there is a focus on reducing short- and long-term toxicities of treatment while maintaining robust efficacy and good tolerability. In this scenario, one of the most recently options considered is 2-drug regimen (2DR) containing highly effective ARV compounds while excluding components that have relatively unfavorable toxicity profiles, with the potential additional advantage to minimize antiretroviral medication burden for improving effectiveness. In this novel therapeutic context, the 2DR consisting of the INSTI dolutegravir (DTG) and the NRTI lamivudine (3TC), represents today the unique regimen extensively studied versus standard 3- or 4-drug regimens both in naïve and virologically suppressed patients. Aim of the symposium is to highlight important considerations for the use of 2DR single tablet DTG/3TC in the context of existing and emerging ARV options.

    Chair: P. Rizzini

    18.30 - 18.45 The robustness of the evidences up to date: challenging the use of 3 drug regimens
    J.M. Gatell
    18.45 - 19.00 How dolutegravir/lamivudine meets the patient needs
    N. Nwokolo
    19.00 - 19.30 Discussion on Symposium issues
    19.30-20.30 ICAR-CROI Awards 2020 for young Italian HIV investigators
  • Room 2
    15.00-16.00

    Expert Meeting

    Hepatitis C Elimination: the winning challenge of the 8-weeks treatment

    Con la sponsorizzazione di:

    Expert Meeting

    Hepatitis C Elimination: the winning challenge of the 8-weeks treatment

    Thanks to the DAAs, the WHO's goal of HCV elimination by 2030 could be achieved more easily. The high efficacy of these antiviral drugs, characterized by great power, few DDIs and short treatment make the patient's journey less onerous and heavy. Clinical trials and RWE data demonstrate not only the high SVR rate of the short therapies but also the improvement of adherence to the treatment. This last aspect is fundamental for the special populations (PWIDs and patients from SERD) because the briefer the therapy, the less burdensome it is for them. The Expert Meeting will focus precisely of the opportunity of the short therapy in the challenge against HCV. In this context, it represents an important step towards the efforts for eliminating the hepatitis C because it evaluates a brief antiviral regimen in untreated patients without cirrhosis and with compensated cirrhosis, across HCV genotypes 1-6. Through a talk show session, the two Professors will explain and convey the main data and results of this HCV turning point to the audience. The latter will be able to intervene in the session thanks to an interactive platform that will allow the physicians to answer the questions formulated by the speakers.

    15.00 - 16.00 Hepatitis C Elimination: the winning challenge of the 8-weeks treatment
    M. Andreoni, M. Puoti
    16.00-17.00

    Oral Communications

    Social Science

    Oral Communications

    Social Science

    Chairs: G. Liuzzi, A. Matteelli, L.A.R. Rancilio

    16.00 - 16.10 OC 1Awareness and perception of accuracy of the U = U message in people living with HIV (PLWHIV), in Italy and correlation with the level of confidence in reference physicians
    A. Cingolani, Roma
    16.10 - 16.20 OC 2Hepatitis C, HIV and Tubercolosis among vulnerable populations in an out-of-hospital setting: a seroprevalence analysis from The week of the poor experience
    G. De Simone, Roma
    16.20 - 16.30 OC 3Engagement of younger generations in the fight against HIV/AIDS
    P. Meli, Bergamo
    16.30 - 16.40 OC 4Post-migration HIV infection in the foreign-born population enrolled in the ICONA cohort
    A. Saracino, Bari
    16.40 - 16.50 OC 5BLQ Checkpoint: characteristics of users and services offered. A 5 years review
    G.M. Corbelli, Roma
    16.50 - 17.00 OC 6Sexual behaviour and associated risk for sexual health among men who have sex with men (MSM) in Italy: data from the EMIS 2017 survey
    M. Breveglieri, Bologna
    17.30-18.30

    Oral Communications

    Antiretroviral Therapy

    Oral Communications

    Antiretroviral Therapy

    Chairs: M. Malena, C. Torti

    17.30 - 17.40 OC 7Durability of dolutegravir-based regimens after the first year of therapy
    L. Taramasso, Milano
    17.40 - 17.50 OC 8Switch to RPV+DRV/cobi: 48week results of the PROBE 2 study
    F. Maggiolo, Bergamo
    17.50 - 18.00 OC 9Predictors of virological failure among HIV-1 infected patients switching from an effective first line antiretroviral regimen. A preliminary analysis
    L. Magnasco, Genova
    18.00 - 18.10 OC 10Long term efficacy of dolutegravir + lamivudine as simplification cART in patients with suppressed HIV-RNA
    F. Maggiolo, Bergamo
    18.10 - 18.20 OC 11Lamivudine+dolutegravir (3TC+DTG) switch strategy compared with the single-tablet regimen of bictegravir/emtricitabine/tenofovir alafenamide (BIC/FTC/TAF) in virologically suppressed HIV patients: preliminary results from an Italian center
    G. Baldin, Olbia
    18.20 - 18.30 OC 12Durability of F/TAF regimens in the era of integrase inhibitors in a large cohort of PLWH seen for care in Italy
    A. Vergori, Roma
    18.30-19.30

    Oral Communications

    HIV Prevention

    Oral Communications

    HIV Prevention

    Chairs: A. Bignardi, T.S. Prestileo, B. Suligoi

    18.30 - 18.40 OC 13Engagement, adherence and rate of discontinuation in an Italian access program of HIV pre-exposure prophylaxis (ItaPrEP)
    V. Mazzotta, Roma
    18.40 - 18.50 OC 14Pre-Exposure Prophylaxis (PrEP) use at five Infectious Diseases Units in northern Italy (PrEP-Italy study)
    S. Venturelli, Bergamo
    18.50 - 19.00 OC 15Uptake and effects on sexual behaviour in a cohort of PrEP users
    P.L.G. Vinti, Milano
    19.00 - 19.10 OC 16Preventive measures against HIV and sexually transmitted infections among key populations referring to a counseling and testing center in the metropolitan area of Rome
    R. Esvan, Roma
    19.10 - 19.20 OC 17Incidence of STIs and HIV in a cohort of MSM and MtF with high prevalence of risk factors for HIV acquisition evaluated in a PrEP community-based service in Italy: one-year follow-up data from SEX-CHECK study
    D. Testi, Bologna
    19.20 - 19.30 OC 18HIV and motherhood - A survey on women's experiences in the U=U era
    M.G. Di Benedetto, Como
  • Room 3
    17.30-18.30

    Special event

    Meet the Expert

    Meet the Expert

    During these Sessions, participants will have the opportunity to informally discuss with top ICAR Experts and exchange with them personal views, receive practical insights about specific topics. Guided by Facilitators, these sessions represent an important opportunity for all delegates to sit down and converse on a more one-to-one level.

    Chairs: M. Cascio, S. Mattioli

    17.30 - 18.00 Antiretroviral therapy
    A. Pozniak
    18.00 - 18.30 Transgender
    O. Voza
 
Plenary Room
Room 2
Room 3
14.30 - 14.50

Plenary Room

Keynote Lecture
15.00 - 16.00
16.00 - 17.00

Sponsored Symposium

POP ART (population on ART): from patient to personas A new approach to fulfill PLHIV expectations

Symposium

Reaching out: same models for different infections

Oral Communications

Virology

Satellite Symposium

Recent advances in the management of Gram positive infections: the evolving role of long acting therapy
 
17.00 - 17.20

Plenary Room

Keynote Lecture
17.30 - 18.30
18.30 - 19.30

Satellite Symposium

Committed globally to fight HIV and other severe infections

Symposium

Lights and shadows in HIV clinical research

Oral Communications

Comorbidities

Oral Communications

Clinical Hepatitis and Coinfections
Meet the Expert
  • Chemsex
  • Drug-Drug Interactions
 
  • Plenary Room
    14.30-14.50 Keynote Lectures

    Keynote Lecture

    Chairs: S. Di Giambenedetto, F. von Schloesser

    14.30 - 14.50 Orientating in a maze. The Arianna's thread to partner notification
    M.L. Cosmaro
    15.00-16.00

    Sponsored Symposium

    POP ART (population on ART): from patient to personas A new approach to fulfill PLHIV expectations

    Con la sponsorizzazione di:

    Sponsored Symposium

    POP ART (population on ART): from patient to personas A new approach to fulfill PLHIV expectations

    The advent of the new antiretroviral drugs has permitted to obtain virological success in the majority of treated patients. This achievement has allowed the clinicians to focus on HRQoL (4th 90) to guarantee a long-term well-being. In this new context, populations defined by clinical conditions are now obsolete:  to achieve the 4th 90 goal we need to consider PLHIV lifestyles by moving from patient profile to personas concept. Each personas is different and has different expectations, therefore is crucial to contemplate all the key factors that contribute to obtain a better quality of life. In this evolving scenario, therapy still has a critical role in controlling the virus, but how can it fulfill doctors' and patients' needs to reach the HRQoL (4th 90)?

    Chairs: A. d'Arminio Monforte, C.F. Perno

    15.00 - 15.30 PLHIV in 2020: interactive discussion on personas
    C. Gervasoni, C. Madeddu, G. Madeddu
    15.30 - 15.45 How therapy can meet patients' needs
    S. Bonora
    15.45 - 16.00 Discussion on Symposium issues
    16.00-16.55

    Symposium

    Reaching out: same models for different infections

    Symposium

    Reaching out: same models for different infections

    The first of the United Nations' 90-90-90 targets to end the HIV epidemic is for 90% of people living with HIV to learn their HIV status. HIV testing is therefore essential to achieving the first 90. The only way to determine a person's HIV status is for them to have an HIV test. What is the best way? HIV testing in healthcare services is the traditional approach. Good results have been accomplished through it but there are some obstacles as  limited access and usability of the healthcare structures and the difficulty of people to undergo the test in the hospital. In recent years, the Point of Care (POC) have been successful to overcome some difficulties and to make easier the access to the test especially for populations who showed reluctance to go to the hospital. The European POC has also created a network to facilitate access to the hospital and to make access to care simpler and faster. It already has the result to accelerate the United Nations' 90-90-90 campaign . Discussing and finding further solutions requires reflection on the experiences that have been carried out by NGOs. Looking for concrete collaborations and new intervention strategies between POC and hospital can bring us closer to the WHO objectives and reinforce the equation Undetectable = Untransmittable (U=U) message. There is an opportunity to improve prevention, testing services and ensure high-quality well-adhered treatment and care for all.

    Chairs: S. Negri, V. Puro, E. Vaccher

    16.00 - 16.10 Amending missed opportunities for HIV testing in healthcare services
    S. Nozza
    16.10 - 16.20 Testing, prevention and treatment outside of the hospital: the checkpoint model
    G.M. Corbelli
    16.20 - 16.30 We are not hard to reach - Bringing people to the hospital and vice versa
    E. Teti
    16.40 - 16.55 Discussion on Symposium issues
    17.00-17.20 Keynote Lectures

    Keynote Lecture

    Chairs: M. Galli, E. Girardi

    17.00 - 17.20 New challenges in virology: SARS-CoV-2
    M.R. Capobianchi
    17.30-18.30

    Satellite Symposium

    Committed globally to fight HIV and other severe infections

    Con la sponsorizzazione non condizionante di:

    Satellite Symposium

    Committed globally to fight HIV and other severe infections

    Since the introduction of cART there has been increased survival in HIV-infected persons, so nowadays it is important to answer to individual HIV patients needs, going beyond viral suppression, as antiretroviral therapy is a life-long commitment. Furthermore, with the availability of two or three drugs combinations is becoming more crucial the physician's role in choosing and adapting the ART to treat population living with HIV (PLWH) avoiding issues about adherence, potential drug-drug interactions, long-term toxicities given that the PLWH is ageing with increasing comorbidities such as osteoporosis, renal, cardiovascular, metabolic and liver diseases, which need additional drugs. The aim of the symposium is to examine how current antiretroviral agents may be better incorporated into management strategies in daily practice to benefit patient's individuality now and to preserve the future. In this changing scenario, is interesting to show how the well-known NNRTI rilpivirine (RPV) has remained central to several key therapeutic innovations due to its proven durable efficacy & tolerability that delivers multiple benefits for HIV patients. Furthermore, while the global genetic diversity of HIV poses a considerable scientific challenge, the symposium will be an opportunity to discuss on the lnfectivologists & pharma company's commitment to HIV and other infections vaccine research, aiming to address these problems.

    Chair: C. Mussini

    17.30 - 17.45 Indhividuality: beyond viral suppression
    G. Madeddu
    17.45 - 18.00 The rilpivirine perspective: present and future
    S. Lo Caputo
    18.00 - 18.15 Back to basic: paving the way to HIV and other infections vaccines
    A. Castagna
    18.15 - 18.30 Discussion on Symposium issues
    18.30-19.25

    Symposium

    Lights and shadows in HIV clinical research

    Symposium

    Lights and shadows in HIV clinical research

    Evidence based medicine relies on well conducted clinical trials and comprehensive cohort data to draw its indications. However, no experimental design is completely free of drawbacks and limitations. Therefore, the results of different clinical experiences must be read in a critical way understanding which is the right field of application. The problem is further complicated in a constantly expanding field as HIV/AIDS by the need to adequate outcomes and measures to newly defined goals. The symposium will offer a comprehensive discussion about all these critical aspects of clinical management of HIV/AIDS.

    Chairs: P.M. Cinque, N. Gianotti, A. Gori

    18.30 - 18.40 What trials did not show
    F. Maggiolo
    18.40 - 18.50 What we cannot expect from clinical cohorts
    A. Cozzi-Lepri
    18.50 - 19.00 Innovative outcomes: what surrogate outcomes
    M. Santoro
    19.00 - 19.10 Unconventional innovative outcomes
    A. Cingolani
    19.10 - 19.25 Discussion on Symposium issues
  • Room 2
    15.00-16.00

    Oral Communications

    Virology

    Oral Communications

    Virology

    Chairs: S. Menzo, M.C. Re

    15.00 - 15.10 OC 19Defining stable reference genes to analyze cell associated HIV RNA induced by latency reversing agents
    C. Ceriani, Chapel Hill, USA
    15.10 - 15.20 OC 20Prevalence of drug resistance mutations to rilpivirine and doravirine among NNRTI -experienced patients in Italy: a cross-sectional study
    A. Lazzaro, Torino
    15.20 - 15.30 OC 21HIV-DNA from rectal GALT is a valid marker to characterize the viral reservoir
    C. Stingone, Roma
    15.30 - 15.40 OC 22Evaluation of HIV-1 tropism in multidrug-resistant cART failing patients
    Y. Bouba, Roma
    15.40 - 15.50 OC 23Does dual therapy have an impact on HIV-DNA decay in virologically-suppressed patients compared to triple therapy? Results from a multicentric study
    A. Emiliozzi, Siena
    15.50 - 16.00 OC 24Prevalence of high-risk HPV genotypes and HPV genotypes targeted by the nine-valent vaccine Gardasil-9 and the associated risk factors
    E. Bruzzesi, Modena
    16.00-17.00

    Satellite Symposium

    Recent advances in the management of Gram positive infections: the evolving role of long acting therapy

    Con la sponsorizzazione non condizionante di:

    Satellite Symposium

    Recent advances in the management of Gram positive infections: the evolving role of long acting therapy

    Gram positive infections are a continuing challenge for clinicians: while classic pathogens still persist and evolve acquiring new mechanisms of resistance, new pathogens emerge with intrinsic multiple antibiotics resistance profiles, causing life-threatening infections as nosocomial pneumonia and intravascular device associated bloodstream infections. Not less important, the population at risk, i.e. elderly with multiple comorbidities or recipients of various foreign bodies, is increasing. New therapy options are required, with increased bactericidal activity and antibacterial spectrum that includes multiple resistant pathogens. Recently, the antimicrobial armamentarium has been enriched by a lipoglycopeptide with a very prolonged half-life (dalbavancin) enabling treatment with a single intravenous administration.  Pharmacokinetic profile and convenient single dosing make dalbavancin an interesting option for other serious Gram positive infections requiring prolonged treatment courses, for example bone infections, endocarditis and intravascular line associated infections. The aim of this workshop is to focus on new pharmacological, clinical and pharmacoeconomical data with dalbavancin in order to provide an up-to-date of the actual and potential future role of this options for serious Gram positive infections.

    Chair: M. Tavio

    16.00 - 16.15 Gram+ subacute infections
    P. Viale
    16.15 - 16.30 The evolving role of long acting therapy in the management of Gram positive infections
    M. Andreoni
    16.30 - 16.45 Dalbavancin: pharmacokinetical data
    P. Viale
    16.45 - 17.00 Dalbavancin: pharmacoeconomical data
    M. Andreoni
    17.30-18.30

    Oral Communications

    Comorbidities

    Oral Communications

    Comorbidities

    Chairs: D. Francisci, G. Parruti

    17.30 - 17.40 OC 25Fat distribution and density in PLWH with >=5% weight gain
    M. Menozzi, Modena
    17.40 - 17.50 OC 26Statin Eligibility in People living with HIV: are we using the right tools to identify patients at risk of developing major cardiovascular disease?
    M. Mazzitelli, Catanzaro
    17.50 - 18.00 OC 27Prevalence, predictors and evolution of lean non-alcoholic fatty liver disease in HIV mono-infected patients
    A. Cervo, Palermo
    18.00 - 18.10 OC 28NAFLD with significant fibrosis in PLWH informs the natural history of cardiovascular disease
    J. Milic, Modena
    18.10 - 18.20 OC 29Decline of metabolic syndrome and increase in overweight in HIV infected patients from 2005-2015
    L. Taramasso, Milano
    18.20 - 18.30 OC 30Progression of anal/cervical dysplasia is associated with Human Papillomavirus (HPV) and Syphilis coinfection in HIV-infected patients
    C. Tincati, Milano
    18.30-19.30

    Oral Communications

    Clinical Hepatitis and Coinfections

    Oral Communications

    Clinical Hepatitis and Coinfections

    Chairs: G. Mazzola, T.A. Santantonio

    18.30 - 18.40 OC 31The contribution of late presentation and late ART initiation to TB-HIV occurrence across four countries
    E. Girardi, Roma
    18.40 - 18.50 OC 32HPV 16 and 18 infections contribute to development of anal cytological abnormalities in a cohort of PLWH
    N. Squillace, Monza
    18.50 - 19.00 OC 33Impact of syphilis on the risk of HIV viral rebound in HIV positive patients under effective antiretroviral treatment: data from the ICONA cohort
    A. Giacomelli, Milano
    19.00 - 19.10 OC 34Decrease of prevalence of subjects harboring replicating HCV among PLWHIV in Italy: results from the NoCo study
    A. d'Arminio Monforte, Milano
    19.10 - 19.20 OC 35Innovative procedures for micro-elimination of HCV infection in a high-risk population of undocumented migrants and low-income refugees
    M. Macera, Napoli
    19.20 - 19.30 OC 36HCV treatment and reinfection risk in injecting drug users in Residential Treatment Setting for drug addiction. San Patrignano HCV-free
    A. Boschini, Rimini
  • Room 3
    17.30-18.30

    Special event

    Meet the Expert

    Meet the Expert

    During these Sessions, participants will have the opportunity to informally discuss with top ICAR Experts and exchange with them personal views, receive practical insights about specific topics. Guided by Facilitators, these sessions represent an important opportunity for all delegates to sit down and converse on a more one-to-one level.

    Chairs: M. Breveglieri, S. Mattioli

    17.30 - 18.00 Chemsex
    C. Di Feliciantonio
    18.00 - 18.30 Drug-Drug Interactions
    D. Cattaneo
 
Plenary Room
Room 2
Room 3
14.30 - 15.15

Plenary Room

Round Table: HIV in COVID-19 era: how to ensure quality of care and outpatient management
15.20 - 16.20
16.20 - 17.20
17.20 - 18.20
18.20 - 19.20

Satellite Symposium

HIV: understanding the real burdens of the disease

Symposium

Immune control over HIV reservoir

Symposium

Challenges in PrEP implementation and TasP confidence

Symposium

HIV and Coinfections: new challenges for 2020

Oral Communications

Basic Science and Immunology

Expert Meeting

Enhancing care for people living with HIV: current and future of monitoring approaches

Oral Communications

Clinical HIV

Expert Meeting

Urgent global challenges in infectious diseases: fight together against HIV and AMR
 
Meet the Expert
  • Immunological update
  • Cure
 
  • Plenary Room
    14.30-15.15 Round Table: HIV in COVID-19 era: how to ensure quality of care and outpatient management

    Round Table

    HIV in COVID-19 era: how to ensure quality of care and outpatient management

    2020 has been so far very challenging for infectious disease specialists around the world especially for new coronavirus. The aim of the round table is to discuss how this emergency impacted on the outpatient management of HIV infected patients and, more generally, on their quality of care. Clinicians will talk about clinic experiences, recommendations and organizational models on management and security, diagnosis, screening, telemedicine while patients will relate about their perception on the quality of care with a focus on PrEP and STI management.

    Chairs: M. Andreoni, A.M. Cattelan

    Participants: M.G. Di Benedetto, M. Lichtner, S. Mattioli, S. Rusconi
    15.20-16.20

    Satellite Symposium

    HIV: understanding the real burdens of the disease

    Con il supporto incondizionato di:

    Satellite Symposium

    HIV: understanding the real burdens of the disease

    The today new standards of highly virologically effective antiretroviral regimens fully authorize clinicians to move the attention from pursuing viro-immunological outcomes, namely efficacy, to also considering in the clinical practice concrete strategies for preserving both quality of life and long-term well-being, namely effectiveness. Reducing all kind of medication burdens, both pharmacological and taking medicine ones, suggest a patient-centered approach.

    Chair: C. Mussini

    15.20 - 15.35 Reducing ARV and taking medicines burdens for improving effectiveness
    M. Andreoni
    15.35 - 15.50 The evaluation of patient complexity in the setting of ARV deprescribing
    G. Guaraldi
    15.50 - 16.15 Discussion on Symposium issues
    16.15 - 16.20 Closing remarks
    C. Mussini
    16.20-17.15

    Symposium

    Immune control over HIV reservoir

    Symposium

    Immune control over HIV reservoir

    Despite full control over HIV replication by cART, HIV has been shown to persist in lymphoid tissues, and represent a major obstacle to HIV eradication. The symposium will review the major immunologic pathways behind immune control over HIV, alongside the distinguishing features of patients with progressive versus non-progressive disease.

    Chairs: A. Caruso, M.S. Clerici, L. Sarmati

    16.20 - 16.30 Models of natural protection against HIV infection and progression
    M. Biasin
    16.30 - 16.40 Innate immunity: don't forget the macrophages!
    G. Poli
    16.40 - 16.50 Inflammatory stem cells
    A. De Maria
    16.50 - 17.00 Killing HIV by bNABs: apocalypse, now?
    L. Lopalco
    17.00 - 17.15 Discussion on Symposium issues
    17.20-18.15

    Symposium

    Challenges in PrEP implementation and TasP confidence

    Symposium

    Challenges in PrEP implementation and TasP confidence

    Pre-exposure prophylaxis (PreP) for HIV has proven effective in reducing the number of new infections in several trials and in different settings, while treatment as prevention (TasP) is one of the major advancements in the HIV field, becoming a major argument for supporting both the universal treatment and test and treatment strategies. However, issues are arising in PreP implementation in clinical practice, while the trust in TasP may be challenging when it comes to the real world, as both patients and clinicians may have different interpretations, expectations and confidence.

    Chairs: S. Maugeri, D. Ripamonti, L. Sighinolfi

    17.20 - 17.30 PrEParing providers
    S. Venturelli
    17.30 - 17.40 Challenges in becoming a PrEP user
    A. Infante
    17.40 - 17.50 How much trust in TasP?
    S. Venturelli
    17.50 - 18.00 Consequences of TasP
    A. Infante
    18.00 - 18.15 Discussion on Symposium issues
    18.20-19.25

    Symposium

    HIV and Coinfections: new challenges for 2020

    Symposium

    HIV and Coinfections: new challenges for 2020

    In the last years the control of HIV replication  obtained excellent results with more than 90% of patients being undetectable. However, clinical challenges in the management of HIV infected patients still remain, such as the presence of co-infections with viruses such as HBV and HPV, both involved in cancer development, as well as with tuberculosis. The symposium will focus on such pathogens, discussing the challenges in terms of clinical history, diagnosis and treatment.

    Chairs: R. Bruno, G. Taliani

    18.20 - 18.30 Critical epidemiological and virological insights on HBV coinfection
    V. Svicher
    18.30 - 18.40 HBV: from new drugs to functional cure
    M. Puoti
    18.40 - 18.50 HPV-associated ano-genital lesions in HIV patients
    M. Giuliani
    18.50 - 19.00 HPV-driven oropharyngeal cancer in the HIV/AIDS patient
    P. Boscolo Rizzo
    19.00 - 19.10 Which is the best approach to screen HIV-infected individuals for latent tuberculosis infection in Italy?
    D. Goletti
    19.10 - 19.25 Discussion on Symposium issues
  • Room 2
    15.20-16.20

    Oral Communications

    Basic Science and Immunology

    Oral Communications

    Basic Science and Immunology

    Chairs: C. Agrati, C.M. Mastroianni

    15.20 - 15.30 OC 37Reduced probability of achieving optimal viro-immunological condition in subjects with vertical transmission of HIV reaching adult age with unsuppressed HIV RNA or incomplete immunological recovery
    A. Celotti, Brescia
    15.30 - 15.40 OC 38Immunological recovery in T-cell activation after DAA treatment and SVR in HIV positive subjects with chronic hepatitis C
    F. Maggiolo, Bergamo
    15.40 - 15.50 OC 39Higher frequency of CD4+PD1+ T cells and Interferon-Stimulate Genes are associated to a decrease in CD4+ Treg levels in HIV-1 infected patients
    F. Frasca, Roma
    15.50 - 16.00